Cell-based biosensor array and associated methods for manufacturing the same

    公开(公告)号:US10067117B2

    公开(公告)日:2018-09-04

    申请号:US14825140

    申请日:2015-08-12

    Abstract: A cell-based biosensor array includes a base plate having a plurality of substantially transparent areas. The cell-based biosensor array also includes a flexible substrate coupled to the base plate and having disposed thereon a plurality of electrode sets, a plurality of terminal contacts, and a plurality of conductive traces. Each electrode set is disposed proximate a respective one of the substantially transparent areas, and each electrode set includes at least one electrode configured to detect an electric signal. Each terminal contact is associated with a respective one of the at least one electrode and disposed proximate a perimeter of the flexible substrate. Each conductive trace is electrically coupling a respective at least one electrode to the corresponding terminal contact. A first portion of flexible substrate including the electrode sets is disposed on a first surface of the base plate. A second portion of the flexible substrate including the terminal contacts is disposed on a second surface of the base plate.

    CELL-BASED BIOSENSOR ARRAY AND ASSOCIATED METHODS FOR MANUFACTURING THE SAME
    5.
    发明申请
    CELL-BASED BIOSENSOR ARRAY AND ASSOCIATED METHODS FOR MANUFACTURING THE SAME 审中-公开
    基于细胞的生物传感器阵列及其相关方法制造方法

    公开(公告)号:US20160047770A1

    公开(公告)日:2016-02-18

    申请号:US14825140

    申请日:2015-08-12

    CPC classification number: G01N33/4836 B01L3/5085

    Abstract: A cell-based biosensor array includes a base plate having a plurality of substantially transparent areas. The cell-based biosensor array also includes a flexible substrate coupled to the base plate and having disposed thereon a plurality of electrode sets, a plurality of terminal contacts, and a plurality of conductive traces. Each electrode set is disposed proximate a respective one of the substantially transparent areas, and each electrode set includes at least one electrode configured to detect an electric signal. Each terminal contact is associated with a respective one of the at least one electrode and disposed proximate a perimeter of the flexible substrate. Each conductive trace is electrically coupling a respective at least one electrode to the corresponding terminal contact. A first portion of flexible substrate including the electrode sets is disposed on a first surface of the base plate. A second portion of the flexible substrate including the terminal contacts is disposed on a second surface of the base plate.

    Abstract translation: 基于细胞的生物传感器阵列包括具有多个基本透明区域的基板。 基于细胞的生物传感器阵列还包括耦合到基板并且在其上设置有多个电极组,多个端子触点和多个导电迹线的柔性基板。 每个电极组被设置在基本上透明区域中的相应一个附近,并且每个电极组包括配置成检测电信号的至少一个电极。 每个端子触点与所述至少一个电极中的相应的一个相关联并且设置在柔性基板的周边附近。 每个导电迹线将相应的至少一个电极电耦合到相应的端子触点。 包括电极组的柔性基板的第一部分设置在基板的第一表面上。 包括端子触头的柔性基板的第二部分设置在基板的第二表面上。

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