公开(公告)号：US08759055B2

公开(公告)日：2014-06-24

申请号：US12020459

申请日：2008-01-25

申请人： Adam Heller ,  Nicholas Mano ,  Hyug-Han Kim ,  Yongchao Zhang ,  Fei Mao ,  Ting Chen ,  Scott C. Barton

发明人： Adam Heller ,  Nicholas Mano ,  Hyug-Han Kim ,  Yongchao Zhang ,  Fei Mao ,  Ting Chen ,  Scott C. Barton

IPC分类号： C12N11/18 ,  C12Q1/26 ,  C12Q1/32 ,  G01N33/72 ,  H01M8/16

CPC分类号： H01M8/16 ,  C12Q1/26 ,  C12Q1/32 ,  G01N33/723 ,  Y02E60/527

摘要： A fuel cell is provided with an anode and a cathode. The anode is in electrical communication with an anode enzyme and the cathode is in electrical communication with a cathode enzyme. The anode enzyme is preferably an oxidase or a dehydrogenase. The cathode enzyme is a copper-containing enzyme, such as a lacasse, an ascorbate oxidase, a ceruloplasmine, or a bilirubin oxidase. Preferably, the cathode enzyme is operable under physiological conditions. Redox polymers serve to wire the anode enzyme to the anode and the cathode enzyme to the cathode. The fuel cell can be very small in size because it does not require a membrane, seal, or case. The fuel cell can be used in connection with a biological system, such as a human, as it may operate at physiological conditions. By virtue of its size and operability at physiological conditions, the fuel cell is of particular interest for applications calling for a power source implanted in a human body, such as a variety of medical applications.

摘要翻译： 燃料电池设有阳极和阴极。 阳极与阳极酶电连通，阴极与阴极酶电连通。 阳极酶优选为氧化酶或脱氢酶。 阴极酶是含铜酶，例如lacasse，抗坏血酸氧化酶，血清白蛋白或胆红素氧化酶。 优选地，阴极酶在生理条件下是可操作的。 氧化还原聚合物用于将阳极酶连接到阳极，阴极酶连接到阴极。 燃料电池的尺寸可以非常小，因为它不需要膜，密封件或外壳。 燃料电池可以与诸如人类的生物系统结合使用，因为其可以在生理条件下操作。 由于其在生理条件下的尺寸和可操作性，燃料电池对于要求植入人体的电源（例如各种医疗应用）的应用是特别有意义的。

公开(公告)号：US20080044721A1

公开(公告)日：2008-02-21

申请号：US10427113

申请日：2003-05-01

申请人： Adam Heller ,  Nicholas Mano ,  Hyug-Han Kim ,  Yongchao Zhang ,  Fei Mao ,  Ting Chen ,  Scott Calabrese Barton

发明人： Adam Heller ,  Nicholas Mano ,  Hyug-Han Kim ,  Yongchao Zhang ,  Fei Mao ,  Ting Chen ,  Scott Calabrese Barton

IPC分类号： H01M4/90 ,  C12Q1/00

CPC分类号： H01M8/16 ,  C12Q1/26 ,  C12Q1/32 ,  G01N33/723 ,  Y02E60/527

摘要： A fuel cell is provided with an anode and a cathode. The anode is in electrical communication with an anode enzyme and the cathode is in electrical communication with a cathode enzyme. The anode enzyme is preferably an oxidase or a dehydrogenase. The cathode enzyme is a copper-containing enzyme, such as a laccase, an ascorbate oxidase, a ceruloplasmine, or a bilirubin oxidase. Preferably, the cathode enzyme is operable under physiological conditions. Redox polymers serve to wire the anode enzyme to the anode and the cathode enzyme to the cathode. The fuel cell can be very small in size because it does not require a membrane, seal, or case. The fuel cell can be used in connection with a biological system, such as a human, as it may operate at physiological conditions. By virtue of its size and operability at physiological conditions, the fuel cell is of particular interest for applications calling for a power source implanted in a human body, such as a variety of medical applications.

摘要翻译： 燃料电池设有阳极和阴极。 阳极与阳极酶电连通，阴极与阴极酶电连通。 阳极酶优选为氧化酶或脱氢酶。 阴极酶是含铜酶，例如漆酶，抗坏血酸氧化酶，血清白蛋白或胆红素氧化酶。 优选地，阴极酶在生理条件下是可操作的。 氧化还原聚合物用于将阳极酶连接到阳极，阴极酶连接到阴极。 燃料电池的尺寸可以非常小，因为它不需要膜，密封件或外壳。 燃料电池可以与诸如人类的生物系统结合使用，因为其可以在生理条件下操作。 由于其在生理条件下的尺寸和可操作性，燃料电池对于要求植入人体的电源（例如各种医疗应用）的应用是特别有意义的。

公开(公告)号：US20080118782A1

公开(公告)日：2008-05-22

申请号：US12020459

申请日：2008-01-25

申请人： ADAM HELLER ,  Nicholas Mano ,  Hyug-Han Kim ,  Yongchao Zhang ,  Fei Mao ,  Ting Chen ,  Scott Barton

发明人： ADAM HELLER ,  Nicholas Mano ,  Hyug-Han Kim ,  Yongchao Zhang ,  Fei Mao ,  Ting Chen ,  Scott Barton

IPC分类号： H01M8/16

CPC分类号： H01M8/16 ,  C12Q1/26 ,  C12Q1/32 ,  G01N33/723 ,  Y02E60/527

摘要： A fuel cell is provided with an anode and a cathode. The anode is in electrical communication with an anode enzyme and the cathode is in electrical communication with a cathode enzyme. The anode enzyme is preferably an oxidase or a dehydrogenase. The cathode enzyme is a copper-containing enzyme, such as a lacasse, an ascorbate oxidase, a ceruloplasmine, or a bilirubin oxidase. Preferably, the cathode enzyme is operable under physiological conditions. Redox polymers serve to wire the anode enzyme to the anode and the cathode enzyme to the cathode. The fuel cell can be very small in size because it does not require a membrane, seal, or case. The fuel cell can be used in connection with a biological system, such as a human, as it may operate at physiological conditions. By virtue of its size and operability at physiological conditions, the fuel cell is of particular interest for applications calling for a power source implanted in a human body, such as a variety of medical applications.

摘要翻译： 燃料电池设有阳极和阴极。 阳极与阳极酶电连通，阴极与阴极酶电连通。 阳极酶优选为氧化酶或脱氢酶。 阴极酶是含铜酶，例如lacasse，抗坏血酸氧化酶，血清白蛋白或胆红素氧化酶。 优选地，阴极酶在生理条件下是可操作的。 氧化还原聚合物用于将阳极酶连接到阳极，阴极酶连接到阴极。 燃料电池的尺寸可以非常小，因为它不需要膜，密封件或外壳。 燃料电池可以与诸如人类的生物系统结合使用，因为其可以在生理条件下操作。 由于其在生理条件下的尺寸和可操作性，燃料电池对于要求植入人体的电源（例如各种医疗应用）的应用是特别有意义的。

公开(公告)号：US07368190B2

公开(公告)日：2008-05-06

申请号：US10427113

申请日：2003-05-01

申请人： Adam Heller ,  Nicholas Mano ,  Hyug-Han Kim ,  Yongchao Zhang ,  Fei Mao ,  Ting Chen ,  Scott Calabrese Barton

发明人： Adam Heller ,  Nicholas Mano ,  Hyug-Han Kim ,  Yongchao Zhang ,  Fei Mao ,  Ting Chen ,  Scott Calabrese Barton

IPC分类号： H01M8/16

CPC分类号： H01M8/16 ,  C12Q1/26 ,  C12Q1/32 ,  G01N33/723 ,  Y02E60/527

摘要： A fuel cell is provided with an anode and a cathode. The anode is in electrical communication with an anode enzyme and the cathode is in electrical communication with a cathode enzyme. The anode enzyme is preferably an oxidase or a dehydrogenase. The cathode enzyme is a copper-containing enzyme, such as a laccase, an ascorbate oxidase, a ceruloplasmine, or a bilirubin oxidase. Preferably, the cathode enzyme is operable under physiological conditions. Redox polymers serve to wire the anode enzyme to the anode and the cathode enzyme to the cathode. The fuel cell can be very small in size because it does not require a membrane, seal, or case. The fuel cell can be used in connection with a biological system, such as a human, as it may operate at physiological conditions. By virtue of its size and operability at physiological conditions, the fuel cell is of particular interest for applications calling for a power source implanted in a human body, such as a variety of medical applications.

摘要翻译： 燃料电池设有阳极和阴极。 阳极与阳极酶电连通，阴极与阴极酶电连通。 阳极酶优选为氧化酶或脱氢酶。 阴极酶是含铜酶，例如漆酶，抗坏血酸氧化酶，血清白蛋白或胆红素氧化酶。 优选地，阴极酶在生理条件下是可操作的。 氧化还原聚合物用于将阳极酶连接到阳极，阴极酶连接到阴极。 燃料电池的尺寸可以非常小，因为它不需要膜，密封件或外壳。 燃料电池可以与诸如人类的生物系统结合使用，因为其可以在生理条件下操作。 由于其在生理条件下的尺寸和可操作性，燃料电池对于要求植入人体的电源（例如各种医疗应用）的应用是特别有意义的。