公开(公告)号：US20140170224A1

公开(公告)日：2014-06-19

申请号：US14103421

申请日：2013-12-11

Applicant: Agency for Science, Technology and Research

Inventor： Jun Li ,  Zhongxing Zhang ,  Chengde Liu

IPC: A61K9/14 ,  A61K36/00 ,  A61K35/12

CPC classification number: A61K36/00 ,  A61K9/5057 ,  A61K9/5089 ,  A61K35/12 ,  A61L27/222 ,  A61L27/38 ,  A61L27/52 ,  A61L27/54 ,  A61L2300/64

Abstract: A gelatin-based microgel was prepared by a simple method starting from gelatin and alginate. The microgel was composed of a soft gelatin-based core coated by a permeable membrane. Gelatin-based core was moderately crosslinked by a novel crosslinker 4-arm PEG succinimidyl glutarate (pentaerytheritol core) (sPEG-4A-GS(10 k)).

Abstract translation: 通过从明胶和藻酸盐开始的简单方法制备明胶基微凝胶。 微凝胶由用透明膜包覆的软明胶核组成。 明胶基核心通过新的交联剂4-臂PEG琥珀酰亚胺基戊二酸酯（季戊四醇核心）（sPEG-4A-GS（10k））中等交联。