公开(公告)号：US07121270B1

公开(公告)日：2006-10-17

申请号：US11212580

申请日：2005-08-29

Applicant: Alexander Plotnikov

Inventor： Alexander Plotnikov

IPC: F02P3/04 ,  F02P3/08

CPC classification number: F02P3/0846 ,  F02P3/0853 ,  F02P15/08 ,  F02P15/10 ,  F02P15/12

Abstract: An ignition system providing power and duration controlled ignition spark, comprises a spark controller, first switching energy accumulator, storage capacitor, and second switching energy accumulator with an ignition coil. The ignition system utilizes dual means of switching energy accumulation, internal energy transfer, and three means of energy release to the ignition spark, working in all possible combinations managed by means of the spark controller depending on engine operating conditions, and provides continuous bipolar ignition spark. Spark profile is regulated by means of control signals (2) and (3) based on their frequency, duty cycle, interrelation, and running time.

Abstract translation: 提供动力和持续时间控制的点火火花的点火系统包括火花控制器，第一开关蓄能器，储能电容器和具有点火线圈的第二开关蓄能器。 点火系统采用双重方式切换能量积聚，内部能量转移和三种能量释放装置的点火火花，根据发动机工作条件，通过火花控制器管理的所有可能组合工作，并提供连续的双极点火火花 。 基于它们的频率，占空比，相关性和运行时间，通过控制信号（2）和（3）来调节火花轮廓。

公开(公告)号：US20140066410A1

公开(公告)日：2014-03-06

申请号：US14001074

申请日：2012-02-23

Applicant: Ming-Ming Zhou ,  Michael Ohlmeyer ,  Shiraz Mujtaba ,  Alexander Plotnikov ,  David Kastrinsky ,  Guangtao Zhang

Inventor： Ming-Ming Zhou ,  Michael Ohlmeyer ,  Shiraz Mujtaba ,  Alexander Plotnikov ,  David Kastrinsky ,  Guangtao Zhang

IPC: C07D213/76 ,  C07C311/44

CPC classification number: C07D213/76 ,  A61K31/18 ,  A61K45/06 ,  C07C311/44 ,  A61K2300/00

Abstract: This disclosure relates generally to compounds and compositions comprising one or more diphenylethylene, diphenylethylyne, and azobenzene analogs. These compounds are useful for treating diseases associated with NF-kB and p53 activity, such as cancer and inflammatory disease.

Abstract translation: 本公开一般涉及包含一种或多种二苯基乙烯，二苯基乙烯基和偶氮苯类似物的化合物和组合物。 这些化合物可用于治疗与NF-kB和p53活性相关的疾病，如癌症和炎性疾病。

公开(公告)号：US07129072B1

公开(公告)日：2006-10-31

申请号：US10049429

申请日：2000-08-30

Applicant: Joseph Schlessinger ,  Stevan R. Hubbard ,  Moosa Mohammadi ,  Alexander Plotnikov ,  Zhongtao Zhang ,  Xiang-Peng Kong

Inventor： Joseph Schlessinger ,  Stevan R. Hubbard ,  Moosa Mohammadi ,  Alexander Plotnikov ,  Zhongtao Zhang ,  Xiang-Peng Kong

IPC: C12N9/12

CPC classification number: C07K14/71 ,  C07K14/50 ,  C07K2299/00

Abstract: The determination and use of three dimensional structures of receptor protein tyrosine kinases and/or their ligands are described. One particular group of such structures includes three dimensional structures of the extracellular domain of RPTKs. The three dimensional structures of RPTKs can faciliate the design and identification of modulators of RPTK function. Other such structures can include of RPTK ligands, such as stem cell factor or a fragment thereof. Modulators of RPTK function can be used to treat diseases that are mediated by inappropriate RPTK activity.

Abstract translation: 描述了受体蛋白酪氨酸激酶和/或其配体的三维结构的确定和使用。 这种结构的一个特定组包括RPTK的细胞外结构域的三维结构。 RPTK的三维结构可以促进RPTK功能调制器的设计和鉴定。 其他这样的结构可以包括RPTK配体，例如干细胞因子或其片段。 RPTK功能的调节剂可用于治疗由不适当RPTK活动介导的疾病。