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公开(公告)号:US20220265140A1
公开(公告)日:2022-08-25
申请号:US17662054
申请日:2022-05-04
Applicant: ACUCELA INC.
Inventor: Christian OGGENFUSS , Karim HAROUD , Lukas SCHEIBLER , Matthias PFISTER , Urban SCHNELL , Stefan TROLLER , Ryo KUBOTA , Philip M. BUSCEMI
Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
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公开(公告)号:US20240225440A1
公开(公告)日:2024-07-11
申请号:US18615043
申请日:2024-03-25
Applicant: ACUCELA INC.
Inventor: Ryo KUBOTA , Stephan WYDER , Philip M. BUSCEMI , Matthias PFISTER , Cyril STOLLER
IPC: A61B3/10 , G01B9/02091
CPC classification number: A61B3/102 , G01B9/02091
Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. Measurement data may be processed using a decurving process to enhance the resolution of the ILM layer and provide improved determinations of retinal thickness.
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3.
公开(公告)号:US20230210360A1
公开(公告)日:2023-07-06
申请号:US18177993
申请日:2023-03-03
Applicant: ACUCELA INC.
Inventor: Lukas SCHEIBLER , Matthias PFISTER , Urban SCHNELL , Stefan TROLLER , Ryo KUBOTA
CPC classification number: A61B3/102 , A61B3/1005 , A61B3/0008 , A61B3/0025 , A61B3/1225 , A61B5/0013 , G01B9/02 , A61B3/10 , A61B2576/00 , A61B2560/0431 , A61B2505/07 , A61B2560/0425 , A61B2560/0456
Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
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公开(公告)号:US20220301161A1
公开(公告)日:2022-09-22
申请号:US17805299
申请日:2022-06-03
Applicant: ACUCELA INC.
Inventor: Stephan WYDER , Matthias PFISTER , Cyril STOLLER , Philip M. BUSCEMI
Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.
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公开(公告)号:US20230110912A1
公开(公告)日:2023-04-13
申请号:US18064422
申请日:2022-12-12
Applicant: ACUCELA INC.
Inventor: Christian OGGENFUSS , Karim HAROUD , Lukas SCHEIBLER , Matthias PFISTER , Urban SCHNELL , Stefan TROLLER , Ryo KUBOTA , Philip BUSCEMI
Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
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公开(公告)号:US20230026753A1
公开(公告)日:2023-01-26
申请号:US17936263
申请日:2022-09-28
Applicant: ACUCELA INC.
Inventor: Ryo KUBOTA , Philip M. BUSCEMI , Matthias PFISTER , Stephan WYDER , Amitava GUPTA
IPC: A61B3/10 , G01B9/02091
Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).
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公开(公告)号:US20220304573A1
公开(公告)日:2022-09-29
申请号:US17647585
申请日:2022-01-10
Applicant: ACUCELA INC.
Inventor: Ryo KUBOTA , Philip M. BUSCEMI , Matthias PFISTER , Stephan WYDER , Amitava GUPTA
IPC: A61B3/10 , G01B9/02091
Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).
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8.
公开(公告)号:US20180271363A1
公开(公告)日:2018-09-27
申请号:US15996329
申请日:2018-06-01
Applicant: Acucela Inc.
Inventor: Lukas SCHEIBLER , Matthias PFISTER , Urban SCHNELL , Stefan TROLLER , Ryo KUBOTA
CPC classification number: A61B3/102 , A61B3/0008 , A61B3/0025 , A61B3/10 , A61B3/1005 , A61B3/1225 , A61B5/0013 , A61B2505/07 , A61B2560/0425 , A61B2560/0431 , A61B2560/0456 , A61B2576/00 , G01B9/02
Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
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9.
公开(公告)号:US20240023805A1
公开(公告)日:2024-01-25
申请号:US18475666
申请日:2023-09-27
Applicant: ACUCELA INC.
Inventor: Christian OGGENFUSS , Karim HAROUD , Lukas SCHEIBLER , Matthias PFISTER , Urban SCHNELL , Stefan TROLLER , Ryo KUBOTA , Philip M. BUSCEMI
CPC classification number: A61B3/102 , A61B3/0008 , A61B3/1005 , A61B3/132 , A61B2560/0431 , A61B2562/0214 , A61B2562/0257 , A61B2562/223
Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
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公开(公告)号:US20230414097A1
公开(公告)日:2023-12-28
申请号:US18452350
申请日:2023-08-18
Applicant: ACUCELA INC.
Inventor: Ryo KUBOTA , Philip M. BUSCEMI , Matthias PFISTER , Stephan WYDER , Amitava GUPTA
IPC: A61B3/10 , G01B9/02091
CPC classification number: A61B3/102 , G01B9/02091 , G01B2290/45
Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).
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