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公开(公告)号：US20060206192A1
公开(公告)日：2006-09-14
申请号：US11432838
申请日：2006-05-12
申请人： Allen Tower , Philipp Bonhoeffer , Michael Martin
发明人： Allen Tower , Philipp Bonhoeffer , Michael Martin
IPC分类号： A61F2/06
CPC分类号： A61F2/2433 , A61F2/2412 , A61F2/2475 , A61F2/90 , A61F2/958
摘要： A system for percutaneously inserting a prosthesis containing a biological replacement for a defective valve into an implantation site through a body lumen. The system contains a balloon catheter upon which a collapsable stent containing a venous valvular replacement is mounted. A protective shield is slidably mounted upon the catheter that is movable between a closed position over the balloon and an open position wherein the balloon can be inflated to expand the stent. A central lumen runs through the catheter that is formed of stainless steel. The central lumen provides a one to one torque ratio between the proximal end of the catheter and the distal end to enhance the steerability of the catheter. The vein of the replacement is reduced in thickness between 50% and 90% of its original size thereby considerably reducing the size of the replacement package when the stem is collapsed upon the balloon of the catheter.
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公开(公告)号：US08858619B2
公开(公告)日：2014-10-14
申请号：US11432838
申请日：2006-05-12
CPC分类号： A61F2/2433 , A61F2/2412 , A61F2/2475 , A61F2/90 , A61F2/958
摘要： A system for percutaneously inserting a prosthesis containing a biological replacement for a defective valve into an implantation site through a body lumen. The system contains a balloon catheter upon which a collapsable stent containing a venous valvular replacement is mounted. A protective shield is slidably mounted upon the catheter that is movable between a closed position over the balloon and an open position wherein the balloon can be inflated to expand the stent. A central lumen runs through the catheter that is formed of stainless steel. The central lumen provides a one to one torque ratio between the proximal end of the catheter and the distal end to enhance the steerability of the catheter. The vein of the replacement is reduced in thickness between 50% and 90% of its original size thereby considerably reducing the size of the replacement package when the stem is collapsed upon the balloon of the catheter.
摘要翻译： 一种用于将含有有缺陷的瓣膜的生物学替代物的假体经由体腔插入植入部位的系统。 该系统包含气囊导管，在其上安装含有静脉瓣膜置换物的可收缩支架。 保护罩可滑动地安装在导管上，该导管可在气囊上的关闭位置和打开位置之间移动，其中气囊可膨胀以使支架膨胀。 中央管腔穿过由不锈钢形成的导管。 中心腔在导管的近端和远端之间提供一到一个扭矩比，以增强导管的可操纵性。 更换的静脉厚度在其原始尺寸的50％至90％之间减小，从而当杆在导管的气囊上塌陷时大大减小了更换包装的尺寸。
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公开(公告)号：US20080243246A1
公开(公告)日：2008-10-02
申请号：US12070387
申请日：2008-02-15
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2409 , A61F2/2433 , A61F2/2436 , A61F2/958 , A61F2210/0014 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , A61F2230/0069 , A61F2310/00023
摘要： A replacement prosthetic heart valve for engagement with a structure of a previously implanted prosthetic heart valve. The replacement heart valve includes a stent structure including a generally tubular body portion with an interior area and a series of wire portions arranged in a mesh-like configuration, and at least one stent post engaging structure extending radially outwardly from the body portion for engaging with an outer surface of a stent post of the previously implanted prosthetic heart valve. The stent structure further includes at least two leaflets attached within the interior area of the tubular body portion of the stent structure.
摘要翻译： 替换假体心脏瓣膜，用于与先前植入的假体心脏瓣膜的结构接合。 替换心脏瓣膜包括支架结构，该支架结构包括具有内部区域和布置成网状构造的一系列丝线部分的大致管状主体部分和至少一个从主体部分径向向外延伸以用于与 先前植入的假体心脏瓣膜的支架柱的外表面。 支架结构还包括附接在支架结构的管状主体部分的内部区域内的至少两个小叶。
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公开(公告)号：US20080015671A1
公开(公告)日：2008-01-17
申请号：US11791193
申请日：2005-11-21
申请人： Philipp Bonhoeffer
发明人： Philipp Bonhoeffer
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2/2475 , A61F2230/0078
摘要： Provided is a method and apparatus for placing a valve (14) in a tubular organ having a greater diameter than the valve, comprising: an expandable tubular adapter (10) having an outer portion with a diameter suitable for contacting the inner walls of the tubular organ, and an inner portion with a diameter suitable for placement of the valve; a valve mounted within the inner portion of the adapter; and a system for placing a valved vascular segment in a tubular organ having a greater inner diameter than the outer diameter of the vascular segment, comprising: an expandable tubular adapter having an outer portion with a diameter suitable for contacting the inner walls of the tubular organ, and an inner portion with a diameter suitable for placement of the valve; an expandable valved vascular segment, expandable to the diameter of the inner portion of the adapter.
摘要翻译： 提供了一种用于将阀（14）放置在具有比阀更大直径的管状器官中的方法和装置，包括：可膨胀管状适配器（10），其具有适于接触管状内壁的直径的外部部分 器官和具有适于放置阀的直径的内部部分; 安装在适配器的内部内的阀; 以及用于将有管状的血管段置于具有比血管段的外径更大的内径的管状器官中的系统，包括：具有适于接触管状器官的内壁的直径的外部部分的可扩张管状适配器 以及具有适于放置阀的直径的内部部分; 可膨胀的血管段，可扩张至适配器内部的直径。
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公开(公告)号：US08721713B2
公开(公告)日：2014-05-13
申请号：US10127969
申请日：2002-04-23
IPC分类号： A61M25/01
CPC分类号： A61F2/2433 , A61F2/2412 , A61F2/2475 , A61F2/90 , A61F2/958
摘要： A system for percutaneously inserting a prosthesis containing a biological replacement for a defective valve into an implantation site through a body lumen. The system contains a balloon catheter upon which a collapsable stent containing a venous valvular replacement is mounted. A protective shield is slidably mounted upon the catheter that is movable between a closed position over the balloon and an open position wherein the balloon can be inflated to expand the stent. A central lumen runs through the catheter that is formed of stainless steel. The central lumen provides a one to one torque ratio between the proximal end of the catheter and the distal end to enhance the steerability of the catheter. The vein of the replacement is reduced in thickness between 50% and 90% of its original size thereby considerably reducing the size of the replacement package when the stem is collapsed upon the balloon of the catheter.
摘要翻译： 一种用于将含有有缺陷的瓣膜的生物学替代物的假体经由体腔插入植入部位的系统。 该系统包含气囊导管，在其上安装含有静脉瓣膜置换物的可收缩支架。 保护罩可滑动地安装在导管上，该导管可在气囊上的关闭位置和打开位置之间移动，其中气囊可膨胀以使支架膨胀。 中央管腔穿过由不锈钢形成的导管。 中心腔在导管的近端和远端之间提供一到一个扭矩比，以增强导管的可操纵性。 更换的静脉厚度在其原始尺寸的50％至90％之间减小，从而当杆在导管的气囊上塌陷时大大减小了更换包装的尺寸。
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公开(公告)号：US08585756B2
公开(公告)日：2013-11-19
申请号：US13279800
申请日：2011-10-24
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2002/061 , A61F2230/0054 , A61F2250/001
摘要： The implant implantation unit (2), at a determined position in the tubular element (51) with a wall comprising a cavity (50), is pushed there by a catheter (60) and the unit comprises deformable feelers (31) to, under the control of remote activation elements (42), change from a stowed form to a deployed functional form, to detect the cavity (50) and position itself there with reference to the position of the cavity.
摘要翻译： 在具有包括空腔（50）的壁的管状元件（51）中的确定位置处的植入物植入单元（2）通过导管（60）被推入，并且该单元包括可变形的触针（31） 远程激活元件（42）的控制从收起的形式改变为展开的功能形式，以参考空腔的位置来检测空腔（50）并将其自身定位在那里。
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公开(公告)号：US08206437B2
公开(公告)日：2012-06-26
申请号：US12407342
申请日：2009-03-19
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2002/061 , A61F2230/0054 , A61F2250/001
摘要： The implant implantation unit (2), at a determined position in the tubular element (51) with a wall comprising a cavity (50), is pushed there by a catheter (60) and the unit comprises deformable feelers (31) to, under the control of remote activation elements (42), change from a stowed form to a deployed functional form, to detect the cavity (50) and position itself there with reference to the position of the cavity.
摘要翻译： 在具有包括空腔（50）的壁的管状元件（51）中的确定位置处的植入物植入单元（2）通过导管（60）被推入，并且该单元包括可变形的触针（31） 远程激活元件（42）的控制从收起的形式改变为展开的功能形式，以参考空腔的位置来检测空腔（50）并将其自身定位在那里。
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公开(公告)号：US20090192601A1
公开(公告)日：2009-07-30
申请号：US12358388
申请日：2009-01-23
申请人： Nasser Rafiee , Morgan House , Nareak Douk , Philipp Bonhoeffer
发明人： Nasser Rafiee , Morgan House , Nareak Douk , Philipp Bonhoeffer
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2/2436 , A61F2002/9522 , A61F2250/0039 , A61M5/007 , A61M25/0043 , A61M2025/0057
摘要： Described is a delivery system for minimally invasive delivery of a self-expandable stent to a body lumen, and particularly delivery of a prosthetic valve to the right ventricular outflow tract. Also described is a method of loading a stent onto such a delivery system, and a method of delivering a self-expandable stent to a desired anatomic site.
摘要翻译： 描述了用于将自扩张支架微创递送到体腔的输送系统，特别是将人工瓣膜输送到右心室流出道。 还描述了将支架装载到这种递送系统上的方法，以及将自扩张支架递送到期望的解剖部位的方法。
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公开(公告)号：US08801776B2
公开(公告)日：2014-08-12
申请号：US12391330
申请日：2009-02-24
申请人： Morgan House , Philipp Bonhoeffer , Nasser Rafiee , Rany Huynh Busold , Nareak Douk , Juan-Pablo Mas , Stuart MacDonald , Michael Finney
发明人： Morgan House , Philipp Bonhoeffer , Nasser Rafiee , Rany Huynh Busold , Nareak Douk , Juan-Pablo Mas , Stuart MacDonald , Michael Finney
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/0023 , A61F2250/0039 , A61F2250/0048
摘要： Described is a prosthetic valve assembly comprising: a radially self-expandable stent configured to expand to bear against a wall of a native body lumen; and an implantable prosthetic valve, having a diameter, the valve being mounted inside the stent; wherein the diameter of the stent is greater than the diameter of the prosthetic valve.
摘要翻译： 描述了一种假体瓣膜组件，其包括：径向自扩张支架，其构造成膨胀以抵靠本体体腔的壁; 以及具有直径的植入式假体瓣膜，所述瓣膜安装在所述支架内; 其中支架的直径大于人工瓣膜的直径。
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公开(公告)号：US08613765B2
公开(公告)日：2013-12-24
申请号：US13178112
申请日：2011-07-07
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2220/0075 , A61F2230/0078 , A61F2250/001 , A61F2250/0039 , A61F2250/0071 , A61F2250/0082
摘要： A heart valve that can be expanded following its implantation in a patient, such as to accommodate the growth of a patient and the corresponding growth of the area where the valve is implanted, and to minimize paravalvular leakage. In one aspect, the invention may maximize the orifice size of the surgical valve. The invention includes expandable implantable conduits and expandable bioprosthetic stented valves. In one aspect of the invention, the valve may be adapted to accommodate growth of a patient to address limitation on bioprosthetic valve lifespans.
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