-
公开(公告)号：US09493426B2
公开(公告)日：2016-11-15
申请号：US14787089
申请日：2014-04-25
Applicant: Astex Therapeutics Limited
Inventor： Patrick René Angibaud , Olivier Alexis Georges Querolle , Isabelle Noëlle Constance Pilatte , Lieven Meerpoel , Virginie Sophie Poncelet
IPC: C07D239/91 , A61K45/06 , A61K31/517 , C07D403/12 , C07D401/14 , C07D405/04 , C07D401/04 , C07D403/04 , C07D403/14 , C07D405/14
CPC classification number: C07D239/91 , A61K31/517 , A61K45/06 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/04 , C07D405/14
Abstract: The invention relates to new quinazolinone derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
-
![Substituted pyrido[2,3-b]pyrazines as FGFR kinase inhibitors](/abs-image/US/2016/04/12/US09309242B2/abs.jpg.150x150.jpg)
公开(公告)号：US09309242B2
公开(公告)日：2016-04-12
申请号：US14354832
申请日：2012-10-26
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Valerio Berdini , Gordon Saxty , Patrick Rene Angibaud , Olivier Alexis Georges Querolle , Virginie Sophie Poncelet , Bruno Roux , Lieven Meerpoel
IPC: A61K31/4985 , C07D241/36 , C07D471/04 , A61K31/506 , A61K31/5377
CPC classification number: A61K31/4985 , A61K31/506 , A61K31/5377 , C07D471/04
Abstract: The invention relates to new pyridopyrazine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Abstract translation: 本发明涉及新的吡啶并吡嗪衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法以及所述化合物在治疗疾病中的用途。 癌症。
-
公开(公告)号：US20140288053A1
公开(公告)日：2014-09-25
申请号：US14354832
申请日：2012-10-26
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Valerio Berdini , Gordon Saxty , Patrick Rene Angibaud , Olivier Alexis Georges Querolle , Virginie Sophie Poncelet , Bruno Roux , Lieven Meerpoel
IPC: C07D471/04 , A61K31/506 , A61K31/5377 , A61K31/4985
CPC classification number: A61K31/4985 , A61K31/506 , A61K31/5377 , C07D471/04
Abstract: The invention relates to new pyridopyrazine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Abstract translation: 本发明涉及新的吡啶并吡嗪衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法以及所述化合物在治疗疾病中的用途。 癌症。
-
Patent Agency Ranking
![Substituted pyrido[2,3-b]pyrazines as FGFR kinase inhibitors](/abs-image/US/2018/08/14/US10045982B2/abs.jpg.150x150.jpg)
公开(公告)号：US10045982B2
公开(公告)日：2018-08-14
申请号：US15019563
申请日：2016-02-09
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Valerio Berdini , Gordon Saxty , Patrick Rene Angibaud , Olivier Alexis Georges Querolle , Virginie Sophie Poncelet , Bruno Roux , Lieven Meerpoel
IPC: C07D471/04 , A61K31/4985 , A61K31/506 , A61K31/5377
CPC classification number: A61K31/4985 , A61K31/506 , A61K31/5377 , C07D471/04
Abstract: The invention relates to new pyridopyrazine derivative compounds of formula (I-A) or formula (I-B): to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
-
公开(公告)号：US20150031669A1
公开(公告)日：2015-01-29
申请号：US14354636
申请日：2012-10-26
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Steven John Woodhead , Christopher William Murray , Valerio Berdini , Gordon Saxty , Gilbert Ebai Besong , Lieven Meerpoel , Olivier Alexis Georges Querolle , Virginie Sophie Poncelet
IPC: C07D471/04 , A61K31/4985 , C07D403/04 , C07D405/14 , A61K45/06 , C07D241/42 , C07D413/04 , A61K31/506 , C07D405/04 , C07D417/04 , C07D401/04 , C07D401/14
CPC classification number: A61K31/498 , A61K31/4985 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D241/42 , C07D241/44 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D405/14 , C07D407/04 , C07D407/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/12 , C07D471/04
Abstract: The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Abstract translation: 本发明涉及新的喹喔啉衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法和所述化合物在治疗疾病中的用途。 癌症。
-
![Substituted pyrido[2,3-b]pyrazines as FGFR kinase inhibitors](/abs-image/US/2018/06/26/US10004733B2/abs.jpg.150x150.jpg)
公开(公告)号：US10004733B2
公开(公告)日：2018-06-26
申请号：US15019563
申请日：2016-02-09
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Valerio Berdini , Gordon Saxty , Patrick Rene Angibaud , Olivier Alexis Georges Querolle , Virginie Sophie Poncelet , Bruno Roux , Lieven Meerpoel
IPC: C07D471/04 , A61K31/4985 , A61K31/506 , A61K31/5377
Abstract: The invention relates to new pyridopyrazine derivative compounds of formula (I-A) or formula (I-B): to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
-
公开(公告)号：US10052320B2
公开(公告)日：2018-08-21
申请号：US15014156
申请日：2016-02-03
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Steven John Woodhead , Christopher William Murray , Valerio Berdini , Gordon Saxty , Gilbert Ebai Besong , Lieven Meerpoel , Olivier Alexis Georges Querolle , Virginie Sophie Poncelet
IPC: A61K31/498 , C07D241/40 , C07D403/12 , C07D401/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/06 , C07D407/04 , C07D407/14 , C07D413/04 , C07D417/04 , C07D241/42 , C07D241/44 , C07D417/12 , C07D471/04 , A61K31/4985 , A61K31/506 , A61K45/06 , C07D405/04 , C07D405/14 , A61K31/5377
CPC classification number: A61K31/498 , A61K31/4985 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D241/42 , C07D241/44 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D405/14 , C07D407/04 , C07D407/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/12 , C07D471/04
Abstract: The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
-
公开(公告)号：US09303029B2
公开(公告)日：2016-04-05
申请号：US14354636
申请日：2012-10-26
Applicant: ASTEX THERAPEUTICS LIMITED
Inventor： Steven John Woodhead , Christopher William Murray , Valerio Berdini , Gordon Saxty , Gilbert Ebai Besong , Lieven Meerpoel , Olivier Alexis Georges Querolle , Virginie Sophie Poncelet
IPC: A61K31/498 , C07D241/42 , C07D471/04 , C07D403/12 , C07D401/14 , C07D413/14 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/06 , C07D407/04 , C07D407/14 , C07D413/04 , C07D417/04 , C07D241/44 , C07D417/12 , A61K31/4985 , A61K31/506 , A61K45/06 , C07D405/04 , C07D405/14
CPC classification number: A61K31/498 , A61K31/4985 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D241/42 , C07D241/44 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/04 , C07D405/14 , C07D407/04 , C07D407/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/12 , C07D471/04
Abstract: The invention relates to new quinoxaline derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Abstract translation: 本发明涉及新的喹喔啉衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法和所述化合物在治疗疾病中的用途。 癌症。
-
-
-
-
-
-
-
Search Results
8
records
(took 0.026 seconds)
