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1.发明授权公开(公告)号：US10016517B2
公开(公告)日：2018-07-10
申请号：US14237974
申请日：2012-08-08
IPC分类号： A61K9/14 , A61K49/00 , G01N33/92 , A61L27/18 , A61L27/54 , A61L29/16 , A61L31/16 , A61K9/51 , A61K47/54 , A61K47/64 , A61K47/69
CPC分类号： A61K49/0093 , A61K9/14 , A61K9/141 , A61K9/51 , A61K9/513 , A61K47/542 , A61K47/6425 , A61K47/6907 , A61K49/0082 , A61L27/18 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/44 , A61L2300/442 , A61L2300/624 , A61L2400/12 , G01N33/92 , C08L71/02
摘要： The present invention relates to nanoparticle compositions and treatment of cardiovascular disease using nanoparticles to target Class A and B scavenger receptors. This invention further relates to methods of detecting cells that express scavenger receptors, detecting atherosclerotic lesions, and targeting bioactive amphiphilic macromolecules to cells that express scavenger receptors.
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2.发明申请BIOACTIVE AMPHIPHILIC POLYMER STABILIZED NANOPARTICLES WITH ENHANCED STABILITY AND ACTIVITY 有权具有增强稳定性和活性的生物活性聚合物稳定纳米颗粒公开(公告)号：US20140328763A1
公开(公告)日：2014-11-06
申请号：US14237974
申请日：2012-08-08
CPC分类号： A61K49/0093 , A61K9/14 , A61K9/141 , A61K9/51 , A61K9/513 , A61K47/542 , A61K47/6425 , A61K47/6907 , A61K49/0082 , A61L27/18 , A61L27/54 , A61L29/16 , A61L31/16 , A61L2300/44 , A61L2300/442 , A61L2300/624 , A61L2400/12 , G01N33/92 , C08L71/02
摘要： The present invention relates to nanoparticle compositions and treatment of cardiovascular disease using nanoparticles to target Class A and B scavenger receptors. This invention further relates to methods of detecting cells that express scavenger receptors, detecting atherosclerotic lesions, and targeting bioactive amphiphilic macromolecules to cells that express scavenger receptors.
摘要翻译： 本发明涉及纳米颗粒组合物和使用纳米颗粒靶向A类和B类清道夫受体的心血管疾病的治疗。 本发明进一步涉及检测表达清道夫受体，检测动脉粥样硬化病变和将生物活性两亲性大分子靶向表达清道夫受体的细胞的细胞的方法。
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