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公开(公告)号:US20180016285A1
公开(公告)日:2018-01-18
申请号:US15718422
申请日:2017-09-28
发明人: Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
摘要: This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
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公开(公告)号:US20170355719A1
公开(公告)日:2017-12-14
申请号:US15685846
申请日:2017-08-24
发明人: Vincent S. Hernandez , Charles Ding , Jacob J. Plattner , Michael Richard Kevin Alley , Fernando Rock , Suoming Zhang , Eric Easom , Xianfeng Li , Ding Zhou
IPC分类号: C07F5/02
CPC分类号: C07F5/025
摘要: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
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公开(公告)号:US09751898B2
公开(公告)日:2017-09-05
申请号:US14221637
申请日:2014-03-21
发明人: Vincent S. Hernandez , Charles Ding , Jacob J. Plattner , Michael Richard Kevin Alley , Fernando Rock , Suoming Zhang , Eric Easom , Xianfeng Li , Ding Zhou
IPC分类号: C07F5/02
CPC分类号: C07F5/025
摘要: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
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公开(公告)号:US20150119364A1
公开(公告)日:2015-04-30
申请号:US14537771
申请日:2014-11-10
发明人: Stephen J. BAKER , Tsutomu Akama , Michael Richard Kevin Alley , Stephen J. Benkovic , Michael DiPierro , Vincent S. Hernandez , Karin M. Hold , Isaac Kennedy , Igor Likhotvorik , Weimin Mao , Kirk Maples , Jacob J. Plattner , Fernando Rock , Virginia Sanders , Aaron M. Stemphoski , George Petros Yiannikouros , Siead Zegar , Yong-Kang Zhang , Huchen Zhou
IPC分类号: C07F5/04
CPC分类号: C07F5/025 , A61K9/0012 , A61K9/08 , A61K31/69 , A61K31/70 , A61K31/7076 , A61K47/10 , C07F5/04 , C07H19/06 , C07H19/16 , C07H21/00 , C07H23/00 , Y02A50/473
摘要: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
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公开(公告)号:US11008345B2
公开(公告)日:2021-05-18
申请号:US16526248
申请日:2019-07-30
发明人: Vincent S. Hernandez , Charles Ding , Jacob J. Plattner , Michael Richard Kevin Alley , Fernando Rock , Suoming Zhang , Eric Easom , Xianfeng Li , Ding Zhou
IPC分类号: C07F5/02
摘要: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
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公开(公告)号:US10533021B2
公开(公告)日:2020-01-14
申请号:US15718422
申请日:2017-09-28
发明人: Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
摘要: This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
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公开(公告)号:US20140221631A1
公开(公告)日:2014-08-07
申请号:US14201459
申请日:2014-03-07
发明人: Stephen J. BAKER , Tsutomu Akama , Michael Richard Kevin Alley , Stephen J. Benkovic , Michael Dipierro , Vincent S. Hernandez , Karin M. Hold , Isaac Kennedy , Igor Likhotvorik , Weimin Mao , Kirk Maples , Jacob J. Plattner , Fernando Rock , Virginia Sanders , Aaron M. Stemphoski , George Petros Yiannikouros , Siead Zagar , Yong-Kang Zhang , Huchen Zhou
CPC分类号: C07F5/025 , A61K9/0012 , A61K9/08 , A61K31/69 , A61K31/70 , A61K31/7076 , A61K47/10 , C07F5/04 , C07H19/06 , C07H19/16 , C07H21/00 , C07H23/00 , Y02A50/473
摘要: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
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公开(公告)号:US09796735B2
公开(公告)日:2017-10-24
申请号:US14536483
申请日:2014-11-07
发明人: Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
CPC分类号: C07F5/025 , A61K31/69 , Y02A50/387
摘要: The compounds are of the class of 3,7 substituted benzoxaboroles, useful for killing and/or inhibiting the growth of microorganisms.
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公开(公告)号:US09353133B2
公开(公告)日:2016-05-31
申请号:US14201459
申请日:2014-03-07
发明人: Stephen J. Baker , Tsutomu Akama , Michael Richard Kevin Alley , Stephen J. Benkovic , Michael DiPierro , Vincent S. Hernandez , Karin M. Hold , Isaac Kennedy , Igor Likhotvorik , Weimin Mao , Kirk Maples , Jacob J. Plattner , Fernando Rock , Virginia Sanders , Aaron M. Stemphoski , George Petros Yiannikouros , Siead Zegar , Yong-Kang Zhang , Huchen Zhou
IPC分类号: C07F5/04 , C07F5/02 , C07H19/06 , C07H19/16 , C07H21/00 , C07H23/00 , A61K31/69 , A61K31/70 , A61K31/7076
CPC分类号: C07F5/025 , A61K9/0012 , A61K9/08 , A61K31/69 , A61K31/70 , A61K31/7076 , A61K47/10 , C07F5/04 , C07H19/06 , C07H19/16 , C07H21/00 , C07H23/00 , Y02A50/473
摘要: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
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公开(公告)号:US20140315860A1
公开(公告)日:2014-10-23
申请号:US14221637
申请日:2014-03-21
发明人: Vincent S. HERNANDEZ , Charles Ding , Jacob J. Plattner , Michael Richard Kevin Alley , Fernando Rock , Suoming Zhang , Eric Easom , Xianfeng Li , Ding Zhou
IPC分类号: C07F5/02
CPC分类号: C07F5/025
摘要: This invention relates to, among other items, benzoxaborole compounds and their use for treating bacterial infections.
摘要翻译: 本发明涉及苯并恶唑化合物及其用于治疗细菌感染的用途。
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