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    Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
    4.
    发明授权
    Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent 失效
    溶液聚合法制备降解以释放生理活性剂的聚合物

    公开(公告)号：US07662864B2

    公开(公告)日：2010-02-16

    申请号：US10861881

    申请日：2004-06-04

    申请人： Suseela Kanamathareddy ,  Stephen Goodrich ,  Yun Choe

    发明人： Suseela Kanamathareddy ,  Stephen Goodrich ,  Yun Choe

    IPC分类号： A61K47/32 ,  A61K31/43

    CPC分类号： A61K9/0024 ,  A61K47/34 ,  A61L27/34 ,  A61L27/54 ,  A61L2300/21 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/604

    摘要： Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devices, and the like that benefit from the controlled release of an agent(s) over a period of time. The polymers are prepared by a process involving various alternative and sequential steps that allow the design a priori of products with specific characteristics. The polymers are suitable as delivery systems, either by themselves, as compositions, formulations or devices.

    摘要翻译： 释放活性或可活化剂的酐聚合物具有预先选择的性质，例如分子量，柔韧性，硬度，粘合性和其它有价值的性质。 聚合物适用于在一段时间内受益于试剂的受控释放的组合物，制剂，涂料，装置等中。 聚合物通过涉及各种替代和顺序步骤的方法制备，其允许先验地设计具有特定特征的产品。 聚合物本身适合作为递送系统，作为组合物，制剂或装置。

    Method for selectively inhibiting reuptake of serotonin and norepinephrine using yeast extract
    5.
    发明申请
    Method for selectively inhibiting reuptake of serotonin and norepinephrine using yeast extract 有权
    使用酵母提取物选择性抑制5-羟色胺和去甲肾上腺素再摄取的方法

    公开(公告)号：US20060140974A1

    公开(公告)日：2006-06-29

    申请号：US11141497

    申请日：2005-05-31

    申请人： Yun Choe ,  Il Kang ,  Hyung Suh ,  Young Choi ,  Hee Yun ,  Kyung Kim ,  Sang Ahn ,  Ki Kim ,  Won Hwang ,  Jin Kim

    发明人： Yun Choe ,  Il Kang ,  Hyung Suh ,  Young Choi ,  Hee Yun ,  Kyung Kim ,  Sang Ahn ,  Ki Kim ,  Won Hwang ,  Jin Kim

    IPC分类号： A61K36/064 ,  A61K36/06

    CPC分类号： A61K36/064 ,  A23L33/145 ,  A23P20/20 ,  A23V2002/00 ,  A61K36/06 ,  A23V2250/218 ,  A23V2200/31 ,  A23V2200/322 ,  A23V2200/332

    摘要： A yeast extract or yeast-derived bioactive peptide having an activity of selectively inhibiting reuptake of serotonin and norepinephrine, which can be effectively used in preventing or treating various diseases related to reuptake of serotonin and norepinephrine, especially depression, anxiety, stress, fatigue and obesity are provided. Also, a yeast extract or yeast-derived bioactive peptide having activities as an anti-stress agent, an anti-fatigue agent, premenstrual syndrome (PMS) and menstrual pain relaxants, and a brain-neurotrophic factor, and a method for preparing the bioactive peptide are provided. The yeast extract or yeast-derived bioactive peptide is effective in relieving stress, nervousness, anxiety, tension, insomnia, fatigue, and imbalance in the autonomic nerve regulation. Therefore, the yeast extract or yeast-derived bioactive peptide is vailable as an anti-depression agent, an anti-anxiety agent, an anti-stress agent, an anti-fatigue agent, an anti-obesity agent, premenstrual syndrome and menstrual pain relaxants, a bain-neurotrophin, and a source of active foods having these activities.

    摘要翻译： 具有选择性抑制5-羟色胺和去甲肾上腺素再摄取的活性的酵母提取物或酵母衍生生物活性肽，其可有效用于预防或治疗与再摄取5-羟色胺和去甲肾上腺素，特别是抑郁，焦虑，压力，疲劳和肥胖有关的各种疾病 被提供。 此外，具有活性作为抗应激剂，抗疲劳剂，经前综合征（PMS）和月经痛松弛剂的酵母提取物或酵母衍生的生物活性肽和脑神经营养因子，以及制备生物活性物质的方法 提供肽。 酵母提取物或酵母衍生的生物活性肽有效缓解压力，紧张，焦虑，紧张，失眠，疲劳，自主神经调节失调。 因此，酵母提取物或酵母衍生的生物活性肽作为抗抑郁剂，抗焦虑剂，抗应激剂，抗疲劳剂，抗肥胖剂，经前综合征和月经痛缓解剂 ，一种贝宁神经营养因子，以及具有这些活性的活性食物的来源。