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    3 4-dihydroacridin-2-(1h)-one derivatives
    2.
    发明授权
    3 4-dihydroacridin-2-(1h)-one derivatives 失效
    3 4-二氢吡啶-2-（1H） - 酮衍生物

    公开(公告)号：US3649632A

    公开(公告)日：1972-03-14

    申请号：US3649632D

    申请日：1970-01-27

    Applicant: AMERICAN HOME PROD

    Inventor： DIEBOLD JAMES L ,  WOLF MILTON

    IPC: C07D219/06 ,  C07D37/18

    CPC classification number: C07D219/06

    Abstract: THE DISCLOSURE IS DIRECTED TO NOVEL 3,4-DIHYDROACRIDIN2(1H)-ONE DERIVATIVES OBTAINED BY THE REACTION OF OAMINOCARBONYL DERIVATIVES WITH CYCLOHEXANE-1,4-DIONE IN THE PRESENCE OF A STRONG ACID. THE COMPOUNDS ARE USEFUL AS CENTRAL NERVOUS SYSTEM DEPRESSANTS IN THAT THEY PRODUCE A CALMING EFFECT IN THE HOST.

    2,10-disubstituted-1,2,3,4-tetrahydrobenzo(bhq (1,6)naphthyridines useful as cns depressants
    4.
    发明授权
    2,10-disubstituted-1,2,3,4-tetrahydrobenzo(bhq (1,6)naphthyridines useful as cns depressants 失效
    2,10-取代的-1,2,3,4-四氢苯并噻唑（BHQ（1,6）萘啶酮可用作CNS DEPRESSANTS

    公开(公告)号：US3674790A

    公开(公告)日：1972-07-04

    申请号：US3674790D

    申请日：1970-05-01

    Applicant: AMERICAN HOME PROD

    Inventor： WOLF MILTON ,  DIEBOLD JAMES L

    IPC: C07D471/04 ,  C07D39/00

    CPC classification number: C07D471/04

    Abstract: This invention concerns 1,2,3,4tetrahydrobenzo(b)(1,6)naphthyridines, 1,2,3,4,4a,5,10,10aoctahydrobenzo(b)(1,6)naphthyridines and the pharmacologically acceptable acid addition salts thereof which are pharmacologically active as central nervous system depressants which are useful in producing a calming effect in warm-blooded animals. Further, this invention concerns a process for the preparation of 10-amino-1,2,3,4tetrahydrobenzo(b)(1,6)naphthyridines.

    1,2,3,4-tetrahydrobenzol(b)(1,6)naphthyridine derivatives
    8.
    发明授权
    1,2,3,4-tetrahydrobenzol(b)(1,6)naphthyridine derivatives 失效
    1,2,3,4-四氢苯并噻唑（B）（1,6）萘啶衍生物

    公开(公告)号：US3580915A

    公开(公告)日：1971-05-25

    申请号：US3580915D

    申请日：1968-09-16

    Applicant: AMERICAN HOME PROD

    Inventor： WOLF MILTON ,  DIEBOLD JAMES L

    IPC: C07D471/04 ,  C07D39/00

    CPC classification number: C07D471/04

    Abstract: THIS INVENTION CONCERNS 1,2,3,4-TETRAHYDROBENZO(B) (1,6)NAPHTHYRIDINE, 1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO (B)(1,6)NAPHTHYRIDINES AND THE PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF WHICH ARE PHARMACOLOGICALLY ACTIVE AS CENTRAL NERVOUS SYSTEM DEPRESSANTS WHICH ARE USEFUL IN PRODUCING A CALMING EFFECT IN WARMBLOODED ANIMALS. FURTHER, THIS INVENTION CONCERNS A PROCESS FOR THE PREPARATION OF 10-AMINO-1,2,3,4-TETRAHYDROBENZO(B)(1,6)NAPHTHYRIDINES.

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