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Patent Agency Ranking
公开(公告)号：US20150153340A1
公开(公告)日：2015-06-04
申请号：US14310851
申请日：2014-06-20
Inventor： Seong Hyang SOHN
IPC: G01N33/569
CPC classification number: G01N33/56966 , G01N2333/70596
Abstract: The present invention relates to a composition for the diagnosis of Behcet's disease, comprising an agent for measuring the expression level of macrophage mannose receptor 1 (CD206), a kit for the diagnosis of Behcet's disease, and an information providing method using the same. According to the present invention, it is possible to diagnose the pathogenesis of Behcet's disease without being affected by symptoms of Behcet's disease or prescription drugs and differentially diagnose between active Behcet's disease and inactive Behcet's disease.
Abstract translation: 本发明涉及一种用于诊断白塞病的组合物，其包含用于测量巨噬细胞甘露糖受体1（CD206）的表达水平的试剂，用于诊断白塞病的试剂盒和使用该试剂盒的信息提供方法。 根据本发明，可以诊断白塞氏病的发病机制，而不受白塞病或处方药的症状影响，并且在活动的白塞病和不活动的贝切特病之间进行差异诊断。
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公开(公告)号：US20240150407A1
公开(公告)日：2024-05-09
申请号：US18554481
申请日：2022-04-01
Inventor： Seong Hyang SOHN
CPC classification number: C07K14/001 , A23L33/18 , A61K47/56 , A61P37/06
Abstract: The present invention relates to: a peptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOS: 4 to 7 or a fragment thereof; and a pharmaceutical composition for the treatment or prevention of inflammatory diseases or autoimmune diseases, comprising same. The peptide has been confirmed to have an excellent effect of inhibiting cytokines such as IL-17 and TNF alpha, and thus can be provided as a therapeutic agent for various inflammatory diseases, including Behcet's disease.
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公开(公告)号：US20220000943A1
公开(公告)日：2022-01-06
申请号：US17281673
申请日：2019-10-01
Inventor： Seong Hyang SOHN
IPC: A61K35/744 , A61P37/06 , A23L33/00 , A23L33/135 , A23L33/125
Abstract: A pharmaceutical composition or a health functional food composition for preventing or treating Behcet's disease have Tetragenococcus halophilus, a culture thereof or a lysate thereof. In addition, a pharmaceutical composition or a health functional food composition for preventing or treating a herpes simplex virus infection have Tetragenococcus halophilus, a culture thereof or a lysate thereof. The composition may further include a prebiotic compound. The Tetragenococcus halophilus produces lactate, and the lactate can be converted into short-chain fatty acids such as butyrate in the body, can control the expression of activating molecules of dendritic cells, and can effectively prevent or treat Behcet's disease or herpes simplex virus infection.
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公开(公告)号：US20240277785A1
公开(公告)日：2024-08-22
申请号：US18015868
申请日：2021-06-25
Inventor： Seong Hyang SOHN
IPC: A61K35/747 , A61K35/00 , A61K35/741 , A61K35/744 , A61P37/06
CPC classification number: A61K35/747 , A61K35/741 , A61K35/744 , A61P37/06 , A61K2035/115
Abstract: The present invention relates to a composition for preventing or treating inflammatory bowel disease. More specifically, the present invention provides a pharmaceutical composition and a health food composition for preventing or treating inflammatory bowel disease, comprising, as active ingredients, two or more strains selected from the group consisting of Tetragenococcus halophilus, Eubacterium rectale and Lactobacillus animalis; and cultures of the strains, concentrates of the cultures, extracts of the cultures, or lysates thereof. The composition comprises two or more strains having anti-inflammatory activity as an active ingredient and regulates immune cells related to inflammatory bowel disease, thereby preventing, ameliorating or treating inflammatory bowel disease more effectively than a single strain.
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公开(公告)号：US20240043474A1
公开(公告)日：2024-02-08
申请号：US18267882
申请日：2021-12-16
Inventor： Seong Hyang SOHN
CPC classification number: C07K7/08 , A61K47/64 , A61K47/60 , A61K47/542 , A61Q19/00 , A61K8/64 , A61P17/00 , A61K2800/57 , A61K38/00
Abstract: The present invention relates to an anti-inflammatory peptide for preventing or treating atopic dermatitis, and specifically, the present invention provides: a peptide or fragment thereof consisting of an amino acid sequence selected from the group consisting of SEQ ID NO: 1 to SEQ ID NO: 17, or a conjugate thereof; and a pharmaceutical composition and a cosmetic composition for preventing or treating atopic dermatitis comprising the peptide or fragment thereof, etc. as an active ingredient. The peptide or fragment thereof, or a conjugate thereof, has excellent anti-inflammatory activity, and thus is safe from the side effects of existing therapeutic agents for atopic dermatitis, and can effectively prevent, ameliorate, or treat atopic dermatitis.
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