公开(公告)号：US12234469B2

公开(公告)日：2025-02-25

申请号：US17337161

申请日：2021-06-02

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Sreepriya Pramod ,  Marcos Fernando de Godoy Lusso ,  Jesse Frederick ,  Andrew Adams ,  Dongmei Xu

IPC: C12N15/82

Abstract: The present disclosure provides tobacco having genetic modification(s) in a group of ERF genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.

公开(公告)号：US10405571B2

公开(公告)日：2019-09-10

申请号：US15192480

申请日：2016-06-24

Applicant: Altria Client Services LLC

Inventor： Andrew Carl Adams ,  Marcos Fernando de Godoy Lusso ,  Sreepriya Pramod ,  Dongmei Xu

IPC: A24B15/10 ,  A24D1/04 ,  A24D3/04 ,  A01H5/12 ,  C12N15/82 ,  A24B3/12 ,  A24B13/02 ,  A24B13/00

Abstract: The present disclosure provides the identification of tobacco Nic1 locus. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Also provided are compositions and methods for producing tobacco plants having novel Nic1 mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or nicotine free while maintaining tobacco leaf grade and tobacco product quality.

公开(公告)号：US11827893B2

公开(公告)日：2023-11-28

申请号：US17067289

申请日：2020-10-09

Applicant: Altria Client Services LLC

Inventor： Sreepriya Pramod ,  Andrew C. Adams ,  Marcos Fernando de Godoy Lusso ,  Gregory A. Davis ,  Jerry W. Morris ,  Dongmei Xu ,  Jesse Frederick

IPC: C12N15/82 ,  A01H6/82

CPC classification number: C12N15/8243

Abstract: The present disclosure relates to tobacco plants, tobacco seeds, compositions, and methods related to the identification and introgression of the Pale Yellow locus in tobacco. It also relates to generating novel mutations within the PY locus in tobacco.

公开(公告)号：US11317593B2

公开(公告)日：2022-05-03

申请号：US16701872

申请日：2019-12-03

Applicant: Altria Client Services LLC

Inventor： Andrew C. Adams ,  Marcos F. de Godoy Lusso ,  Sreepriya Pramod ,  Dongmei Xu

IPC: A01H6/82 ,  A01H5/12

Abstract: The present application provides tobacco inbred plants dS1746, dS1746MS, dS1564 and dS1564MS. The present application also provides parts of such plants and products made from those parts. The present application also includes progeny of the provided plants including hybrids.

公开(公告)号：US12075746B2

公开(公告)日：2024-09-03

申请号：US16246281

申请日：2019-01-11

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Sreepriya Pramod ,  Marcos Fernando de Godoy Lusso ,  Jesse Frederick ,  Andrew Carl Adams ,  Dongmei Xu

IPC: A01H1/06 ,  A01H6/82 ,  A24B3/08 ,  A24B3/12 ,  A24B13/00 ,  A24B15/10 ,  A24B15/20 ,  A24B15/24 ,  C12N15/82

CPC classification number: A01H6/823 ,  A01H1/06 ,  A24B3/08 ,  A24B3/12 ,  A24B13/00 ,  A24B15/10 ,  A24B15/20 ,  A24B15/243 ,  C12N15/8218 ,  C12N15/8227

Abstract: The present disclosure provides tobacco Nic1b locus and associated genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.

公开(公告)号：US11950563B2

公开(公告)日：2024-04-09

申请号：US16246308

申请日：2019-01-11

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Sreepriya Pramod ,  Marcos Fernando de Godoy Lusso ,  Jesse Frederick ,  Andrew Carl Adams ,  Dongmei Xu

IPC: C12N15/82 ,  A01H1/06 ,  A01H6/82 ,  A24B3/08 ,  A24B3/12 ,  A24B13/00 ,  A24B15/10 ,  A24B15/20 ,  A24B15/24

CPC classification number: A01H6/823 ,  A01H1/06 ,  A24B3/08 ,  A24B3/12 ,  A24B13/00 ,  A24B15/10 ,  A24B15/20 ,  A24B15/243 ,  C12N15/8218 ,  C12N15/8227

Abstract: The present disclosure provides tobacco Nic1b locus and associated genes (e.g., a group of ERF genes). Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.

公开(公告)号：US12274230B2

公开(公告)日：2025-04-15

申请号：US18321594

申请日：2023-05-22

Applicant: Altria Client Services LLC

Inventor： Andrew C. Adams ,  Marcos F. de Godoy Lusso ,  Sreepriya Pramod ,  Dongmei Xu

IPC: A01H6/82 ,  A01H5/12 ,  A24B15/10

Abstract: The present application provides tobacco inbred plants dS1746, dS1746MS, dS1564 and dS1564MS. The present application also provides parts of such plants and products made from those parts. The present application also includes progeny of the provided plants including hybrids.

公开(公告)号：US20230329168A1

公开(公告)日：2023-10-19

申请号：US18170372

申请日：2023-02-16

Applicant: Altria Client Services LLC

Inventor： Andrew Carl Adams ,  Marcos Fernando de Godoy Lusso ,  Sreepriya Pramod ,  Dongmei Xu

IPC: A24B15/10 ,  A01H5/12 ,  A24B13/00 ,  C12N15/82 ,  A01H6/82 ,  A24B3/12 ,  A24B13/02 ,  A24D1/04

CPC classification number: A24B15/10 ,  A01H5/12 ,  A24B13/00 ,  C12N15/8243 ,  A01H6/823 ,  A24B3/12 ,  A24B13/02 ,  A24D1/045

Abstract: The present disclosure provides the identification of tobacco Nic1 locus. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Also provided are compositions and methods for producing tobacco plants having novel Nic1 mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or nicotine free while maintaining tobacco leaf grade and tobacco product quality.

公开(公告)号：US11690347B2

公开(公告)日：2023-07-04

申请号：US17704650

申请日：2022-03-25

Applicant: Altria Client Services LLC

Inventor： Andrew C. Adams ,  Marcos F. de Godoy Lusso ,  Sreepriya Pramod ,  Dongmei Xu

IPC: A01H5/12 ,  A01H6/82

CPC classification number: A01H6/823 ,  A01H5/12

Abstract: The present application provides tobacco inbred plants dS1746, dS1746MS, dS1564 and dS1564MS. The present application also provides parts of such plants and products made from those parts. The present application also includes progeny of the provided plants including hybrids.

公开(公告)号：US20190309317A1

公开(公告)日：2019-10-10

申请号：US16471960

申请日：2017-12-20

Applicant: Altria Client Services LLC

Inventor： Andrew Carl Adams ,  Marcos Fernando de Godoy Lusso ,  Sreepriya Pramod ,  Dongmei Xu

IPC: C12N15/82 ,  A24B3/12 ,  A24B15/20 ,  A24B13/00

Abstract: The present disclosure provides the identification of tobacco Nic1 locus. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Also provided are compositions and methods for producing tobacco plants having novel Nic1 mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or nicotine free while maintaining tobacco leaf grade and tobacco product quality.