摘要:
A Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which comprises using as a starting compound as a (phenylthio)acetic acid derivative or salts thereof represented by the general formula: wherein X1 represents a halogen atom, is useful as a safe process for mass production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which is useful as a remedy for disease of central and peripheral nerve.
摘要:
A Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which comprises using as a starting compound as a (phenylthio)acetic acid derivative or salts thereof represented by the general formula: wherein X1 represents a halogen atom, is useful as a safe process for mass production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which is useful as a remedy for disease of central and peripheral nerve.
摘要:
A Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which comprises using as a starting compound as a (phenylthio)acetic acid derivative or salts thereof represented by the general formula: wherein X1 represents a halogen atom, is useful as a safe process for mass production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which is useful as a remedy for disease of central and peripheral nerve.
摘要:
A Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which comprises using as a starting compound as a (phenylthio)acetic acid derivative or salts thereof represented by the general formula: wherein X1 represents a halogen atom, is useful as a safe process for mass production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which is useful as a remedy for disease of central and peripheral nerve.
摘要:
Compounds of Formula IA and Formula IB are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
摘要:
A liquid crystal display device includes a plurality of pixel circuits, data lines, and a data-line driving circuit connected to the data lines. Each of the pixel circuits includes a pixel capacitance having one end provided with a common potential. In accordance with a grayscale value for one of the plurality of pixel circuits, the data-line driving circuit selectively outputs a positive-polarity signal and a negative-polarity signal to the one pixel circuit. The data-line driving circuit outputs the positive-polarity signal and the negative-polarity signal so that an average of a potential of the positive-polarity signal and a potential of the negative-polarity signal corresponding to the grayscale value changes in accordance with the grayscale value, a temperature, and a position of the one pixel circuit.
摘要:
A sinter of stable quality is produced by molding a powder for powder metallurgy. This process includes successively conducting the following steps: charging a powder and a solid lubricant into a mold compact formation in which the powder charged into the mold is compacted; releasing the compact from the mold; and the powder for powder metallurgy is charged again into the mold after the release step. The temperature of the mold is set at a value in the range of from the boiling point of water to the melting point of the solid lubricant. The compact can be continuously formed without causing, e.g., a failure in the feeding of the powder for powder metallurgy. The sinter obtained by sintering the compact is almost even in strength and density.
摘要:
Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
摘要:
Compounds of Formula (IA) and Formula (IB) are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
摘要:
The present disclosure relates to compounds useful as agonists of the cannabinoid receptors. The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment of various disorders, either alone or in combination therapy. The compounds of the invention have Formula (I).