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公开(公告)号：US08697125B2
公开(公告)日：2014-04-15
申请号：US12449256
申请日：2008-01-30
申请人： Akihiko Ono , Shigeyuki Marunaka , Makoto Fukuta
发明人： Akihiko Ono , Shigeyuki Marunaka , Makoto Fukuta
IPC分类号： A61K9/20 , A61K31/717 , A61K31/047 , A61K31/505 , A61K31/7004
CPC分类号： A61K31/513 , A61K9/2054
摘要： The present invention provides a tablet without causing a tableting trouble, which is superior in the tablet formability, dissolution property of pharmaceutically active ingredient, and the like.
摘要翻译： 本发明提供一种片剂，不会引起片剂成型性，药物活性成分的溶解性等优异的压片麻烦。
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公开(公告)号：US20090318482A1
公开(公告)日：2009-12-24
申请号：US12449256
申请日：2008-01-30
申请人： Akihiko Ono , Shigeyuki Marunaka , Makoto Fukuta
发明人： Akihiko Ono , Shigeyuki Marunaka , Makoto Fukuta
IPC分类号： A61K31/513 , A61P43/00
CPC分类号： A61K31/513 , A61K9/2054
摘要： The present invention provides a tablet without causing a tableting trouble, which is superior in the tablet formability, dissolution property of pharmaceutically active ingredient, and the like.
摘要翻译： 本发明提供一种片剂，不会引起片剂成型性，药物活性成分的溶解性等优异的压片麻烦。
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公开(公告)号：US20090036522A1
公开(公告)日：2009-02-05
申请号：US11922769
申请日：2006-06-21
申请人： Shigeyuki Marunaka , Makoto Fukuta
发明人： Shigeyuki Marunaka , Makoto Fukuta
IPC分类号： A61K31/343
CPC分类号： A61K9/2054 , A61K9/284 , A61K9/2866 , A61K31/407
摘要： A tablet showing regulated variation in dissolution from lot to lot which contains from about 3 to about 50% by weight (w/w), based on the whole tablet, of (S)—N—[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide, magnesium stearate and hydroxypropylcellulose having a viscosity of about 1 to about 4 mPa·s.
摘要翻译： 基于全片，含有约3至约50重量％（w / w）的（S）-N- [2-（1,6,7 ，8-四氢-2H-茚并[5,4-b]呋喃-8-基）乙基]丙酰胺，硬脂酸镁和粘度为约1至约4mPa.s.的羟丙基纤维素。
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公开(公告)号：US20120115837A1
公开(公告)日：2012-05-10
申请号：US13138950
申请日：2010-04-28
IPC分类号： A61K31/397 , A61K31/4245 , A61P9/12 , A61K31/444 , A61K31/496 , A61K31/416 , A61K31/4418
CPC分类号： A61K31/496 , A61K31/397 , A61K31/416 , A61K31/4245 , A61K31/4418 , A61K31/444 , A61K45/06 , A61K2300/00
摘要： Provided is a solid preparation comprising (i) a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof, (ii) a sugar alcohol, and (iii) a calcium antagonist, which is superior in the dissolution property and stability.
摘要翻译： 提供一种固体制剂，其包含（i）由式（I）表示的化合物：其中每个符号如说明书中所定义，或其盐，（ii）糖醇和（iii）钙拮抗剂，其中 溶解性和稳定性优越。
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公开(公告)号：US08821926B2
公开(公告)日：2014-09-02
申请号：US11922769
申请日：2006-06-21
申请人： Shigeyuki Marunaka , Makoto Fukuta
发明人： Shigeyuki Marunaka , Makoto Fukuta
CPC分类号： A61K9/2054 , A61K9/284 , A61K9/2866 , A61K31/407
摘要： A tablet showing regulated variation in dissolution from lot to lot which contains from about 3 to about 50% by weight (w/w), based on the whole tablet, of (S)—N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide, magnesium stearate and hydroxypropylcellulose having a viscosity of about 1 to about 4 mPa·s.
摘要翻译： 基于全片，含有约3至约50重量％（w / w）的（S）-N- [2-（1,6,7 ，8-四氢-2H-茚并[5,4-b]呋喃-8-基）乙基]丙酰胺，硬脂酸镁和粘度约1至约4mPa·s的羟丙基纤维素。
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公开(公告)号：US08541024B2
公开(公告)日：2013-09-24
申请号：US13063515
申请日：2009-09-15
IPC分类号： A61K9/20
CPC分类号： A61K9/282 , A61J3/005 , A61K9/2072 , A61K31/4245 , A61K31/513 , A61K31/553
摘要： A film-coated scored tablet in which the forms of respective parts associated with a score line are optimized so as to more preferably divide the film along the score line is provided.
摘要翻译： 提供了一种薄膜涂抹的刻痕片，其中优化与刻痕线相关联的各部分的形式，以便更优选地沿着刻痕线划分膜。
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公开(公告)号：US20110244040A1
公开(公告)日：2011-10-06
申请号：US13063515
申请日：2009-09-15
IPC分类号： A61K9/28 , A61K31/506 , A61K31/4245
CPC分类号： A61K9/282 , A61J3/005 , A61K9/2072 , A61K31/4245 , A61K31/513 , A61K31/553
摘要： A film-coated scored tablet in which the forms of respective parts associated with a score line are optimized so as to more preferably divide the film along the score line is provided.
摘要翻译： 提供了一种薄膜涂抹的刻痕片，其中优化与刻痕线相关联的各部分的形式，以便更优选地沿着刻痕线划分膜。
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8.发明申请公开(公告)号：US20070116764A1
公开(公告)日：2007-05-24
申请号：US10581071
申请日：2004-11-30
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
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9.发明授权公开(公告)号：US09149437B2
公开(公告)日：2015-10-06
申请号：US12659630
申请日：2010-03-15
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
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10.发明申请公开(公告)号：US20110014130A1
公开(公告)日：2011-01-20
申请号：US12659630
申请日：2010-03-15
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
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