公开(公告)号：US09980973B2

公开(公告)日：2018-05-29

申请号：US15411463

申请日：2017-01-20

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Gianni Chessari ,  Christopher Norbert Johnson ,  Lee William Page ,  Thomas Daniel Heightman ,  Alessia Millemaggi ,  Steven Howard ,  Gordon Saxty

IPC: A61K31/553 ,  A61K31/5377 ,  A61K31/496 ,  A61K31/541 ,  A61K31/5375 ,  A61K31/551 ,  A61K31/506 ,  A61K31/4985 ,  A61K31/5025

CPC classification number: A61K31/553 ,  A61K31/496 ,  A61K31/4985 ,  A61K31/5025 ,  A61K31/506 ,  A61K31/5375 ,  A61K31/5377 ,  A61K31/541 ,  A61K31/551

Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.

公开(公告)号：US09617283B2

公开(公告)日：2017-04-11

申请号：US14436345

申请日：2013-10-18

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Gianni Chessari ,  Christopher Norbert Johnson ,  Lee William Page ,  Ildiko Maria Buck ,  James Edward Harvey Day ,  Steven Howard ,  Gordon Saxty ,  Christopher William Murray ,  Anna Hopkins

IPC: C07D403/14 ,  C07D471/04 ,  C07D487/04 ,  C07D519/00

CPC classification number: C07D519/00 ,  C07D403/14 ,  C07D471/04 ,  C07D487/04

Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.

公开(公告)号：US20150259359A1

公开(公告)日：2015-09-17

申请号：US14436345

申请日：2013-10-18

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Gianni Chessari ,  Christopher Norbert Johnson ,  Lee William Page ,  Ildiko Maria Buck ,  James Edward Harvey Day ,  Steven Howard ,  Gordon Saxty ,  Christopher William Murray ,  Anna Hopkins

IPC: C07D519/00 ,  C07D487/04 ,  C07D471/04

CPC classification number: C07D519/00 ,  C07D403/14 ,  C07D471/04 ,  C07D487/04

Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

公开(公告)号：US09663512B2

公开(公告)日：2017-05-30

申请号：US14436364

申请日：2013-10-18

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Gianni Chessari ,  Christopher Norbert Johnson ,  Lee William Page ,  Alessia Millemaggi ,  Steven Howard ,  Gordon Saxty ,  Thomas Daniel Heightman

IPC: C07D471/04 ,  C07D403/14 ,  C07D519/00 ,  C07D487/04

CPC classification number: C07D471/04 ,  C07D403/14 ,  C07D487/04 ,  C07D519/00

Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

公开(公告)号：US09617248B2

公开(公告)日：2017-04-11

申请号：US14436319

申请日：2013-10-18

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Gianni Chessari ,  Christopher Norbert Johnson ,  Lee William Page ,  Ildiko Maria Buck ,  James Edward Harvey Day ,  Steven Howard ,  Gordon Saxty ,  Christopher William Murray

IPC: C07D403/14 ,  C07D471/04 ,  C07D519/00

CPC classification number: C07D403/14 ,  C07D471/04 ,  C07D519/00

Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.

公开(公告)号：US20150266873A1

公开(公告)日：2015-09-24

申请号：US14436364

申请日：2013-10-18

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Gianni Chessari ,  Christopher Norbert Johnson ,  Lee William Page ,  Alessia Millemaggi ,  Steven Howard ,  Gordon Saxty ,  Thomas Daniel Heightman

IPC: C07D471/04 ,  C07D487/04

CPC classification number: C07D471/04 ,  C07D403/14 ,  C07D487/04 ,  C07D519/00

Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract translation: 本发明涉及新的双环杂环化合物，包含所述化合物的药物组合物和所述化合物在治疗疾病中的用途。 癌症。