公开(公告)号：US10883978B2

公开(公告)日：2021-01-05

申请号：US15421173

申请日：2017-01-31

Applicant: Agilent Technologies, Inc.

Inventor： Andrew C. Neilson

IPC: G01N33/497 ,  B01D63/08 ,  B01D69/10 ,  B01L3/00

Abstract: An apparatus for calibrating a flux analyzer comprises a first frame; a second frame; and a permeable membrane. The first frame and the second frame are connected or integrally formed. A method for calibrating a flux analyzer is provided which uses an artificial standard rather than a biological standard.

公开(公告)号：US20230256435A1

公开(公告)日：2023-08-17

申请号：US18164422

申请日：2023-02-03

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Andrew C. Neilson ,  Jason Dell'Arciprete ,  Eric John Schultz ,  Brady Robert Paradis ,  George W. Rogers ,  Yoonseok Kam

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L2400/0487 ,  B01L2200/10 ,  B01L2200/147

Abstract: An analytical instrument having a sensing system, a stage adapted to receive a sample carrier, a motion actuator assembly for positioning the sensing system and/or the stage, a temperature control element, and a signal processing module are disclosed. Methods of analyzing cell samples with the analytical instrument are also disclosed.

公开(公告)号：US20180217126A1

公开(公告)日：2018-08-02

申请号：US15421173

申请日：2017-01-31

Applicant: Agilent Technologies, Inc.

Inventor： Andrew C. Neilson

IPC: G01N33/497 ,  B01L3/00

Abstract: An apparatus for calibrating a flux analyzer comprises a first frame; a second frame; and a permeable membrane. The first frame and the second frame are connected or integrally formed. A method for calibrating a flux analyzer is provided which uses an artificial standard rather than a biological standard.

公开(公告)号：US20240409864A1

公开(公告)日：2024-12-12

申请号：US18701642

申请日：2022-11-04

Applicant: Agilent Technologies, Inc.

Inventor： Chong Wing Yung ,  Smruti Madan Phadnis ,  Andrew C. Neilson ,  Hien Vuong Cheung

IPC: C12M1/32 ,  C12M1/00 ,  C12M1/34 ,  C12M3/00

Abstract: An apparatus for containing a three-dimensional cellular material surrounded by a medium that facilitates and maintains the centering of the three-dimensional cellular material throughout an assay is provided. The apparatus includes a well having an open proximal end and a closed distal end. Further, the well defines a compartment having an interior surface and a sample nesting site for containing the three-dimensional cellular material surrounded by the medium. A central indentation is located at the closed distal end of the well, a first concentric lip is located above the central indentation in a y-direction towards the open proximal end of the well, and a second concentric lip is located above the first concentric lip in the y-direction towards the open proximal end of the well. Additionally, the first concentric lip and the second concentric lip define a groove therebetween. A method of forming a three-dimensional cellular material is also provided.

公开(公告)号：US20230228743A1

公开(公告)日：2023-07-20

申请号：US18126809

申请日：2023-03-27

Applicant: Agilent Technologies, Inc.

Inventor： Andrew C. Neilson ,  Paul D. McGarr

IPC: G01N33/53 ,  G01N21/03 ,  G01N21/64 ,  C12M1/34 ,  B01L3/00

CPC classification number: G01N33/5302 ,  G01N21/03 ,  G01N21/6452 ,  C12M41/46 ,  B01L3/50853 ,  G01N33/5304 ,  G01N2021/0325 ,  B01L2300/0829 ,  B01L2300/0627 ,  B01L2300/0609

Abstract: The present disclosure relates to methods and apparatus for measuring of multiple physiological properties of biological samples, such as measuring biological flux.