公开(公告)号：US11491223B2

公开(公告)日：2022-11-08

申请号：US16144120

申请日：2018-09-27

Applicant: AMGEN INC.

Inventor： Monica Goss ,  Nicole Ball

IPC: A61K38/17 ,  C07K14/715 ,  A61K39/395 ,  A61K47/02 ,  A61K47/26 ,  A61K9/08 ,  A61K47/18 ,  A61K9/00 ,  C07K19/00 ,  A61P19/02 ,  A61P17/06 ,  A61P29/00

Abstract: The invention relates to the formulation of pharmaceutical compositions of etanercept. The invention also relates to methods of removing buffer and of formulating pharmaceutical compositions of etanercept.

公开(公告)号：US12214013B2

公开(公告)日：2025-02-04

申请号：US17933055

申请日：2022-09-16

Applicant: AMGEN INC.

Inventor： Monica Goss ,  Nicole Ball

IPC: A61P19/02 ,  A61K9/00 ,  A61K9/08 ,  A61K38/17 ,  A61K39/395 ,  A61K47/02 ,  A61K47/18 ,  A61K47/26 ,  A61K47/68 ,  A61P17/06 ,  A61P29/00 ,  C07K14/715 ,  C07K19/00

Abstract: The invention relates to the formulation of pharmaceutical compositions of etanercept. The invention also relates to methods of removing buffer and of formulating pharmaceutical compositions of etanercept.

公开(公告)号：US20210163531A1

公开(公告)日：2021-06-03

申请号：US17046662

申请日：2019-03-28

Applicant: AMGEN INC.

Inventor： William Callahan ,  Lorenzo Desantiago ,  Clea Talley ,  Yael Wexler-Cohen ,  Jeffrey Abel ,  Rahul Kaushik ,  Nitya Mariam Jacob ,  Carson Tran ,  Nicole Ball ,  Monica Goss

IPC: C07K1/36 ,  C07K1/34 ,  C07K1/18 ,  C07K1/16 ,  C07K16/28 ,  C07K16/30 ,  C07K14/535 ,  C07K14/505 ,  C07K14/71 ,  C07K14/715 ,  C07K16/40 ,  C07K16/32 ,  C07K16/22 ,  C07K16/18

Abstract: The invention relates to methods for preparing stable buffered and buffer-free protein compositions. The invention also relates to methods of purifying proteins from one or more impurities.

公开(公告)号：US20190022217A1

公开(公告)日：2019-01-24

申请号：US16144120

申请日：2018-09-27

Applicant: AMGEN INC.

Inventor： Monica Goss ,  Nicole Ball

IPC: A61K39/395 ,  A61K38/17 ,  A61K47/18 ,  A61K47/26 ,  A61K47/02 ,  A61K9/08

Abstract: The invention relates to the formulation of pharmaceutical compositions of etanercept. The invention also relates to methods of removing buffer and of formulating pharmaceutical compositions of etanercept.

公开(公告)号：US20180256718A1

公开(公告)日：2018-09-13

申请号：US15958261

申请日：2018-04-20

Applicant: AMGEN INC.

Inventor： Monica Goss ,  Nicole Ball

IPC: A61K39/395 ,  A61K38/17 ,  A61K47/18 ,  A61K47/26 ,  A61K47/02 ,  A61K9/08

CPC classification number: A61K39/39591 ,  A61K9/08 ,  A61K38/1793 ,  A61K47/02 ,  A61K47/183 ,  A61K47/26 ,  C07K14/7151 ,  C07K19/00 ,  C07K2319/30

Abstract: The invention relates to the formulation of pharmaceutical compositions of etanercept. The invention also relates to methods of removing buffer and of formulating pharmaceutical compositions of etanercept.

公开(公告)号：US20230080571A1

公开(公告)日：2023-03-16

申请号：US17933055

申请日：2022-09-16

Applicant: AMGEN INC.

Inventor： Monica Goss ,  Nicole Ball

IPC: A61K39/395 ,  A61K47/02 ,  A61K38/17 ,  A61K47/26 ,  A61K9/08 ,  A61K47/18 ,  C07K14/715 ,  A61K9/00

Abstract: The invention relates to the formulation of pharmaceutical compositions of etanercept. The invention also relates to methods of removing buffer and of formulating pharmaceutical compositions of etanercept.

公开(公告)号：US20220087901A1

公开(公告)日：2022-03-24

申请号：US17425412

申请日：2020-02-12

Applicant: AMGEN INC.

Inventor： Nicholas J. Clark ,  Chia-Jung Wu ,  Mingda Eu ,  Artemio A. Alanis ,  Jennifer Lyn Sawicky ,  Monica Goss ,  Jennifer Stevenson ,  Heather N. Franey ,  Deirdre Piedmonte ,  Stephen Robert Brych

IPC: A61J1/20 ,  A61M39/00

Abstract: An approach for preparing a drug delivery device includes providing a prefilled delivery container and transferring a drug product contained in a drug container to the prefilled delivery container. The prefilled delivery container includes a container body containing a predetermined quantity of saline solution and a predetermined quantity of IV stabilizing solution (“IVSS”). The drug product is transferred to the prefilled delivery container via a delivery container adapter.

公开(公告)号：US10307483B2

公开(公告)日：2019-06-04

申请号：US15958261

申请日：2018-04-20

Applicant: AMGEN INC.

Inventor： Monica Goss ,  Nicole Ball

IPC: A61K38/17 ,  A61K39/395 ,  A61K47/02 ,  A61K47/26 ,  A61K9/08 ,  A61K47/18 ,  C07K14/715 ,  C07K19/00

Abstract: The invention relates to the formulation of pharmaceutical compositions of etanercept. The invention also relates to methods of removing buffer and of formulating pharmaceutical compositions of etanercept.