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公开(公告)号:US20230008130A1
公开(公告)日:2023-01-12
申请号:US17869351
申请日:2022-07-20
发明人: Stephen J. Baker , Virginia Sanders , Tsutomu Akama , Carolyn Bellinger-Kawahara , Yvonne Freund , Kirk R. Maples , Jacob J. Plattner , Yong-Kang Zhang , Huchen Zhou , Vincent S. Hernandez
摘要: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.
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公开(公告)号:US20210070779A1
公开(公告)日:2021-03-11
申请号:US17066033
申请日:2020-10-08
发明人: Tsutomu Akama , Jacob J. Plattner
摘要: Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions are disclosed.
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公开(公告)号:US20200207789A1
公开(公告)日:2020-07-02
申请号:US16813090
申请日:2020-03-09
发明人: Tsutomu AKAMA , Jacob J. Plattner
摘要: Compounds, pharmaceutical formulations, and methods of treating anti-inflammatory conditions are disclosed.
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公开(公告)号:US20200179418A1
公开(公告)日:2020-06-11
申请号:US16789777
申请日:2020-02-13
发明人: Stephen J. Baker , Virginia Sanders , Tsutomo Akama , Carolyn Bellinger-Kawahara , Yvonne Freund , Kirk R. Maples , Jacob J. Plattner , Yong-Kang Zhang , Huchen Zhou , Vincent S. Hernandez
摘要: Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.
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公开(公告)号:US10562921B2
公开(公告)日:2020-02-18
申请号:US15590159
申请日:2017-05-09
发明人: Tsutomu Akama , David Scott Carter , Jason S. Halladay , Robert T. Jacobs , Yang Liu , Jacob J. Plattner , Yong-Kang Zhang , Michael John Witty
IPC分类号: A61K31/166 , C07F5/02 , A61K31/443 , A61K31/4525 , A61K31/69 , A61K31/4178 , A61K31/431 , A61K31/47 , A61K31/5377
摘要: The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.
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公开(公告)号:US10308668B2
公开(公告)日:2019-06-04
申请号:US15792251
申请日:2017-10-24
发明人: Michael Richard Kevin Alley , Vincent Hernandez , Jacob J. Plattner , Xianfeng Li , David Barros-Aguirre , Ilaria Giordano
摘要: Compounds of Formula II, wherein X is selected from chloro, fluoro, bromo and iodo, R1 and R2 are each independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, or —CH(CH3)2; compositions containing them, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.
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公开(公告)号:US10301329B2
公开(公告)日:2019-05-28
申请号:US15227112
申请日:2016-08-03
发明人: Daitao Chen , Matthew Orr , Jessica Sligar , Robert Jacobs , Jacob J. Plattner
摘要: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
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公开(公告)号:US20180065994A1
公开(公告)日:2018-03-08
申请号:US15801127
申请日:2017-11-01
发明人: Tsutomu AKAMA , Eric Easom , Yvonne Freund , Jacob J. Plattner , Jessica Sligar , Daitao Chen , Jennifer Freeman , Joe Perales
摘要: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
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公开(公告)号:US20170355719A1
公开(公告)日:2017-12-14
申请号:US15685846
申请日:2017-08-24
发明人: Vincent S. Hernandez , Charles Ding , Jacob J. Plattner , Michael Richard Kevin Alley , Fernando Rock , Suoming Zhang , Eric Easom , Xianfeng Li , Ding Zhou
IPC分类号: C07F5/02
CPC分类号: C07F5/025
摘要: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
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公开(公告)号:US09751898B2
公开(公告)日:2017-09-05
申请号:US14221637
申请日:2014-03-21
发明人: Vincent S. Hernandez , Charles Ding , Jacob J. Plattner , Michael Richard Kevin Alley , Fernando Rock , Suoming Zhang , Eric Easom , Xianfeng Li , Ding Zhou
IPC分类号: C07F5/02
CPC分类号: C07F5/025
摘要: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
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