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    Agent for Treatment of Eye Diseases
    1.
    发明申请
    Agent for Treatment of Eye Diseases 有权
    眼部疾病治疗药物

    公开(公告)号：US20140148416A1

    公开(公告)日：2014-05-29

    申请号：US13876596

    申请日：2011-09-30

    申请人： Akira Kakizuka ,  Seiji Hori ,  Hanako Ikeda ,  Nagahisa Yoshimura ,  Noriko Nakano ,  Toshiyuki Shudo ,  Tomohiro Fuchigami

    发明人： Akira Kakizuka ,  Seiji Hori ,  Hanako Ikeda ,  Nagahisa Yoshimura ,  Noriko Nakano ,  Toshiyuki Shudo ,  Tomohiro Fuchigami

    IPC分类号： C07D213/76

    CPC分类号： C07D213/76 ,  A61K31/4418 ,  C07D213/77

    摘要： The present invention provides agents effective to treat eye diseases, pharmaceutical compositions comprising them, methods for preparing pharmaceuticals for treatment of eye diseases comprising using the agents, use of the agents in manufacture of pharmaceuticals for treatment of eye diseases and methods for treating eye diseases comprising administering the agents or the pharmaceutical compositions. The eye diseases treated by the present invention include particularly glaucoma, especially normal tension glaucoma, or retinitis pigmentosa. The present invention provides the compound of formula (I) wherein R is as defined in the description.

    摘要翻译： 本发明提供了有效治疗眼睛疾病的药剂，包含它们的药物组合物，用于治疗眼部疾病的药物的制备方法，包括使用该药剂，制备用于治疗眼部疾病的药物的用途以及治疗眼部疾病的方法的用途，所述方法包括 给药或药物组合物。 通过本发明治疗的眼部疾病特别包括青光眼，特别是正常的紧张性青光眼或色素性视网膜炎。 本发明提供其中R如说明书中所定义的式（I）化合物。

    Agent for treatment of eye diseases
    2.
    发明授权
    Agent for treatment of eye diseases 有权
    眼病治疗药

    公开(公告)号：US09206129B2

    公开(公告)日：2015-12-08

    申请号：US13876596

    申请日：2011-09-30

    申请人： Akira Kakizuka ,  Seiji Hori ,  Hanako Ikeda ,  Nagahisa Yoshimura ,  Noriko Nakano ,  Toshiyuki Shudo ,  Tomohiro Fuchigami

    发明人： Akira Kakizuka ,  Seiji Hori ,  Hanako Ikeda ,  Nagahisa Yoshimura ,  Noriko Nakano ,  Toshiyuki Shudo ,  Tomohiro Fuchigami

    IPC分类号： C07D213/76 ,  A61K31/4418 ,  C07D213/77

    CPC分类号： C07D213/76 ,  A61K31/4418 ,  C07D213/77

    摘要： The present invention provides agents effective to treat eye diseases, pharmaceutical compositions comprising them, methods for preparing pharmaceuticals for treatment of eye diseases comprising using the agents, use of the agents in manufacture of pharmaceuticals for treatment of eye diseases and methods for treating eye diseases comprising administering the agents or the pharmaceutical compositions. The eye diseases treated by the present invention include particularly glaucoma, especially normal tension glaucoma, or retinitis pigmentosa. The present invention provides the compound of formula (I) wherein R is as defined in the description.

    摘要翻译： 本发明提供了有效治疗眼睛疾病的药剂，包含它们的药物组合物，用于治疗眼部疾病的药物的制备方法，包括使用该药剂，制备用于治疗眼部疾病的药物的用途以及治疗眼部疾病的方法的用途，所述方法包括 给药或药物组合物。 通过本发明治疗的眼部疾病特别包括青光眼，特别是正常的紧张性青光眼或色素性视网膜炎。 本发明提供其中R如说明书中所定义的式（I）化合物。

    ADHESIVE COMPOSITION AND ADHESIVE SHEET
    3.
    发明申请
    ADHESIVE COMPOSITION AND ADHESIVE SHEET 审中-公开
    胶粘组合物和粘合片

    公开(公告)号：US20140141271A1

    公开(公告)日：2014-05-22

    申请号：US14129210

    申请日：2012-06-27

    申请人： Kazue Uemura ,  Yoshitomo Ono ,  Yumiko Amino ,  Satoshi Kawada ,  Hanako Ikeda

    发明人： Kazue Uemura ,  Yoshitomo Ono ,  Yumiko Amino ,  Satoshi Kawada ,  Hanako Ikeda

    IPC分类号： C09K3/10 ,  C09J7/00

    CPC分类号： C09K3/1006 ,  C08L23/20 ,  C08L23/22 ,  C08L2203/16 ,  C08L2205/02 ,  C09J7/00 ,  C09J7/10 ,  C09J123/20 ,  C09J123/22 ,  C09J2201/622 ,  C09J2423/00 ,  H01L51/5246 ,  H01L51/5253 ,  Y10T428/31938

    摘要： Provided is an adhesive sheet having an adhesive layer formed of an adhesive composition that contains 100 parts by mass of a polyisobutylene-based resin (A) having a weight-average molecular weight of from 270,000 to 480,000, from 5 to 55 parts by mass of a polyisobutylene-based resin (B) having a weight-average molecular weight of from 100,000 to 250,000, and from 10 to 55 parts by mass of a hydrogenated petroleum resin (C) having a softening point of from 90 to 135° C.; and provided is an adhesive sheet having at least one adhesive layer wherein the probe tack of the adhesive layer, as measured at a peel rate of 600 mm/min according to JIS-Z0237 (1991), has two maximum values and wherein the first maximum value P1 detected first is at least 4.0 N and the ratio of the second maximum value P2 detected secondarily to the first maximum value P1 [P2/P1] is from 0.25 to 1.50. The adhesive sheets have excellent adhesion force and retention force, can prevent occurrence of zipping, have a low moisture vapor transmission rate, are excellent in transparency and can retard outgas generation.

    摘要翻译： 提供一种粘合剂层，其具有由粘合剂组合物形成的粘合剂层，所述粘合剂组合物含有100质量份的重均分子量为27万至48万的聚异丁烯类树脂（A），5至55质量份的 重均分子量为100,000〜250,000的聚异丁烯类树脂（B）和软化点为90〜135℃的氢化石油树脂（C）10〜55质量份。 并且提供了具有至少一个粘合剂层的粘合片，其中根据JIS-Z0237（1991）以600mm / min的剥离速度测量的粘合剂层的探针粘性具有两个最大值，并且其中第一最大值 首先检测到的值P1至少为4.0N，二次检测的第二最大值P2与第一最大值P1 [P2 / P1]的比值为0.25〜1.50。 粘合片具有优异的粘附力和保持力，可以防止拉伸发生，具有低的蒸汽透过率，透明性优异并且可以延缓产生气体。