公开(公告)号：US20230265398A1

公开(公告)日：2023-08-24

申请号：US18191994

申请日：2023-03-29

Applicant: AJINOMOTO CO., INC.

Inventor： Kazutoshi TAKAHASHI ,  Takuto ONO ,  Nao ARAKI ,  Hiroaki KOBAYASHI

IPC: C12N9/10 ,  A23C19/08 ,  A23C19/06 ,  A23G9/36 ,  A23G3/36 ,  A23L13/40 ,  A23L13/60 ,  A23L15/00 ,  A23L17/00 ,  A23L29/00

CPC classification number: C12N9/1044 ,  C12Y203/02013 ,  A23C19/08 ,  A23C19/063 ,  A23G9/363 ,  A23G3/366 ,  A23L13/48 ,  A23L13/60 ,  A23L15/25 ,  A23L17/65 ,  A23L29/06

Abstract: A mutant transglutaminase (mutant TG) having high thermostability and/or high pH stability is provided. A mutant TG having a mutation at amino acid residue(s) such as D1, Y24, R48, S101, G102, N139, D142, L147, K152, G157, R167, N176, K181, E182, H188, D189, R208, T245, S246, G250, G275, S284, H289, G301, and K327 and/or a mutation of introducing a disulfide bond.