公开(公告)号：US20090176835A1

公开(公告)日：2009-07-09

申请号：US12398422

申请日：2009-03-05

申请人： Yoshiro KITAHARA ,  Tomohisa OKUTSU ,  Akira MITSUI ,  Akira OKANO

发明人： Yoshiro KITAHARA ,  Tomohisa OKUTSU ,  Akira MITSUI ,  Akira OKANO

IPC分类号： A61K31/197 ,  A61P3/00 ,  A61K31/445

CPC分类号： A61K31/426 ,  A61K31/00 ,  A61K31/175 ,  A61K31/198

摘要： The present invention provides a pharmaceutical composition for suppression of the expression of ATP citrate lyase, which contains a compound that suppresses the expression of ATP citrate lyase by the in vivo administration. The compounds suppress the expression of ATP citrate lyase by the in vivo administration include insulin secretagogues such as nateglinide. This pharmaceutical composition is effective in preventing, improving and treating metabolic syndrome, in particular, liver disorders related to abnormal lipid metabolism such as fatty liver and NASH.

摘要翻译： 本发明提供抑制ATP柠檬酸裂合酶表达的药物组合物，其含有通过体内给药抑制ATP柠檬酸裂解酶的表达的化合物。 该化合物通过体内施用抑制ATP柠檬酸裂解酶的表达，包括胰岛素促分泌素如那格列奈。 该药物组合物可有效预防，改善和治疗代谢综合征，特别是与脂肪肝和NASH等脂代谢异常相关的肝脏疾病。

公开(公告)号：US20090253116A1

公开(公告)日：2009-10-08

申请号：US12365269

申请日：2009-02-04

申请人： Mitsuo TAKAHASHI ,  Nobukazu ONO ,  Toshihiko ANDO ,  Akira OKANO ,  Minoru YAMAKADO

发明人： Mitsuo TAKAHASHI ,  Nobukazu ONO ,  Toshihiko ANDO ,  Akira OKANO ,  Minoru YAMAKADO

IPC分类号： C12Q1/00 ,  C12M1/34

CPC分类号： G01N33/6812 ,  G01N2800/60

摘要： According to the method of evaluating metabolic syndrome, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and the state of metabolic syndrome in the subject is evaluated based on the measured amino acid concentration data of the subject.

摘要翻译： 根据评价代谢综合征的方法，测定从待评价对象收集的血液中氨基酸浓度的氨基酸浓度数据，并根据测定的氨基酸浓度来评价受试者的代谢综合征状态 主题的数据。

公开(公告)号：US20120325068A1

公开(公告)日：2012-12-27

申请号：US13528054

申请日：2012-06-20

申请人： Sadaji SUTOU ,  Futoshi MATSUE ,  Akira OKANO

发明人： Sadaji SUTOU ,  Futoshi MATSUE ,  Akira OKANO

IPC分类号： B26D1/18

CPC分类号： B26D3/16 ,  B26D1/18 ,  B26D7/2621 ,  Y10T83/7693

摘要： To restrain shifting of a circular blade, and reduce a cutting-in angle of the circular blade with respect to the tape roll main body, both ends of a rotatable blade shaft 38 is supported by a pair of shaft bearings 39a and 39b of shaft supporting members 37 of a tool post 20. The circular blade 21 is mounted to the blade shaft 38, between the shaft bearings 39a and 39b. This prevents the blade shaft 38 from being shifted or bent, restrains shifting of the circular blade 21, and reduce the cutting-in angle of the circular blade 21 with respect to the tape roll main body.

摘要翻译： 为了抑制圆形刀片的​​移动，并且相对于带卷辊主体减小圆形刀片的​​切入角度，可旋转刀片轴38的两端由轴支撑的一对轴承39a和39b支撑 工具柱20的构件37.圆形叶片21安装到叶片轴38上，在轴承轴承39a和39b之间。 这防止了叶片轴38被移动或弯曲，从而限制了圆形刀片21的移动，并且减小了圆形刀片21相对于带卷主体的切入角度。

公开(公告)号：US20090250842A1

公开(公告)日：2009-10-08

申请号：US12483350

申请日：2009-06-12

申请人： Akira OKANO

发明人： Akira OKANO

IPC分类号： C08J5/10

CPC分类号： G03G15/161 ,  C08K3/04 ,  C08K3/08 ,  G03G15/162 ,  G03G2215/1623 ,  C08L71/00

摘要： The present invention provides an intermediate transfer belt of a single layer made from a resin composition containing a crystalline thermoplastic resin and 5 parts by mass or more and 40 parts by mass or less of an conductive filler with respect to 100 parts by mass of the crystalline thermoplastic resin, wherein the surface hardness of the intermediate transfer belt is 0.25 GPa or higher and 0.60 GPa or lower when measured using a nanoindentation method; and an electrophotographic apparatus having the intermediate transfer belt.

摘要翻译： 本发明提供一种由含有结晶热塑性树脂的树脂组合物和5质量份以上40质量份以下的导电性填料构成的单层中间转印带，相对于100质量份的结晶 热塑性树脂，其中当使用纳米压痕法测量时，中间转印带的表面硬度为0.25GPa以上且0.60GPa以下; 以及具有中间转印带的电子照相设备。