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公开(公告)号:US20160222096A1
公开(公告)日:2016-08-04
申请号:US14981643
申请日:2015-12-28
Applicant: Genentech, Inc. , AIMM THERAPEUTICS B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L.W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
IPC: C07K16/12
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US09458228B2
公开(公告)日:2016-10-04
申请号:US14728826
申请日:2015-06-02
Applicant: Genentech, Inc. , AIMM Therapeutics B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
IPC: C07K16/12
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US09969795B2
公开(公告)日:2018-05-15
申请号:US14956919
申请日:2015-12-02
Applicant: AIMM THERAPEUTICS B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Hergen Spits , Adrianus Quirinus Bakker , Koen Wagner
CPC classification number: C07K16/1018 , C07K14/4703 , C07K14/4747 , C07K16/00 , C07K2317/21 , C07K2317/565 , C07K2317/92
Abstract: The invention provides means and methods for producing high-affinity antibodies against an antigen of interest, usually stable B-cell cultures.
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公开(公告)号:US09688745B2
公开(公告)日:2017-06-27
申请号:US14981643
申请日:2015-12-28
Applicant: Genentech, Inc. , AIMM THERAPEUTICS B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US09266943B2
公开(公告)日:2016-02-23
申请号:US14103715
申请日:2013-12-11
Applicant: Genentech, Inc. , AIMM THERAPEUTICS B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US10344076B2
公开(公告)日:2019-07-09
申请号:US15048339
申请日:2016-02-19
Applicant: AIMM THERAPEUTICS B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Hergen Spits , Adrianus Quirinus Bakker
Abstract: The invention provides means and methods for modulating the occurrence of somatic hypermutations in antibody producing plasmablast-like B-cells.
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公开(公告)号:US09927428B2
公开(公告)日:2018-03-27
申请号:US15246301
申请日:2016-08-24
Applicant: Genentech, Inc. , AIMM Therapeutics B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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公开(公告)号:US09399673B2
公开(公告)日:2016-07-26
申请号:US13786206
申请日:2013-03-05
Applicant: Genentech, Inc. , AIMM Therapeutics B.V.
Inventor: Tim Beaumont , Mark Jeroen Kwakkenbos , Eric J. Brown , John Hiroshi Morisaki , Wouter L. W. Hazenbos , Sanjeev Mariathasan , Kimberly Kajihara , Yi Xia
IPC: C07K16/12
CPC classification number: G01N33/5091 , C07K16/1271 , C07K16/1278 , C07K2317/21 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/567 , G01N33/6854 , G01N33/6893 , G01N2469/10 , G01N2800/26
Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
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