公开(公告)号：US20240140899A1

公开(公告)日：2024-05-02

申请号：US18499697

申请日：2023-11-01

Applicant: AMALGAMATED RESEARCH LLC

Inventor： Lily Crane ,  Peter V. Ferrero

IPC: C07C51/47 ,  B01D15/18 ,  B01D15/36 ,  B01J39/05 ,  B01J39/18 ,  B01J47/10

CPC classification number: C07C51/47 ,  B01D15/1828 ,  B01D15/1842 ,  B01D15/362 ,  B01J39/05 ,  B01J39/18 ,  B01J47/10

Abstract: Systems and methods for enriching an organic acid from a fermentation broth containing residual color, salts, and carbohydrates using simulated moving bed (“SMB”) chromatography to produce a high purity organic acid extract is disclosed. One embodiment of the method purifies citric acid from a fermentation broth into two product streams: a first product stream rich in salt, color, and carbohydrate impurities, and a second product stream comprising an extract enriched in organic acid.