摘要:
Piperidino-3,4-dihydrocarbostyril compounds represented by the formula: ##STR1## wherein R.sup.1 represents a hydroxy group or an acyloxy group having 2 to 11 carbon atoms; one of R.sup.2 and R.sup.3 represents a nitro group, a cyano group, an alkoxycarbonyl group having 2 to 7 carbon atoms, an alkyl group having 1 to 4 carbon atoms, a haloalkyl group having 1 to 3 carbons atoms, or a halogen atom, and the other represents a hydrogen atom; and pharmaceutically acceptable salts thereof, exhibit platelet aggregation inhibiting activity and thus being useful as therapeutic agents for the prevention or treatment of cerebral ischemic disorders and arterial ischemic disorders.
摘要翻译:由下式表示的哌啶子基-3,4-二氢喹诺酮化合物:其中R 1表示羟基或具有2至11个碳原子的酰氧基; R 2和R 3中的一个表示硝基,氰基,具有2至7个碳原子的烷氧基羰基,具有1至4个碳原子的烷基,具有1至3个碳原子的卤代烷基或卤素原子,以及 另一个表示氢原子; 其药学上可接受的盐具有血小板聚集抑制活性,因此可用作预防或治疗脑缺血障碍和动脉缺血障碍的治疗剂。
摘要:
A poly(phenylene ether) resin composed of structural units represented by the general formula: ##STR1## (wherein R.sup.1, R.sup.2 and R.sup.3 represent each alkyl, cycloalkyl, etc. or H (provided that two or more of R.sup.1, R.sup.2 and R.sup.3 do not represent H at the same time), or one of R.sup.1, R.sup.2 and R.sup.3 represents alkyl or H while the others together form a saturated ring, or R.sup.1, R.sup.2 and R.sup.3 together form an aromatic ring; A represents alkyl; p is an integer of from 3 to 5; and Y.sup.- represents a pharmaceutically acceptable acid residue) and/or structural units represented by the general formula: ##STR2## (wherein R.sup.4, R.sup.5 and R.sup.6 represents each alkyl, cycloalkyl, etc. or H (provided that two or more of R.sup.4, R.sup.5 and R.sup.6 do not represent H at the same time), or one of R.sup.4, R.sup.5 and R.sup.6 represents alkyl or H while the others together form a saturated ring, or R.sup.4, R.sup.5 and R.sup.6 together form an aromatic ring; and A, p and Y.sup.- have same meanings as defined above) and structural units represented by the general formula: ##STR3## (wherein R.sup.7 and R.sup.8 represents each alkyl, cycloalkyl, etc. or together form a saturated ring; q is an integer of from 3 to 20; and A, p, and Y.sup.- have same meanings as defined above) wherein the sum of the contents of the structural units represented by the general formula (I) and the structural units represented by the general formula (II) amounts to 40 to 96% by mole and the content of the structural units represented by the general formula (III) amounts to 4 to 60% by mole based upon the content of phenylene ether component and a process for producing the same. The poly(phenylene ether) resins have the effect of adsorbing bile acids and are useful as a cholesterol reducing agent.
摘要:
Provided is a carbon catalyst having an excellent catalytic activity on the decomposition of hydrogen peroxide. The carbon catalyst is a carbon catalyst for decomposing hydrogen peroxide, which is obtained by impregnating a carbonized material, which is obtained by carbonization of raw materials containing an organic compound as a carbon source, a metal, and an electrically conductive carbon material, with a metal, and subjecting the resultant to a heat treatment.
摘要:
Provided is a carbon catalyst having an excellent catalytic activity on the decomposition of hydrogen peroxide. The carbon catalyst is a carbon catalyst for decomposing hydrogen peroxide, which is obtained by impregnating a carbonized material, which is obtained by carbonization of raw materials containing an organic compound as a carbon source, a metal, and an electrically conductive carbon material, with a metal, and subjecting the resultant to a heat treatment.
摘要:
A support member with excellent contact with the member to which the support member is attached, that is, a metal support member which supports a shaft directly or through a bearing and which has a plurality of the projections at its outer circumferential surface, wherein the plurality of the projections are formed at the outer circumferential surface as a whole at the time of casting of the support member and wherein at least part of the projections have thin-waisted shapes or a plastic support member which supports a shaft directly or through a bearing and which has a plurality of the projections at its outer circumferential surface, wherein the plurality of the projections are formed at the outer circumferential surface as a whole at the time of molding of the support member and wherein at least part of the projections have thin-waisted shapes.
摘要:
A support member with excellent contact with the member to which the support member is attached, that is, a metal support member which supports a shaft directly or through a bearing and which has a plurality of the projections at its outer circumferential surface, wherein the plurality of the projections are formed at the outer circumferential surface as a whole at the time of casting of the support member and wherein at least part of the projections have thin-waisted shapes or a plastic support member which supports a shaft directly or through a bearing and which has a plurality of the projections at its outer circumferential surface, wherein the plurality of the projections are formed at the outer circumferential surface as a whole at the time of molding of the support member and wherein at least part of the projections have thin-waisted shapes.
摘要:
Crystals of a salt of 4′-{2-[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethylamino]ethoxy}-3-isopropyl-3′,5′-dimethylbiphenyl-4-carboxylic acid. The α type, β type and γ type crystals produced by treating hydrochloride of 4′-{2-[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethylamino]ethoxy}-3-isopropyl-3′,5′-dimethylbiphenyl-4-carboxylic acid with specified solvents, which can be discriminated by the characteristic diffraction peaks of powder X-ray diffractometry and the like.