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公开(公告)号：US20220362375A1
公开(公告)日：2022-11-17
申请号：US17743058
申请日：2022-05-12
Inventor： Yung Chang , Sidney Hecht , Joseph Leal , Viswanath Arutla , Xiaowei Liu , Sriram Sokalingam
IPC: A61K39/385 , C07D401/14 , G16B15/00 , G16B20/00 , A61K47/64 , G01N33/94 , A61K39/00 , G16B15/30 , G16B20/30
Abstract: Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
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公开(公告)号：US11254941B2
公开(公告)日：2022-02-22
申请号：US16642792
申请日：2018-08-30
Inventor： Hao Yan , Yung Chang , Xiaowei Liu , Fei Zhang , Xiaodong Qi
IPC: C12N15/117 , B82Y5/00
Abstract: Certain embodiments provide RNA nanostructure (e.g., comprising one single-stranded RNA (ssRNA) molecule, wherein the RNA nanostructure comprises at least one paranemic cohesion crossover), as well as compositions and methods of use thereof. In certain embodiments, such RNA nanostructures are immuno-modulatory (e.g., immuno-stimulatory).
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公开(公告)号：US20160375131A1
公开(公告)日：2016-12-29
申请号：US15189930
申请日：2016-06-22
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Yung Chang , Sidney Hecht , Joseph Leal , Viswanath Arutla , Xiaowei Liu , Sriram Sokalingam , Paul Pentel
IPC: A61K39/385 , G01N33/94 , G06F19/16 , G06F19/18 , C07D401/14 , A61K47/48
CPC classification number: A61K39/385 , A61K39/0013 , A61K47/646 , A61K2039/6012 , C07D401/14 , G01N33/946 , G06F19/16 , G06F19/18
Abstract: Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
Abstract translation: 本文提供了尼古丁半抗原合理设计的方法。 更具体地，本文提供了用于设计，选择和合成尼古丁半抗原和尼古丁半抗原共轭物的方法。 本文还提供了新型尼古丁半抗原以及使用尼古丁半抗原来治疗尼古丁成瘾的方法。
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Patent Agency Ranking
公开(公告)号：US11357848B2
公开(公告)日：2022-06-14
申请号：US15863118
申请日：2018-01-05
Inventor： Yung Chang , Sidney Hecht , Joseph Leal , Viswanath Arutla , Xiaowei Liu , Sriram Sokalingam
IPC: A61K39/385 , C07D401/14 , G16B15/00 , G16B20/00 , A61K47/64 , G01N33/94 , A61K39/00 , G16B15/30 , G16B20/30
Abstract: Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
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公开(公告)号：US20180125969A1
公开(公告)日：2018-05-10
申请号：US15863118
申请日：2018-01-05
Inventor： Yung Chang , Sidney Hecht , Joseph Leal , Viswanath Arutla , Xiaowei Liu , Sriram Sokalingam
IPC: A61K39/385 , C07D401/14 , G06F19/16 , G06F19/18 , A61K47/64
CPC classification number: A61K39/385 , A61K39/0013 , A61K47/646 , A61K2039/6012 , C07D401/14 , G01N33/946 , G16B15/00 , G16B20/00
Abstract: Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
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公开(公告)号：US11712467B2
公开(公告)日：2023-08-01
申请号：US17743058
申请日：2022-05-12
Inventor： Yung Chang , Sidney Hecht , Joseph Leal , Viswanath Arutla , Xiaowei Liu , Sriram Sokalingam
IPC: A61K39/385 , G16B15/00 , G16B20/30 , G16B20/00 , C07D401/14 , A61K47/64 , G01N33/94 , A61K39/00 , G16B15/30
CPC classification number: A61K39/385 , A61K39/0013 , A61K47/646 , C07D401/14 , G01N33/946 , G16B15/00 , G16B15/30 , G16B20/00 , G16B20/30 , A61K2039/6012
Abstract: Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
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公开(公告)号：US09884114B2
公开(公告)日：2018-02-06
申请号：US15189930
申请日：2016-06-22
Inventor： Yung Chang , Sidney Hecht , Joseph Leal , Viswanath Arutla , Xiaowei Liu , Sriram Sokalingam
IPC: A61K39/385 , C07D401/14 , G06F19/16 , G06F19/18 , A61K47/64
CPC classification number: A61K39/385 , A61K39/0013 , A61K47/646 , A61K2039/6012 , C07D401/14 , G01N33/946 , G06F19/16 , G06F19/18
Abstract: Provided herein are methods for rational design of nicotine haptens. More particularly, provided herein are methods for designing, selecting, and synthesizing nicotine haptens and nicotine hapten conjugates. Also provided herein are novel nicotine haptens and methods for using nicotine haptens to treat nicotine addiction.
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公开(公告)号：US20230038866A1
公开(公告)日：2023-02-09
申请号：US17814407
申请日：2022-07-22
Inventor： Xiaodong Qi , Hao Yan , Peter Nakaji , Joseph Georges , Xiaowei Liu
IPC: G01N33/53 , C12N15/115
Abstract: Disclosed are methods of detecting and treating suspected B-cell lymphoma.
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