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公开(公告)号：US08615297B2
公开(公告)日：2013-12-24
申请号：US13595688
申请日：2012-08-27
IPC分类号： A61N1/08
CPC分类号： A61N1/3686 , A61N1/056 , A61N1/08 , A61N1/36514 , A61N1/3702 , A61N1/3704 , A61N1/371 , A61N1/37223 , A61N1/37247 , A61N2001/083
摘要： Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.
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公开(公告)号：US08265736B2
公开(公告)日：2012-09-11
申请号：US11890668
申请日：2007-08-07
IPC分类号： A61B5/04
CPC分类号： A61N1/3686 , A61N1/056 , A61N1/08 , A61N1/36514 , A61N1/3702 , A61N1/3704 , A61N1/371 , A61N1/37223 , A61N1/37247 , A61N2001/083
摘要： Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.
摘要翻译： 描述了选择多电极起搏装置的电极组合的方法。 针对多个电极组合中的每一个评估支持与规定治疗一致的心脏功能的电极组合参数。 针对多个电极组合中的每一个评估不支持心脏功能的电极组合参数。 基于参数评估确定电极组合的顺序。 基于顺序选择电极组合，并且使用所选择的电极组合递送治疗。
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公开(公告)号：US20090043351A1
公开(公告)日：2009-02-12
申请号：US11890668
申请日：2007-08-07
IPC分类号： A61N1/08
CPC分类号： A61N1/3686 , A61N1/056 , A61N1/08 , A61N1/36514 , A61N1/3702 , A61N1/3704 , A61N1/371 , A61N1/37223 , A61N1/37247 , A61N2001/083
摘要： Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.
摘要翻译： 描述了选择多电极起搏装置的电极组合的方法。 针对多个电极组合中的每一个评估支持与规定治疗一致的心脏功能的电极组合参数。 针对多个电极组合中的每一个评估不支持心脏功能的电极组合参数。 基于参数评估确定电极组合的顺序。 基于顺序选择电极组合，并且使用所选择的电极组合递送治疗。
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公开(公告)号：US20120323291A1
公开(公告)日：2012-12-20
申请号：US13595688
申请日：2012-08-27
IPC分类号： A61N1/37
CPC分类号： A61N1/3686 , A61N1/056 , A61N1/08 , A61N1/36514 , A61N1/3702 , A61N1/3704 , A61N1/371 , A61N1/37223 , A61N1/37247 , A61N2001/083
摘要： Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.
摘要翻译： 描述了选择多电极起搏装置的电极组合的方法。 针对多个电极组合中的每一个评估支持与规定治疗一致的心脏功能的电极组合参数。 针对多个电极组合中的每一个评估不支持心脏功能的电极组合参数。 基于参数评估确定电极组合的顺序。 基于顺序选择电极组合，并且使用所选择的电极组合递送治疗。
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公开(公告)号：US08442635B2
公开(公告)日：2013-05-14
申请号：US13031762
申请日：2011-02-22
IPC分类号： A61N1/08
CPC分类号： A61N1/37282 , A61N1/368 , A61N1/3684 , A61N1/3706 , A61N2001/083
摘要： This document discusses, among other things, systems and methods for automatic electrode integrity management. Interelectrode impedance is measured for various electrode combinations of an implantable cardiac function management device. The impedance data is processed, such as at an external remote server, to determine whether an electrode is failing or has failed, to select an alternate electrode configuration, to alert a physician or patient, to predict a time-to-failure such as by using population data, or to reprogram electrode configuration or other device parameters of the implantable cardiac function management device.
摘要翻译： 本文件还讨论了自动电极完整性管理的系统和方法。 测量可植入心脏功能管理装置的各种电极组合的电极内阻抗。 处理阻抗数据，例如在外部远程服务器处，以确定电极是否发生故障或失败，选择备用电极配置，以警告医师或患者预测失效时间，例如通过 使用种群数据，或重新编程可植入心脏功能管理装置的电极配置或其他装置参数。
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公开(公告)号：US20110106199A1
公开(公告)日：2011-05-05
申请号：US12986762
申请日：2011-01-07
申请人： Aaron McCabe , Imad Libbus , Yi Zhang , Paul A. Haefner , Alok S. Sathaye , Anthony V. Caparso , M. Jason Brooke
发明人： Aaron McCabe , Imad Libbus , Yi Zhang , Paul A. Haefner , Alok S. Sathaye , Anthony V. Caparso , M. Jason Brooke
IPC分类号： A61N1/365
CPC分类号： A61N1/36139 , A61N1/36114 , A61N1/36135 , A61N1/365 , A61N1/36592 , A61N1/3962 , A61N1/3987
摘要： Various aspects of the present subject matter relate to a method. According to various method embodiments, cardiac activity is detected, and neural stimulation is synchronized with a reference event in the detected cardiac activity. Neural stimulation is titrated based on a detected response to the neural stimulation. Other aspects and embodiments are provided herein.
摘要翻译： 本主题的各个方面涉及一种方法。 根据各种方法实施例，检测心脏活动，并且神经刺激与检测到的心脏活动中的参考事件同步。 基于对神经刺激的检测反应来滴定神经刺激。 本文提供了其它方面和实施例。
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7.发明申请Capture detection based on propagated depolarization from a remote pacing site 有权基于来自远程起搏站点的传播去极化的捕获检测公开(公告)号：US20080065166A1
公开(公告)日：2008-03-13
申请号：US11517699
申请日：2006-09-08
申请人： Alok S. Sathaye , M. Jason Brooke , Scott A. Meyer
发明人： Alok S. Sathaye , M. Jason Brooke , Scott A. Meyer
IPC分类号： A61N1/00
CPC分类号： A61N1/371
摘要： A methods and devices for capture detection are based on sensing a propagated depolarization from a contralateral cardiac chamber. An intersite sensing interval is determined based on an intersite pacing delay and an intersite conduction delay associated with first and second pacing sites. Pacing pulses are delivered to the first pacing site and the second pacing site, the pacing pulses separated in time by the intersite pacing delay. An intersite sensing interval is timed. The process includes sensing, during the intersite sensing interval, at the first pacing site for a depolarization propagated to the first pacing site from the second pacing site. It a depolarization propagated from the second pacing site is not sensed, then capture of the first and second pacing sites is detected.
摘要翻译： 用于捕获检测的方法和装置基于感测来自对侧心室的传播的去极化。 基于场间起搏延迟和与第一和第二起搏部位相关联的间歇间传导延迟确定位置间感测间隔。 起搏脉冲被传送到第一起搏部位和第二起搏部位，起搏脉冲及时地通过位置间起搏延迟分开。 站间感知间隔是定时的。 该过程包括在第一起搏部位期间在站间感测间隔期间感测到从第二起搏部位传播到第一起搏部位的去极化。 从第二起搏部位传播的去极化不被感测，然后检测到第一和第二起搏部位的捕获。
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公开(公告)号：US08209013B2
公开(公告)日：2012-06-26
申请号：US11520879
申请日：2006-09-14
申请人： M. Jason Brooke , Alok S. Sathaye , Yanting Dong , Scott Walczak
发明人： M. Jason Brooke , Alok S. Sathaye , Yanting Dong , Scott Walczak
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/3712
摘要： Energy parameters for electrical stimulation pulses that produce a desired activation, and avoid an undesirable activation, are determined. A strength-duration relationship for at least one desired activation produced by therapeutic electrical stimulation is measured. A strength-duration relationship for at least one undesirable activation produced by the therapeutic electrical stimulation is provided. A medical device selects, based on the desired and undesirable strength-duration relationships, one or more energy parameters for the therapeutic electrical stimulation that produce the desired activation and avoid the undesirable activation.
摘要翻译： 确定产生所需激活的电刺激脉冲的能量参数，并避免不期望的激活。 测量通过治疗性电刺激产生的至少一种所需活化的强度 - 持续时间关系。 提供了由治疗性电刺激产生的至少一种不期望的激活的强度 - 持续时间关系。 医疗设备基于期望的和不期望的强度 - 持续时间关系选择产生所需激活的治疗性电刺激的一个或多个能量参数，并避免不期望的激活。
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公开(公告)号：US09031650B2
公开(公告)日：2015-05-12
申请号：US12986762
申请日：2011-01-07
申请人： Aaron R. McCabe , Imad Libbus , Yi Zhang , Paul A. Haefner , Alok S. Sathaye , Anthony V. Caparso , M. Jason Brooke
发明人： Aaron R. McCabe , Imad Libbus , Yi Zhang , Paul A. Haefner , Alok S. Sathaye , Anthony V. Caparso , M. Jason Brooke
CPC分类号： A61N1/36139 , A61N1/36114 , A61N1/36135 , A61N1/365 , A61N1/36592 , A61N1/3962 , A61N1/3987
摘要： Various aspects of the present subject matter relate to a method. According to various method embodiments, cardiac activity is detected, and neural stimulation is synchronized with a reference event in the detected cardiac activity. Neural stimulation is titrated based on a detected response to the neural stimulation. Other aspects and embodiments are provided herein.
摘要翻译： 本主题的各个方面涉及一种方法。 根据各种方法实施例，检测心脏活动，并且神经刺激与检测到的心脏活动中的参考事件同步。 基于对神经刺激的检测反应来滴定神经刺激。 本文提供了其它方面和实施例。
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10.发明申请公开(公告)号：US20110224751A1
公开(公告)日：2011-09-15
申请号：US13104437
申请日：2011-05-10
申请人： Alok S. Sathaye , M. Jason Brooke , Scott A. Meyer
发明人： Alok S. Sathaye , M. Jason Brooke , Scott A. Meyer
IPC分类号： A61N1/362
CPC分类号： A61N1/371
摘要： A methods and devices for capture detection are based on sensing a propagated depolarization from a contralateral cardiac chamber. An intersite sensing interval is determined based on an intersite pacing delay and an intersite conduction delay associated with first and second pacing sites. Pacing pulses are delivered to the first pacing site and the second pacing site, the pacing pulses separated in time by the intersite pacing delay. An intersite sensing interval is timed. The process includes sensing, during the intersite sensing interval, at the first pacing site for a depolarization propagated to the first pacing site from the second pacing site. It a depolarization propagated from the second pacing site is not sensed, then capture of the first and second pacing sites is detected.
摘要翻译： 用于捕获检测的方法和装置基于感测来自对侧心室的传播的去极化。 基于场间起搏延迟和与第一和第二起搏部位相关联的间歇间传导延迟确定位置间感测间隔。 起搏脉冲被传送到第一起搏部位和第二起搏部位，起搏脉冲及时地通过位置间起搏延迟分开。 站间感知间隔是定时的。 该过程包括在第一起搏部位期间在站间感测间隔期间感测到从第二起搏部位传播到第一起搏部位的去极化。 从第二起搏部位传播的去极化不被感测，然后检测到第一和第二起搏部位的捕获。
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