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公开(公告)号:US12258410B2
公开(公告)日:2025-03-25
申请号:US18627754
申请日:2024-04-05
Applicant: Alector LLC
Inventor: Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US12258398B2
公开(公告)日:2025-03-25
申请号:US17263534
申请日:2019-07-26
Applicant: Alector LLC
Inventor: Patricia Culp , Rashmi Bankoti , Helen Lam , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a Siglec-5 protein, e.g., human Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20250026827A1
公开(公告)日:2025-01-23
申请号:US18756198
申请日:2024-06-27
Applicant: Alector LLC
Inventor: Andrew Pincetic , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPβ1 polypeptide, e.g., a human SIRPβ1, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US12247073B2
公开(公告)日:2025-03-11
申请号:US17272083
申请日:2019-08-30
Applicant: Alector LLC
Inventor: Patricia Culp , Helen Lam , Wei-Hsien Ho , Leonard G. Presta , Arnon Rosenthal
IPC: C07K16/28
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a CD33 polypeptide, e.g., a mammalian CD33 or human CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US11319373B2
公开(公告)日:2022-05-03
申请号:US16421692
申请日:2019-05-24
Applicant: Alector LLC
Inventor: Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US10711062B2
公开(公告)日:2020-07-14
申请号:US16054840
申请日:2018-08-03
Applicant: ALECTOR LLC
Inventor: Patricia Culp , Helen Lam , Arnon Rosenthal , Seung-Joo Lee , Nels P. Nielson , Robert Pejchal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind one or more epitopes within a CD33 protein, e.g., human CD33 or a mammalian CD33, and have improved and/or enhanced functional characteristics, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US11976119B2
公开(公告)日:2024-05-07
申请号:US17707637
申请日:2022-03-29
Applicant: Alector LLC
Inventor: Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
CPC classification number: C07K16/283 , C07K16/246 , C07K16/2818 , C07K16/2827 , C07K16/40 , C07K16/4283 , C12N15/85 , C07K2317/21 , C07K2317/24 , C07K2317/32 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US11965023B2
公开(公告)日:2024-04-23
申请号:US17740100
申请日:2022-05-09
Applicant: Alector LLC
Inventor: Kate Monroe , Helen Lam , Patricia Culp , Arnon Rosenthal
IPC: C07K16/28 , A61K39/00 , A61P25/00 , A61P25/08 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/00
CPC classification number: C07K16/2803 , A61P25/00 , A61P25/08 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/00 , A61K2039/505 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-5 protein, e.g., human Siglec-5 or a mammalian Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20220289844A1
公开(公告)日:2022-09-15
申请号:US17707637
申请日:2022-03-29
Applicant: Alector LLC
Inventor: Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US11359014B2
公开(公告)日:2022-06-14
申请号:US16614302
申请日:2018-05-15
Applicant: Alector LLC
Inventor: Kate Monroe , Helen Lam , Patricia Culp , Arnon Rosenthal
IPC: C07K16/28 , A61P37/00 , A61P25/28 , A61P31/04 , A61P25/00 , A61P25/08 , A61P29/00 , A61P35/00 , A61K39/00
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Siglec-5 protein, e.g., human Siglec-5 or a mammalian Siglec-5, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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