摘要:
Dermatan sulfate compositions having certain characteristics have been found to have thrombolytic activity. Dermatan sulfate combined with tissue plasminogen activator (t-PA) enhances the thrombolytic activity of t-PA. Antithrombotic compositions containing dermatan sulfates can be used for treating various thrombotic diseases.
摘要:
A keratan sulfate oligosaccharide which comprises from two to five sugar units and has sulfated N-acetylglucosamine at the reducing end and in a molecule of which at least two hydroxyl groups are sulfated, preferably, which contains at least disaccharide represented by the formula Gal(6S)-GlcNAc(6S) (in the formula, Gal, GlcN, Ac, and 6S represent a galactose, a glucosamine, an acetyl group, and a 6-O-sulfate ester, respectively) as a constitutional ingredient, and/or pharmaceutically acceptable salt thereof are used as active ingredients of anti-inflammatory agents, antiallergic agents, immunomodulators, cell differentiation inducers, and apoptosis inducers.
摘要:
A keratan sulfate oligosaccharide which comprises from two to five sugar units and has sulfated N-acetylglucosamine at the reducing end and in a molecule of which at least two hydroxyl groups are sulfated, preferably, which contains at least disaccharide represented by the formula Gal(6S)-GlcNAc(6S) (in the formula, Gal, GlcN, Ac, and 6S represent a galactose, a glucosamine, an acetyl group, and a 6-O-sulfate ester, respectively) as a constitutional ingredient, and/or pharmaceutically acceptable salt thereof are used as active ingredients of anti-inflammatory agents, antiallergic agents, immunomodulators, cell differentiation inducers, and apoptosis inducers.
摘要:
A developing device includes a developer bearer, a casing defining an upper compartment to contain the developer and a lower compartment disposed lower than the upper compartment, to contain the developer, and a first conveyor and a second conveyor disposed in the upper compartment and the lower compartment, respectively, to convey the developer in a longitudinal direction of the developer bearer and circulate the developer between the upper compartment and the lower compartment through a first communicating opening, through which the developer is conveyed upward, and a second communicating opening. A developer-lifting range of the upper compartment, which opposes the first communicating opening, is larger in volume than a developer-lifting range of the lower compartment. One of the upper compartment and the lower compartment is disposed adjacent to the developer bearer to supply the developer to the developer bearer.
摘要:
A developing device includes a developer bearer, a magnetic field generator, a casing having an opening, a developer conveyor to rotate inside a developer containing compartment below the developer bearer, and a developer regulator. A side wall of the casing defines a bottom end of the opening, and the developer regulator is disposed on the side wall. The side wall includes an upper end face facing the developer bearer below an axis of the developer bearer and a curved inner face along an orbit of rotation of the developer conveyor, extending from below the developer conveyor toward the upper end face. On a virtual plane perpendicular to the axis of the developer bearer, an intersection between a tangent line to an upper end of the curved inner face and the surface of the developer bearer is in a range from a tangential magnetic-flux peak and a closest approach point.
摘要:
A powder container includes: a powder containing unit which has an opening portion formed at one end portion thereof, contains a powder therein, and is formed of a flexible material; a discharging unit which is provided in the end portion provided with the opening portion, is fixed to a powder conveying apparatus, and discharges the powder delivered from the opening portion out to the powder conveying apparatus; and a portion to be locked which is provided in an end portion opposite to the opening portion and is locked to a locking portion of the powder conveying apparatus while a delivery member is biased in a direction opposite to the movement direction. When the delivery member is pressed inward from the outside of the powder containing unit so as to move toward the opening portion, the powder is delivered out from the opening portion.
摘要:
A powder conveying apparatus includes a powder containing unit that contains powder and at least a portion of which is deformable; a discharging unit that discharges the powder from the powder housing unit to an outside; a delivery member that moves toward the discharging unit side while pushing the deformable portion of the powder containing unit inward to thereby convey the powder to the discharging unit; and an oscillation applying unit that applies oscillation to the discharging unit. Driving of the oscillation applying unit is controlled in response to an operation of the delivery member.
摘要:
A powder container includes: a powder containing unit that contains powder and at least a part of which is deformable; a discharging unit that receives the powder supplied from an opening of the powder containing unit via an inlet arranged on the discharging unit and discharges the powder to a supply destination; an elastic member that is arranged on a periphery of the inlet of the discharging unit; and a seal member that is arranged on the powder containing unit and seals the opening. The seal member is sandwiched between the discharging unit and the powder containing unit via the elastic member such that the seal member is removable from between the discharging unit and the powder containing unit.
摘要:
A development device includes a developer bearer to carry by rotation developer to a development range facing a latent image bearer, and a developer regulator to adjust an amount of developer transported to the development range by the developer bearer. Multiple projections are formed in a surface of the developer bearer, and the developer bearer rotates in a reverse direction to a direction of rotation for image development while image development is not performed. The developer regulator includes a blade having a first end held by a regulator holder and a second end that contacts the multiple projections formed in the surface of the developer bearer and is disposed in a direction counter to the direction of rotation of the developer bearer for image development.
摘要:
A development device includes a developer carrier configured to carry developer and disposed in a development case, partly exposed from an opening of the development case facing an image carrier, a developer-transporting member configured to transport the developer to the developer carrier, and a discharging member housing a discharging space including a communicating path connecting to an area where the developer carrier faces the developer-transporting member, from which air is discharged into the discharging space, and a discharging port that opens in a longitudinal direction of the developer-transporting member, from which air is discharged from the discharging space.