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1.发明申请公开(公告)号：US20220396819A1
公开(公告)日：2022-12-15
申请号：US17831877
申请日：2022-06-03
Applicant: AJINOMOTO CO., INC.
Inventor： Kenichiro Ito , Yoshihiko Matsuda , Naoko Yamada , Yoshimi Kikuchi , Atsushi Konishi , Michiya Kanzaki , Kazutoshi Takahashi , Hiroki Yamaguchi , Ayako Fujiwara , Kyohei Miyairi
IPC: C12P21/02
Abstract: Provided are a method for producing a complicated peptide molecule, such as a dimeric peptide, in a simpler manner at lower cost compared with the conventional chemical synthesis methods; and a dimeric peptide which comprises a specific short linker and has a satisfactory activity; and others.
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公开(公告)号：US20180037918A1
公开(公告)日：2018-02-08
申请号：US15790495
申请日：2017-10-23
Applicant: AJINOMOTO CO., INC.
Inventor： Yoshihiko Matsuda , Yumi Ito , Yukari Kashima , Naoko Yamada , Noriko Tsurui , Hiroshi Itaya
CPC classification number: C12P21/00 , C07K14/34 , C07K2319/02 , C12N9/12 , C12N15/09 , C12Y207/13003
Abstract: A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, as well as a method for secretory production of a heterologous protein. A coryneform bacterium is described that has been modified to have a specific mutation so as to harbor a phoS gene, and when cultured, is able to to produce a heterologous protein by secretory production.
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公开(公告)号：US10538798B2
公开(公告)日：2020-01-21
申请号：US15790495
申请日：2017-10-23
Applicant: AJINOMOTO CO., INC.
Inventor： Yoshihiko Matsuda , Yumi Ito , Yukari Kashima , Naoko Yamada , Noriko Tsurui , Hiroshi Itaya
Abstract: A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, as well as a method for secretory production of a heterologous protein. A coryneform bacterium is described that has been modified to have a specific mutation so as to harbor a phoS gene, and when cultured, is able to to produce a heterologous protein by secretory production.
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