-
1.发明授权公开(公告)号：US09821325B2
公开(公告)日：2017-11-21
申请号：US14780766
申请日：2014-04-28
Inventor： Uwe Weierstall , John Spence , R. Bruce Doak
CPC classification number: B05B1/10 , B05B1/02 , B05B7/064 , B05B7/066 , B05B7/08 , B05B7/24 , C30B7/00 , C30B7/02 , C30B29/58
Abstract: An injector apparatus and methods for use, where the injector apparatus comprises: (a) hydraulic stage having first and second ends and including a housing defining a cavity, a primary plunger disposed in the cavity and a secondary plunger, (b) a pressurization system coupled to the hydraulic stage's first end, where the primary plunger is in fluid communication with the pressurization system and is in mechanical communication with the secondary plunger, (c) a reservoir bore defined in the hydraulic stage housing and configured to receive the primary plunger's second end, where the secondary plunger is disposed within the reservoir bore and (d) a nozzle assembly including a housing, a gas tube and a nozzle capillary, where the nozzle capillary is partially disposed in and is substantially coaxial with the gas tube, where the nozzle capillary's first end is in fluid communication with the reservoir bore's second end.
-
公开(公告)号：US10557807B2
公开(公告)日：2020-02-11
申请号：US16328262
申请日：2018-05-22
Inventor： Alexandra Ros , Gerrit Brehm , Garrett Nelson , John Spence , Uwe Weierstall , Austin Echelmeier
IPC: G01N23/2005 , B01F13/00 , B33Y80/00 , G01N23/20025 , B01L3/00
Abstract: A 3D printed hybrid nozzle device combining a microfluidic mixer with a liquid jet injector that addresses the bottleneck of investigating substrate-initiated biological reaction paths employing serial crystallography with XFELs. The hybrid nozzle provides for injecting aqueous protein crystal jets after fast mixing (
-
Search Results
2
records
(took 0.031 seconds)
