摘要:
There are provided inter alia derivatives of a benzenoid ansamycin which contain a 1,4-dihydroxyphenyl moiety bearing at position 6 an amino carboxy substituent, in which position 2 and the carboxy substituent at position 6 are connected by an aliphatic chain of varying length characterised in that one or both of the 1-hydroxy and the 4-hydroxy position(s) of the phenyl ring are independently derivatised by an aminoalkyleneaminocarbonyl group, which alkylene group, which may optionally be substituted by alkyl groups, has a chain length of 2 or 3 carbons and which derivatising group(s) increase the water solubility and/or the bioavailability of the parent molecule but which are capable of being removed in-vivo. Such compounds are described for the treatment of cancer or B-cell malignancies.
摘要:
A DC power generating system includes a permanent magnet generator (PMG), an active rectifier in electrical communication with the PMG, and a controller in electrical communication with the active rectifier, wherein the controller is configured to regulate d-q components of a stator current of the PMG in a synchronous reference frame.
摘要:
A power management and distribution (PMAD) system includes a main DC bus, an auxiliary DC bus, a power converter, one or more hybrid solid-state circuit breakers, and a controller. The power converter converts power from the main DC bus to provide a regulated output to the auxiliary bus. Each hybrid SSCB includes a main switch connected between the main DC bus and a load and an auxiliary switch connected between the auxiliary DC bus and the load. The controller selectively turns the main switch and the auxiliary switch On/Off to selectively supply power from the main DC bus and/or the auxiliary DC bus to the load, and to selectively regulate the voltage on the auxiliary DC bus.
摘要:
An electric power system includes multiple components that include a generator, a rectifier and a power management and distribution center. Multiple sensors are configured to provide actual responses relating to each of the components. Multiple simulation models are configured to simulate responses of each of the components, and multiple comparators are configured to compare the actual responses to the simulated responses and provide compared values. A diagnostic module is in communication with the comparators and is configured to determine at least one fault in each of the components.
摘要:
A power generation system includes a prime mover, a generator mechanically connected to the prime mover, the generator including a field winding portion and an armature winding portion, a direct current bus node, a first variable frequency drive having an input electrically connected to the bus node and an output electrically connected to the armature winding portion, and an inverter having an input electrically connected to the bus node and an output electrically connected to the field winding portion.
摘要:
A system for controlling a solid state circuit breaker comprises a solid state power switch, and a controller for providing a gate voltage to the power switch. During turnoff of the solid state power switch, the controller reduces the gate voltage to an intermediate level for a specified time period and then reduces the gate voltage to a turnoff level.
摘要:
A method of startup of an electric start electrical power generating system (EPGS) is provided. The EPGS includes a generator configured to power a direct current (DC) load via a DC bus. The method includes: disconnecting the DC load from the DC bus; connecting a battery to a boost converter, the boost converter being connected to the generator; powering the generator using the battery via the boost converter; when the generator reaches a minimum speed: disconnecting the battery from the boost converter; deactivating the boost converter; and activating a synchronous active filter, the synchronous active filter being connected to the DC bus; bringing up a voltage on the DC bus by the generator; and when the voltage on the DC bus reaches a predetermined level, connecting the DC load to the DC bus.
摘要:
A DC power generating system includes a permanent magnet generator (PMG), an active rectifier in electrical communication with the PMG, and a controller in electrical communication with the active rectifier, wherein the controller is configured to regulate d-q components of a stator current of the PMG in a synchronous reference frame.
摘要:
A power management and distribution (PMAD) system includes a main DC bus, an auxiliary DC bus, a power converter, one or more hybrid solid-state circuit breakers, and a controller. The power converter converts power from the main DC bus to provide a regulated output to the auxiliary bus. Each hybrid SSCB includes a main switch connected between the main DC bus and a load and an auxiliary switch connected between the auxiliary DC bus and the load. The controller selectively turns the main switch and the auxiliary switch On/Off to selectively supply power from the main DC bus and/or the auxiliary DC bus to the load, and to selectively regulate the voltage on the auxiliary DC bus.
摘要:
An active damping switching system can include an active damper apparatus having a stabilization resistor, a stabilization switch coupled to the stabilization resistor, an active damper controller coupled to the stabilization switch, a current sensor coupled to the active damper controller. The system can further include a direct current power source coupled to the active damper apparatus, a constant power load and an input filter disposed between the constant power load and the active damper apparatus.