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    Tissue attachment devices and methods for prosthetic heart valves
    1.
    发明授权
    Tissue attachment devices and methods for prosthetic heart valves 有权
    用于假体心脏瓣膜的组织附接装置和方法

    公开(公告)号：US08696743B2

    公开(公告)日：2014-04-15

    申请号：US12424768

    申请日：2009-04-16

    申请人： Arin N. Holecek ,  Carolyn Majkrzak ,  Carol E. Eberhardt ,  Billie J. Millwee ,  Thao M. Nguyen ,  Janice L. Shay ,  Cynthia H. Chiu ,  Tara S. Kupumbati

    发明人： Arin N. Holecek ,  Carolyn Majkrzak ,  Carol E. Eberhardt ,  Billie J. Millwee ,  Thao M. Nguyen ,  Janice L. Shay ,  Cynthia H. Chiu ,  Tara S. Kupumbati

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2412 ,  A61F2220/0075

    摘要： A multi-leaflet valve, which includes at least two leaflets, an outer tube, and a seam protector for each seam. Each seam protector is positioned to be in contact with a portion of the outer tube, with tube portions and leaflet ends being positioned between adjacent seam protection pieces. The seam protectors provide a lower stress surface about which the leaflets can bend or flex during their opening and closing. The seam protectors may include an enlarged end portion with an extending straight surface, an inverted U-shaped structure, or a sinusoidal-shaped structure, for example. The valve can further be provided with a seam cover or protector that is stitched onto the seam allowance of the layers of one or more of the seams. The seams can be provided with one or more inserts to fill spaces between adjacent tissue layers and create tension in certain material sheets.

    摘要翻译： 一种多叶瓣阀，其包括至少两个传单，外管和用于每个接缝的接缝保护器。 每个缝隙保护器定位成与外管的一部分接触，其中管部分和小叶末端位于相邻的接缝保护件之间。 接缝保护器提供较低的应力表面，小叶在打开和关闭过程中可绕其弯曲或弯曲。 接缝保护器可以包括具有延伸的直表面，倒U形结构或正弦形结构的扩大端部。 该阀还可以设置有接缝盖或保​​护器，其缝合在一个或多个接缝的层的接缝余量上。 接缝可以设置有一个或多个插入物以填充相邻组织层之间的空间并且在某些材料片材中产生张力。

    TISSUE ATTACHMENT DEVICES AND METHODS FOR PROSTHETIC HEART VALVES
    2.
    发明申请
    TISSUE ATTACHMENT DEVICES AND METHODS FOR PROSTHETIC HEART VALVES 有权
    组织连接装置和预防心脏瓣膜的方法

    公开(公告)号：US20100023120A1

    公开(公告)日：2010-01-28

    申请号：US12424768

    申请日：2009-04-16

    申请人： Arin N. Holecek ,  Carolyn Majkrzak ,  Carol E. Eberhardt ,  Billie J. Millwee ,  Thao M. Nguyen ,  Janice L. Shay ,  Cynthia H. Chiu ,  Tara S. Kupumbati

    发明人： Arin N. Holecek ,  Carolyn Majkrzak ,  Carol E. Eberhardt ,  Billie J. Millwee ,  Thao M. Nguyen ,  Janice L. Shay ,  Cynthia H. Chiu ,  Tara S. Kupumbati

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2412 ,  A61F2220/0075

    摘要： A multi-leaflet valve, which includes at least two leaflets, an outer tube, and a seam protector for each seam. Each seam protector is positioned to be in contact with a portion of the outer tube, with tube portions and leaflet ends being positioned between adjacent seam protection pieces. The seam protectors provide a lower stress surface about which the leaflets can bend or flex during their opening and closing. The seam protectors may include an enlarged end portion with an extending straight surface, an inverted U-shaped structure, or a sinusoidal-shaped structure, for example. The valve can further be provided with a seam cover or protector that is stitched onto the seam allowance of the layers of one or more of the seams. The seams can be provided with one or more inserts to fill spaces between adjacent tissue layers and create tension in certain material sheets.

    摘要翻译： 一种多叶瓣阀，其包括至少两个传单，外管和用于每个接缝的接缝保护器。 每个缝隙保护器定位成与外管的一部分接触，其中管部分和小叶末端位于相邻的接缝保护件之间。 接缝保护器提供较低的应力表面，小叶在打开和关闭过程中可绕其弯曲或弯曲。 接缝保护器可以包括具有延伸的直表面，倒U形结构或正弦形结构的扩大端部。 该阀还可以设置有接缝盖或保​​护器，其缝合在一个或多个接缝的层的接缝余量上。 接缝可以设置有一个或多个插入物以填充相邻组织层之间的空间并且在某些材料片材中产生张力。

    Prosthetic heart valve, prosthetic heart valve assembly and method for making same
    3.
    发明授权
    Prosthetic heart valve, prosthetic heart valve assembly and method for making same 有权
    假心脏瓣膜，假体心脏瓣膜组装及其制作方法

    公开(公告)号：US08136218B2

    公开(公告)日：2012-03-20

    申请号：US12424682

    申请日：2009-04-16

    申请人： Billie J. Millwee ,  Janice L. Shay ,  Carolyn Majkrzak ,  Melissa Young ,  Tara S. Kupumbati

    发明人： Billie J. Millwee ,  Janice L. Shay ,  Carolyn Majkrzak ,  Melissa Young ,  Tara S. Kupumbati

    IPC分类号： B23P17/00 ,  A01J21/00

    CPC分类号： A61F2/2415 ,  A61F2220/0075

    摘要： A mold assembly for forming a prosthetic valve having at least one leaflet, which includes a first plate having a first side from which at least one leaflet mold extends and a planar portion adjacent the at least one leaflet mold, wherein the planar portion has multiple access holes through its thickness, and a second plate having at least one mold opening and a planar portion adjacent the at least one mold opening, wherein each mold opening is sized and shaped to correspond with one of the leaflet molds of the first plate, and wherein the planar portion has multiple access holes through its thickness. The second plate is positionable relative to the first plate so that each of the leaflet molds of the first plate extend at least partially through one of the mold openings of the second plate.

    摘要翻译： 一种用于形成具有至少一个叶片的假体瓣膜的模具组件，其包括具有第一侧的第一板，至少一个叶片模具从该第一侧延伸，以及与所述至少一个叶片模具相邻的平面部分，其中所述平面部分具有多个通路 穿过其厚度的孔，以及具有至少一个模具开口和邻近所述至少一个模具开口的平面部分的第二板，其中每个模具开口的尺寸和形状设置成与所述第一板的所述叶片模具之一相对应，并且其中 平面部分具有穿过其厚度的多个入口孔。 第二板可相对于第一板定位，使得第一板的每个叶片模具至少部分地延伸穿过第二板的一个模具开口。

    Prosthetic heart valve, prosthetic heart valve assembly and method for making same
    4.
    发明授权
    Prosthetic heart valve, prosthetic heart valve assembly and method for making same 有权
    假心脏瓣膜，假体心脏瓣膜组装及其制作方法

    公开(公告)号：US08677601B2

    公开(公告)日：2014-03-25

    申请号：US13370725

    申请日：2012-02-10

    申请人： Billie J. Millwee ,  Janice L. Shay ,  Carolyn Majkrzak ,  Melissa Young ,  Tara S. Kupumbati

    发明人： Billie J. Millwee ,  Janice L. Shay ,  Carolyn Majkrzak ,  Melissa Young ,  Tara S. Kupumbati

    IPC分类号： B23P17/00

    CPC分类号： A61F2/2415 ,  A61F2220/0075

    摘要： A method of forming a leaflet of a prosthetic valve includes placing a first piece of material on a working surface. A leaflet mold is placed on the first piece of material, and provides a outer peripheral shape comprising a curved portion. A second piece of material is placed over the first piece and the leaflet mold. The first and second pieces of material are stitched to one another along at least a portion of the curved portion of the leaflet mold. The leaflet mold is removed from first and second pieces of material.

    摘要翻译： 形成人造瓣膜的小叶的方法包括将第一片材料放置在工作表面上。 将小叶模具放置在第一块材料上，并提供包括弯曲部分的外周形状。 将第二片材料放置在第一片和小叶模上。 第一和第二片材料沿着小叶模具的弯曲部分的至少一部分彼此缝合。 从第一和第二块材料中移除小叶模具。

    PROSTHETIC HEART VALVE, PROSTHETIC HEART VALVE ASSEMBLY AND METHOD FOR MAKING SAME
    5.
    发明申请
    PROSTHETIC HEART VALVE, PROSTHETIC HEART VALVE ASSEMBLY AND METHOD FOR MAKING SAME 有权
    前置心脏瓣膜，前置心脏瓣膜组件及其制造方法

    公开(公告)号：US20120137521A1

    公开(公告)日：2012-06-07

    申请号：US13370725

    申请日：2012-02-10

    申请人： Billie J. Millwee ,  Janice L. Shay ,  Carolyn Majkrzak ,  Melissa Young ,  Tara S. Kupumbati

    发明人： Billie J. Millwee ,  Janice L. Shay ,  Carolyn Majkrzak ,  Melissa Young ,  Tara S. Kupumbati

    IPC分类号： B21D51/16

    CPC分类号： A61F2/2415 ,  A61F2220/0075

    摘要： A method of forming a leaflet of a prosthetic valve includes placing a first piece of material on a working surface. A leaflet mold is placed on the first piece of material, and provides a outer peripheral shape comprising a curved portion. A second piece of material is placed over the first piece and the leaflet mold. The first and second pieces of material are stitched to one another along at least a portion of the curved portion of the leaflet mold. The leaflet mold is removed from first and second pieces of material.

    摘要翻译： 形成人造瓣膜的小叶的方法包括将第一片材料放置在工作表面上。 将小叶模具放置在第一块材料上，并提供包括弯曲部分的外周形状。 将第二片材料放置在第一片和小叶模上。 第一和第二片材料沿着小叶模具的弯曲部分的至少一部分彼此缝合。 从第一和第二块材料中移除小叶模具。

    PROSTHETIC HEART VALVE, PROSTHETIC HEART VALVE ASSEMBLY AND METHOD FOR MAKING SAME
    6.
    发明申请
    PROSTHETIC HEART VALVE, PROSTHETIC HEART VALVE ASSEMBLY AND METHOD FOR MAKING SAME 有权
    前置心脏瓣膜，前置心脏瓣膜组件及其制造方法

    公开(公告)号：US20100011564A1

    公开(公告)日：2010-01-21

    申请号：US12424682

    申请日：2009-04-16

    申请人： Billie J. Millwee ,  Janice L. Shay ,  Carolyn Majkrzak ,  Melissa Young ,  Tara S. Kupumbati

    发明人： Billie J. Millwee ,  Janice L. Shay ,  Carolyn Majkrzak ,  Melissa Young ,  Tara S. Kupumbati

    IPC分类号： B23P17/00 ,  B29C39/00

    CPC分类号： A61F2/2415 ,  A61F2220/0075

    摘要： A mold assembly for forming a prosthetic valve having at least one leaflet, which includes a first plate having a first side from which at least one leaflet mold extends and a planar portion adjacent the at least one leaflet mold, wherein the planar portion has multiple access holes through its thickness, and a second plate having at least one mold opening and a planar portion adjacent the at least one mold opening, wherein each mold opening is sized and shaped to correspond with one of the leaflet molds of the first plate, and wherein the planar portion has multiple access holes through its thickness. The second plate is positionable relative to the first plate so that each of the leaflet molds of the first plate extend at least partially through one of the mold openings of the second plate.

    摘要翻译： 一种用于形成具有至少一个叶片的假体瓣膜的模具组件，其包括具有第一侧的第一板，至少一个叶片模具从该第一侧延伸，以及与所述至少一个叶片模具相邻的平面部分，其中所述平面部分具有多个通路 穿过其厚度的孔，以及具有至少一个模具开口和邻近所述至少一个模具开口的平面部分的第二板，其中每个模具开口的尺寸和形状设置成与所述第一板的所述叶片模具之一相对应，并且其中 平面部分具有穿过其厚度的多个入口孔。 第二板可相对于第一板定位，使得第一板的每个叶片模具至少部分地延伸穿过第二板的一个模具开口。