专利检索 ap:("AURO PEPTIDES LTD" OR "Suresh Kumar Vadlamani" OR "Patil Nilesh Dagadu" OR "Shafee Mohammed Abdul" OR "Sanjay Devidas Patil" OR "Govindrajan Narayanan") AND inv:"Sanjay Devidas Patil" 第 1 页

1.

发明授权
Process for the preparation of linaclotide 有权

公开(公告)号：US11572386B2

公开(公告)日：2023-02-07

申请号：US15508928

申请日：2015-08-29

申请人： AURO PEPTIDES LTD , Suresh Kumar Vadlamani , Patil Nilesh Dagadu , Shafee Mohammed Abdul , Sanjay Devidas Patil , Govindrajan Narayanan

发明人： Suresh Kumar Vadlamani , Patil Nilesh Dagadu , Shafee Mohammed Abdul , Sanjay Devidas Patil , Govindrajan Narayanan

IPC分类号： C07K7/08 , B01D15/32 , B01D15/42

摘要： The present invention relates to a process for the preparation of Linaclotide by oxidizing linear Linaclotide of formula (II) using combination of air and oxidizing agent followed by purification using RP-HPLC.

2.

发明授权
Process for the preparation of liraglutide 有权

公开(公告)号：US10344069B2

公开(公告)日：2019-07-09

申请号：US15523384

申请日：2015-10-31

申请人： Auro Peptides Ltd , Suresh Kumar Vadlamani , Patil Nilesh Dagadu , Mohammed Abdul Shafee , Sanjay Devidas Patil , Nagana Goud Agasaladinni

发明人： Suresh Kumar Vadlamani , Patil Nilesh Dagadu , Mohammed Abdul Shafee , Sanjay Devidas Patil , Nagana Goud Agasaladinni

IPC分类号： C07K14/605

摘要： The present invention relates to a process for the preparation of Liraglutide, which comprises: a) synthesis of suitable fragments (protected) by solid phase peptide synthesis; b) coupling of the suitable fragments on solid support; c) concurrently cleaving the protected peptide from the solid support and de-protecting the peptide; d) purification of Liraglutide (crude) on reverse phase HPLC; e) isolating pure Liraglutide.

3.

发明申请
PROCESS FOR THE PREPARATION OF LIRAGLUTIDE 审中-公开

公开(公告)号：US20180251511A1

公开(公告)日：2018-09-06

申请号：US15523384

申请日：2015-10-31

申请人： Vadlamami SURESH KUMAR , Dagadu PATIL NILESH , Shafee MOHAMMED ABDUL , Patil SANJAY DEVIDAS , Agasaladinni NAGANAGOUD , AURO PEPTIDES LTD

发明人： Suresh Kumar Vadlamani , Patil Nilesh Dagadu , Mohammed Abdul Shafee , Sanjay Devidas Patil , Nagana Goud Agasaladinni

IPC分类号： C07K14/605

CPC分类号： C07K14/605

摘要： The present invention relates to a process for the preparation of Liraglutide, which comprises: a) synthesis of suitable fragments (protected) by solid phase peptide synthesis; b) coupling of the suitable fragments on solid support; c) concurrently cleaving the protected peptide from the solid support and de-protecting the peptide; d) purification of Liraglutide (crude) on reverse phase HPLC; e) isolating pure Liraglutide.

4.

发明申请
A PROCESS FOR THE PREPARATION OF LINACLOTIDE 审中-公开

公开(公告)号：US20170240599A1

公开(公告)日：2017-08-24

申请号：US15508928

申请日：2015-08-29

申请人： Vadlamani SURESH KUMAR , Dagadu PATIL NILESH , Shafee MOHAMMED ABDUL , Patil SANJAY DEVIDAS , Narayanan GOVINDARAJAN , AURO PEPTIDES LTD

发明人： Suresh Kumar Vadlamani , Patil Nilesh Dagadu , Shafee Mohammed Abdul , Sanjay Devidas Patil , Govindrajan Narayanan

IPC分类号： C07K7/08 , B01D15/42 , B01D15/32

CPC分类号： C07K7/08 , B01D15/325 , B01D15/426

摘要： The present invention relates to a process for the preparation of Linaclotide by oxidizing linear Linaclotide of formula (II) using combination of air and oxidizing agent followed by purification using RP-HPLC.