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公开(公告)号:US20090181380A1
公开(公告)日:2009-07-16
申请号:US12158262
申请日:2006-12-19
申请人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquin , Helene Fournier , Quynh Nguyen-Huu , Pascal Croteau , Rene Allard , Sandie Briand , Paul Van Eerdewegh , Randall David Little , Jonathan Segal , Tim Keith
发明人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquin , Helene Fournier , Quynh Nguyen-Huu , Pascal Croteau , Rene Allard , Sandie Briand , Paul Van Eerdewegh , Randall David Little , Jonathan Segal , Tim Keith
CPC分类号: C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , Y02A90/26
摘要: The present invention relates to the selection of a set of polymorphism makers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to IBD (ex: Chrohn's disease) and/or their response to a particular drug or drugs.
摘要翻译: 本发明涉及一组基于连锁不平衡映射的基因组广泛关联研究中使用的多态性制造者的选择。 特别地,本发明涉及药物基因组学,诊断学,患者治疗和使用遗传单体型信息来预测个体对IBD(例如:克罗恩病)的易感性和/或其对特定药物或药物的反应的领域。
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公开(公告)号:US20090081658A1
公开(公告)日:2009-03-26
申请号:US12064797
申请日:2006-08-24
申请人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquin , Helene Fournier , Quynh Nguyen-Huu , Pascal Croteau , Rene Allard , Sophie Debrus , Valerie Serre , Paul Van Eerdewegh , Randall David Little , Tim Keith , Jonathan Segal , Tim Keith
发明人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquin , Helene Fournier , Quynh Nguyen-Huu , Pascal Croteau , Rene Allard , Sophie Debrus , Valerie Serre , Paul Van Eerdewegh , Randall David Little , Tim Keith , Jonathan Segal , Tim Keith
CPC分类号: C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要: The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to Crohn's disease and/or their response to a particular drug or drugs.
摘要翻译: 本发明涉及用于基于连锁不平衡作图的基因组广泛关联研究中使用的一组多态性标记物的选择。 特别地,本发明涉及药物基因组学,诊断学,患者治疗和使用遗传单倍型信息来预测个体对克罗恩病的易感性和/或其对特定药物或药物的反应的领域。
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公开(公告)号:US20090305900A1
公开(公告)日:2009-12-10
申请号:US11917896
申请日:2006-06-19
申请人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquin , Quynh Nguyen-Huu , Pascal Croteau , Rene Allard , Johanne Cousineau , Nouzha Paquin , Paul Van Eerdewegh , Randall David Little , Tim Keith , Jonathan Segal
发明人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquin , Quynh Nguyen-Huu , Pascal Croteau , Rene Allard , Johanne Cousineau , Nouzha Paquin , Paul Van Eerdewegh , Randall David Little , Tim Keith , Jonathan Segal
CPC分类号: C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要: The present invention relates to the selection of a set of SNP markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's longevity, their protection against age-related diseases and/or their response to a particular drug or drugs.
摘要翻译: 本发明涉及用于基于连锁不平衡作图的基因组广泛关联研究中使用的一组SNP标记物的选择。 特别地,本发明涉及药物基因组学,诊断学,患者治疗以及使用遗传单倍体信息来预测个体的寿命,其对年龄相关疾病的保护和/或其对特定药物或药物的反应的领域。
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公开(公告)号:US20100081129A1
公开(公告)日:2010-04-01
申请号:US11919503
申请日:2006-05-01
申请人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquin , Hélene Fournier , Quynh Nguyen-Huu , Pascal Croteau , Réne Allard , Sophie Debrus , Valerie Serre , Paul Van Eerdewegh , Randall David Little , Jonathan Segal , Tim Keith
发明人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquin , Hélene Fournier , Quynh Nguyen-Huu , Pascal Croteau , Réne Allard , Sophie Debrus , Valerie Serre , Paul Van Eerdewegh , Randall David Little , Jonathan Segal , Tim Keith
IPC分类号: C12Q1/68
CPC分类号: G01N33/5023 , A61K48/00 , A61K49/0404 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , G01N33/6893 , G01N2800/065 , G01N2800/52
摘要: The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to Crohn's disease and/or their response to a particular drug or drugs.
摘要翻译: 本发明涉及用于基于连锁不平衡作图的基因组广泛关联研究中使用的一组多态性标记物的选择。 特别地,本发明涉及药物基因组学,诊断学,患者治疗和使用遗传单倍型信息来预测个体对克罗恩病的易感性和/或其对特定药物或药物的反应的领域。
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公开(公告)号:US20100120627A1
公开(公告)日:2010-05-13
申请号:US12309878
申请日:2006-08-02
申请人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquian , Quynh Nguyen-Huu , Pascal Croteau , Rene Allard , Randall David Little , Johanne Cousineau , Sophie Debrus , Tim Keith , Natali Henderson , Daniel Dubois , Paul Van Eerdewegh , Jonathan Segal
发明人: Abdelmajid Belouchi , John Verner Raelson , Walter Edward Bradley , Bruno Paquian , Quynh Nguyen-Huu , Pascal Croteau , Rene Allard , Randall David Little , Johanne Cousineau , Sophie Debrus , Tim Keith , Natali Henderson , Daniel Dubois , Paul Van Eerdewegh , Jonathan Segal
CPC分类号: C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要: The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to psoriasis disease and/or their response to a particular drug or drugs.
摘要翻译: 本发明涉及用于基于连锁不平衡作图的基因组广泛关联研究中使用的一组多态性标记物的选择。 特别地,本发明涉及药物基因组学,诊断学,患者治疗以及使用遗传单倍型信息来预测个体对牛皮癣疾病易感性和/或其对特定药物或药物的反应的领域。
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