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公开(公告)号:US20090285766A1
公开(公告)日:2009-11-19
申请号:US11922044
申请日:2006-06-13
IPC分类号: A61K31/5415 , A61K31/045 , A61K31/403 , A61P31/00 , A61N5/06
CPC分类号: A61L2/0011 , A61K6/0035 , A61K6/0041 , A61K8/34 , A61K8/345 , A61K31/045 , A61K41/0057 , A61K41/0071 , A61K2800/434 , A61Q11/00 , A61K6/0038 , C08L71/02 , C08L77/04
摘要: The present invention provides a photosensitising composition comprising a mixture of: at least one surfactant; at least one alcohol; and/or water, with the proviso that when the at least one surfactant is an alcohol, it is different from the at least one alcohol. In particular, the composition may comprise a mixture of glycerol, ethanol and water. Alternatively, the composition may comprise a mixture of polyethylene glycol, ethanol and water. The photosensitising composition may further comprise at least one photosensitising compound. The present invention also provides a method of treating and/or preventing conditions caused by microorganisms in a subject.
摘要翻译: 本发明提供一种光敏组合物,其包含以下混合物:至少一种表面活性剂; 至少一种酒精; 和/或水,条件是当至少一种表面活性剂是醇时,它不同于至少一种醇。 特别地,组合物可以包含甘油,乙醇和水的混合物。 或者,组合物可以包含聚乙二醇,乙醇和水的混合物。 光敏组合物还可包含至少一种光敏化合物。 本发明还提供了治疗和/或预防受试者微生物引起的病症的方法。
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公开(公告)号:US20110027384A1
公开(公告)日:2011-02-03
申请号:US12936126
申请日:2009-04-06
申请人: Anil Kishen , Saji George
发明人: Anil Kishen , Saji George
IPC分类号: A61K33/40 , A61K31/025 , A61K31/03 , A61K31/02 , A61K31/662 , A61K33/20 , A61K31/10 , A61P31/00
摘要: The present invention provides a photosensitising composition comprising a mixture of at least one oxygen carrier, at least one oxidising agent and at least one surfactant, and its uses. The ratio of the at least one oxygen carrier to the at least one oxidising agent to the at least one surfactant may be in the range of 50:40:10 to 80:19.8:0.2. The photosensitising composition may be used for treating and/or preventing conditions caused by microorganisms.
摘要翻译: 本发明提供了包含至少一种氧载体,至少一种氧化剂和至少一种表面活性剂的混合物的光敏组合物及其用途。 至少一种氧载体与至少一种氧化剂与至少一种表面活性剂的比例可以在50:40:10至80:19.8:0.2的范围内。 光敏组合物可用于治疗和/或预防微生物引起的病症。
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公开(公告)号:US10568961B2
公开(公告)日:2020-02-25
申请号:US12936126
申请日:2009-04-06
申请人: Anil Kishen , Saji George
发明人: Anil Kishen , Saji George
摘要: The present invention provides a photosensitising composition comprising a mixture of at least one oxygen carrier, at least one oxidising agent and at least one surfactant, and its uses. The ratio of the at least one oxygen carrier to the at least one oxidising agent to the at least one surfactant may be in the range of 50:40:10 to 80:19.8:0.2. The photosensitising composition may be used for treating and/or preventing conditions caused by microorganisms.
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公开(公告)号:US20160065185A1
公开(公告)日:2016-03-03
申请号:US14472809
申请日:2014-08-29
申请人: Anis M. Jarrar , John M. Boyer , Saji George , David R. Tipple
发明人: Anis M. Jarrar , John M. Boyer , Saji George , David R. Tipple
IPC分类号: H03K3/037 , H03K19/20 , G06F11/07 , H03K19/0175
CPC分类号: H03K3/0375 , G06F11/0721 , G06F11/0772 , H03K3/0372 , H03K19/0175 , H03K19/20
摘要: A processing system includes a processor core, a peripheral component, and a flip-flop unit in at least one of the processor core and the peripheral component. The flip-flop unit can include a master latch, and two slave latches coupled to an output of the master latch. The first slave latch is formed over a first doped well region of a semiconductor substrate. The second slave latch is formed over a second doped well region of the semiconductor substrate. A comparator is coupled to an output of the first slave latch and to an output of the second slave latch. An output of the comparator indicates whether a state stored in the first slave latch is the same as a state stored in the second slave latch.
摘要翻译: 处理系统包括在处理器核心和外围部件中的至少一个中的处理器核心,外围部件和触发器单元。 触发器单元可以包括主锁存器和耦合到主锁存器的输出的两个从锁存器。 第一从锁存器形成在半导体衬底的第一掺杂阱区上。 第二从锁存器形成在半导体衬底的第二掺杂阱区上。 比较器耦合到第一从锁存器的输出端和第二从锁存器的输出端。 比较器的输出指示存储在第一从锁存器中的状态是否与存储在第二从锁存器中的状态相同。
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公开(公告)号:US08263579B2
公开(公告)日:2012-09-11
申请号:US13012463
申请日:2011-01-24
申请人: Koteppa Pari , Girish Badrinath Mahajan , Nidhi Tomar , Vijaya Phani Kumar Yemparala , Asha Adrian Kulkarni-Almeida , Saji George
发明人: Koteppa Pari , Girish Badrinath Mahajan , Nidhi Tomar , Vijaya Phani Kumar Yemparala , Asha Adrian Kulkarni-Almeida , Saji George
IPC分类号: C07D498/06 , C07C291/08 , A61K31/655 , A61K31/5365 , A61P29/00
CPC分类号: C07C245/02 , B82Y30/00 , C07D498/04 , C09B67/0005 , C09B67/0013 , C12P13/008 , C12P17/188 , C12R1/01
摘要: This invention relates to novel compounds obtained by fermentation of Myxobacteria strain (PM0670013/MTCC 5570). The present invention further relates to the processes for the production of the novel anti-inflammatory compounds, to the culture no. PM0670013 (MTCC 5570), and to pharmaceutical compositions containing compounds of the present invention as an active ingredient and its use in medicines for the treatment of inflammatory diseases or disorders mediated by proinflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-α) and/or interleukins such as IL-6, having anti-inflammatory activity The invention also includes all stereoisomeric forms of compounds of the present invention.
摘要翻译: 本发明涉及通过发酵霉菌菌株(PM0670013 / MTCC5570)获得的新化合物。 本发明还涉及生产新型抗炎化合物的方法, PM0670013(MTCC5570),以及含有本发明化合物作为活性成分的药物组合物及其在治疗由促炎细胞因子如肿瘤坏死因子-α(TNF-α)和介导的炎性疾病或病症的药物中的用途 /或具有抗炎活性的诸如IL-6的白细胞介素本发明还包括本发明化合物的所有立体异构形式。
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公开(公告)号:US20120190651A1
公开(公告)日:2012-07-26
申请号:US13012463
申请日:2011-01-24
申请人: Koteppa Pari , Girish Badrinath Mahajan , Nidhi Tomar , Vijaya Phani Kumar Yemparala , Asha Adrian Kulkarni-Almeida , Saji George
发明人: Koteppa Pari , Girish Badrinath Mahajan , Nidhi Tomar , Vijaya Phani Kumar Yemparala , Asha Adrian Kulkarni-Almeida , Saji George
IPC分类号: A61K31/655 , A61K31/5365 , C07C245/02 , A61P1/00 , A61P19/00 , A61P17/06 , A61P9/00 , A61P31/14 , A61P29/00 , A61P25/28 , A61P11/00 , A61P35/00 , C12P17/18 , C12P13/00 , C09B39/00 , C07D491/044
CPC分类号: C07C245/02 , B82Y30/00 , C07D498/04 , C09B67/0005 , C09B67/0013 , C12P13/008 , C12P17/188 , C12R1/01
摘要: This invention relates to novel compounds obtained by fermentation of Myxobacteria strain (PM0670013/MTCC 5570). The present invention further relates to the processes for the production of the novel anti-inflammatory compounds, to the culture no. PM0670013 (MTCC 5570), and to pharmaceutical compositions containing compounds of the present invention as an active ingredient and its use in medicines for the treatment of inflammatory diseases or disorders mediated by proinflammatory cytokines such as Tumor Necrosis Factor-alpha (TNF-α) and/or interleukins such as IL-6, having anti-inflammatory activity The invention also includes all stereoisomeric forms of compounds of the present invention.
摘要翻译: 本发明涉及通过发酵霉菌菌株(PM0670013 / MTCC5570)获得的新化合物。 本发明还涉及生产新型抗炎化合物的方法, PM0670013(MTCC5570),以及含有本发明化合物作为活性成分的药物组合物及其在治疗由促炎细胞因子如肿瘤坏死因子-α(TNF-α)和介导的炎性疾病或病症的药物中的用途 /或具有抗炎活性的诸如IL-6的白细胞介素本发明还包括本发明化合物的所有立体异构形式。
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公开(公告)号:US09264021B1
公开(公告)日:2016-02-16
申请号:US14472809
申请日:2014-08-29
申请人: Anis M. Jarrar , John M. Boyer , Saji George , David R. Tipple
发明人: Anis M. Jarrar , John M. Boyer , Saji George , David R. Tipple
IPC分类号: H03K19/003 , H03K3/037 , H03K19/0175 , H03K19/20 , G06F11/07
CPC分类号: H03K3/0375 , G06F11/0721 , G06F11/0772 , H03K3/0372 , H03K19/0175 , H03K19/20
摘要: A processing system includes a processor core, a peripheral component, and a flip-flop unit in at least one of the processor core and the peripheral component. The flip-flop unit can include a master latch, and two slave latches coupled to an output of the master latch. The first slave latch is formed over a first doped well region of a semiconductor substrate. The second slave latch is formed over a second doped well region of the semiconductor substrate. A comparator is coupled to an output of the first slave latch and to an output of the second slave latch. An output of the comparator indicates whether a state stored in the first slave latch is the same as a state stored in the second slave latch.
摘要翻译: 处理系统包括在处理器核心和外围部件中的至少一个中的处理器核心,外围部件和触发器单元。 触发器单元可以包括主锁存器和耦合到主锁存器的输出的两个从锁存器。 第一从锁存器形成在半导体衬底的第一掺杂阱区上。 第二从锁存器形成在半导体衬底的第二掺杂阱区上。 比较器耦合到第一从锁存器的输出端和第二从锁存器的输出端。 比较器的输出指示存储在第一从锁存器中的状态是否与存储在第二从锁存器中的状态相同。
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