公开(公告)号：US20170000796A1

公开(公告)日：2017-01-05

申请号：US15203424

申请日：2016-07-06

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Gordon SAXTY ,  Christopher Charles Frederick HAMLETT ,  Valerio BERDINI ,  Christopher William MURRAY ,  Patrick René ANGIBAUD ,  Olivier Alexis Georges QUEROLLE ,  Virginie Sophie PONCELET

IPC: A61K31/519

CPC classification number: A61K31/519 ,  A61K45/06 ,  C07D475/00

Abstract: The invention relates to new pteridine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract translation: 本发明涉及新的蝶啶衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法以及所述化合物在治疗疾病中的用途。 癌症。

公开(公告)号：US20150353537A1

公开(公告)日：2015-12-10

申请号：US14436319

申请日：2013-10-18

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Gianni CHESSARI ,  Christopher Norbert JOHNSON ,  Lee William PAGE ,  Ildiko Maria BUCK ,  James Edward Harvey DAY ,  Steven HOWARD ,  Gordon SAXTY ,  Christopher William MURRAY

IPC: C07D471/04 ,  C07D519/00

CPC classification number: C07D403/14 ,  C07D471/04 ,  C07D519/00

Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

公开(公告)号：US20160220564A1

公开(公告)日：2016-08-04

申请号：US15014156

申请日：2016-02-03

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Steven John WOODHEAD ,  Christopher William MURRAY ,  Valerio BERDINI ,  Gordon SAXTY ,  Gilbert Ebai BESONG ,  Lieven MEERPOEL ,  Olivier Alexis Georges QUEROLLE ,  Virginie Sophie PONCELET

IPC: A61K31/498 ,  A61K31/506 ,  A61K31/5377

CPC classification number: A61K31/498 ,  A61K31/4985 ,  A61K31/506 ,  A61K31/5377 ,  A61K45/06 ,  C07D241/42 ,  C07D241/44 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D405/04 ,  C07D405/14 ,  C07D407/04 ,  C07D407/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/12 ,  C07D471/04

Abstract: The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract translation: 本发明涉及新的喹喔啉衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法和所述化合物在治疗疾病中的用途。 癌症。