公开(公告)号：US20170304175A1

公开(公告)日：2017-10-26

申请号：US15521570

申请日：2015-11-27

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun Kyung LEE ,  Myeong Jin GOH ,  Hyun Jung CHOI ,  Eun Gyung CHO ,  Tae Ryong LEE

IPC: A61K8/49 ,  A61Q5/00 ,  A61Q19/08

CPC classification number: A61K8/498 ,  A61K8/49 ,  A61K31/352 ,  A61K31/353 ,  A61K2800/78 ,  A61K2800/91 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/08

Abstract: The present disclosure discloses a novel use of genistein, epigallocatechin gallate (EGCG), derivatives thereof, isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof and solvates thereof. A composition containing genistein, epigallocatechin gallate, derivatives thereof isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof or solvates thereof reduces the expression of factors related to increase of melanin producing ability, reduces the expression of senescence marker proteins and regulates the expression of enzymes involved in melanin production, and thus may have an effect of rejuvenating cells including melanocytes.

公开(公告)号：US20200345694A1

公开(公告)日：2020-11-05

申请号：US16759211

申请日：2018-07-24

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Jung CHOI ,  Hyoung June KIM ,  Ji Yong JUNG ,  Tae Ryong LEE

IPC: A61K31/4035 ,  A61K31/4436 ,  A61K36/06 ,  A61K8/49 ,  A61K8/9728 ,  A23L33/10 ,  A61Q19/08

Abstract: The present disclosure relates to an antiaging composition containing cytochalasin D or SAG, and a method for screening an antiaging substance, and provides a new antiaging substance and a new method for discovering a new antiaging substance. Thus, it is possible to greatly contribute to the development of beauty industries and to meeting demands related with beauty and antiaging, if the present disclosure is effectively used.

公开(公告)号：US20170209358A1

公开(公告)日：2017-07-27

申请号：US15329316

申请日：2015-07-24

Applicant: Amorepacific Corporation

Inventor： Eun Kyung LEE ,  Ji Yeon HAN ,  Eun Gyung CHO ,  Tae Ryong LEE ,  Hyun Jung CHOI

IPC: A61K8/64

CPC classification number: A61K8/64 ,  A61K38/19 ,  A61Q19/02

Abstract: The present invention relates to a composition containing a chemokine, particularly, an interferon-inducible T-cell alpha chemoattractant (ITACT) which can decrease the gene expression of a factor related to melanin pigment production in melanocytes, thereby exhibiting a skin whitening effect.

公开(公告)号：US20130303605A1

公开(公告)日：2013-11-14

申请号：US13939807

申请日：2013-07-11

Applicant: Amorepacific Corporation

Inventor： Hui Kyoung CHANG ,  Dae Gun KIM ,  Myeong Hoon YEOM ,  Hyun Jung CHOI ,  Kyung Mi JOO ,  Jae Sung HWANG ,  Soo Mi AHN

IPC: A61K8/49 ,  A61Q19/02

CPC classification number: A61K8/4973 ,  A61K31/343 ,  A61Q19/02

Abstract: Disclosed herein are an external composition for skin, which contains, as an active ingredient, manassantin B extracted from Saururus chinensis Baill, and the use thereof for skin whitening. More particularly, disclosed are an external composition for skin, which contains, as an active ingredient, manassantin B, which inhibits the transfer of melanosomes, thus providing a skin-whitening effect without influencing the melanin synthesis function of the melanocytes, as well as the use thereof for skin whitening.

Abstract translation: 本发明公开了一种皮肤外用组合物，其含有作为活性成分的从中华黄ensis提取的马桑丁B及其用于皮肤美白的用途。 更具体地，公开了一种皮肤外用组合物，其含有抑制黑素体转移的马桑丁汀B作为活性成分，从而提供皮肤美白效果而不影响黑素细胞的黑色素合成功能，以及 其用于皮肤美白。