公开(公告)号：US20210163531A1

公开(公告)日：2021-06-03

申请号：US17046662

申请日：2019-03-28

Applicant: AMGEN INC.

Inventor： William Callahan ,  Lorenzo Desantiago ,  Clea Talley ,  Yael Wexler-Cohen ,  Jeffrey Abel ,  Rahul Kaushik ,  Nitya Mariam Jacob ,  Carson Tran ,  Nicole Ball ,  Monica Goss

IPC: C07K1/36 ,  C07K1/34 ,  C07K1/18 ,  C07K1/16 ,  C07K16/28 ,  C07K16/30 ,  C07K14/535 ,  C07K14/505 ,  C07K14/71 ,  C07K14/715 ,  C07K16/40 ,  C07K16/32 ,  C07K16/22 ,  C07K16/18

Abstract: The invention relates to methods for preparing stable buffered and buffer-free protein compositions. The invention also relates to methods of purifying proteins from one or more impurities.

公开(公告)号：US20220362104A1

公开(公告)日：2022-11-17

申请号：US17770355

申请日：2020-10-23

Applicant: AMGEN INC. ,  AMGEN RESEARCH MUNICH GMBH

Inventor： Cornelius Pompe ,  Nicholas J. Clark ,  Wei Qi ,  Arnold J. McAuley ,  MIchael Schneider ,  Chia-Jung Wu ,  Twinkle R. Christian ,  Heather N. Franey ,  Bharadwaj Jagannathan ,  Jeffrey Abel ,  Franz Dietzel

IPC: A61J1/14 ,  A61M5/14 ,  G01N33/15

Abstract: An approach for determining material compatibility for components of a drug delivery system is provided that includes using surface zeta-potential analytical method to evaluate surface interactions between a desired molecule and at least one material present within a given IV-bag system.