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    Tissue attachment devices and methods for prosthetic heart valves
    1.
    发明授权
    Tissue attachment devices and methods for prosthetic heart valves 有权
    用于假体心脏瓣膜的组织附接装置和方法

    公开(公告)号：US08696743B2

    公开(公告)日：2014-04-15

    申请号：US12424768

    申请日：2009-04-16

    申请人： Arin N. Holecek ,  Carolyn Majkrzak ,  Carol E. Eberhardt ,  Billie J. Millwee ,  Thao M. Nguyen ,  Janice L. Shay ,  Cynthia H. Chiu ,  Tara S. Kupumbati

    发明人： Arin N. Holecek ,  Carolyn Majkrzak ,  Carol E. Eberhardt ,  Billie J. Millwee ,  Thao M. Nguyen ,  Janice L. Shay ,  Cynthia H. Chiu ,  Tara S. Kupumbati

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2412 ,  A61F2220/0075

    摘要： A multi-leaflet valve, which includes at least two leaflets, an outer tube, and a seam protector for each seam. Each seam protector is positioned to be in contact with a portion of the outer tube, with tube portions and leaflet ends being positioned between adjacent seam protection pieces. The seam protectors provide a lower stress surface about which the leaflets can bend or flex during their opening and closing. The seam protectors may include an enlarged end portion with an extending straight surface, an inverted U-shaped structure, or a sinusoidal-shaped structure, for example. The valve can further be provided with a seam cover or protector that is stitched onto the seam allowance of the layers of one or more of the seams. The seams can be provided with one or more inserts to fill spaces between adjacent tissue layers and create tension in certain material sheets.

    摘要翻译： 一种多叶瓣阀，其包括至少两个传单，外管和用于每个接缝的接缝保护器。 每个缝隙保护器定位成与外管的一部分接触，其中管部分和小叶末端位于相邻的接缝保护件之间。 接缝保护器提供较低的应力表面，小叶在打开和关闭过程中可绕其弯曲或弯曲。 接缝保护器可以包括具有延伸的直表面，倒U形结构或正弦形结构的扩大端部。 该阀还可以设置有接缝盖或保​​护器，其缝合在一个或多个接缝的层的接缝余量上。 接缝可以设置有一个或多个插入物以填充相邻组织层之间的空间并且在某些材料片材中产生张力。

    TISSUE ATTACHMENT DEVICES AND METHODS FOR PROSTHETIC HEART VALVES
    2.
    发明申请
    TISSUE ATTACHMENT DEVICES AND METHODS FOR PROSTHETIC HEART VALVES 有权
    组织连接装置和预防心脏瓣膜的方法

    公开(公告)号：US20100023120A1

    公开(公告)日：2010-01-28

    申请号：US12424768

    申请日：2009-04-16

    申请人： Arin N. Holecek ,  Carolyn Majkrzak ,  Carol E. Eberhardt ,  Billie J. Millwee ,  Thao M. Nguyen ,  Janice L. Shay ,  Cynthia H. Chiu ,  Tara S. Kupumbati

    发明人： Arin N. Holecek ,  Carolyn Majkrzak ,  Carol E. Eberhardt ,  Billie J. Millwee ,  Thao M. Nguyen ,  Janice L. Shay ,  Cynthia H. Chiu ,  Tara S. Kupumbati

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2412 ,  A61F2220/0075

    摘要： A multi-leaflet valve, which includes at least two leaflets, an outer tube, and a seam protector for each seam. Each seam protector is positioned to be in contact with a portion of the outer tube, with tube portions and leaflet ends being positioned between adjacent seam protection pieces. The seam protectors provide a lower stress surface about which the leaflets can bend or flex during their opening and closing. The seam protectors may include an enlarged end portion with an extending straight surface, an inverted U-shaped structure, or a sinusoidal-shaped structure, for example. The valve can further be provided with a seam cover or protector that is stitched onto the seam allowance of the layers of one or more of the seams. The seams can be provided with one or more inserts to fill spaces between adjacent tissue layers and create tension in certain material sheets.

    摘要翻译： 一种多叶瓣阀，其包括至少两个传单，外管和用于每个接缝的接缝保护器。 每个缝隙保护器定位成与外管的一部分接触，其中管部分和小叶末端位于相邻的接缝保护件之间。 接缝保护器提供较低的应力表面，小叶在打开和关闭过程中可绕其弯曲或弯曲。 接缝保护器可以包括具有延伸的直表面，倒U形结构或正弦形结构的扩大端部。 该阀还可以设置有接缝盖或保​​护器，其缝合在一个或多个接缝的层的接缝余量上。 接缝可以设置有一个或多个插入物以填充相邻组织层之间的空间并且在某些材料片材中产生张力。

    METHODS AND APPARATUSES FOR ASSEMBLY OF A PERICARDIAL PROSTHETIC HEART VALVE
    3.
    发明申请
    METHODS AND APPARATUSES FOR ASSEMBLY OF A PERICARDIAL PROSTHETIC HEART VALVE 有权
    方法和装置用于组合心脏前置心脏瓣膜

    公开(公告)号：US20100018447A1

    公开(公告)日：2010-01-28

    申请号：US12424742

    申请日：2009-04-16

    申请人： Arin N. Holecek ,  Carolyn Majkrzak ,  Janice L. Shay ,  Carol E. Eberhardt ,  David L. Kulcinski

    发明人： Arin N. Holecek ,  Carolyn Majkrzak ,  Janice L. Shay ,  Carol E. Eberhardt ,  David L. Kulcinski

    IPC分类号： D05B75/00 ,  D05B23/00 ,  B23P19/04

    CPC分类号： A61F2/2415 ,  A61F2220/0075 ,  Y10T29/53552

    摘要： A method of assembling a prosthetic valve using sheets of material, such as pericardium material, polymer or bioengineered film, or other material. The method provides an accurate and repeatable system of making pericardial valves in which sheets or pieces of material are held securely in place relative to each other throughout the steps of assembling the valve. In addition, methods of the present invention include maintaining consistent alignment of the fixtures and pericardium material throughout the valve assembly process and utilize features that make the tooling components easy to assemble and handle. Certain aspects of the invention can be used to help establish a repeatable sewing and cutting technique for creating a pattern shape for valve leaflets, establishing stitch lengths, and determining the exact placement of stitches.

    摘要翻译： 使用诸如心包材料，聚合物或生物工程薄膜或其他材料的材料片组装人造瓣膜的方法。 该方法提供精确和可重复的制造心包瓣膜的系统，其中片材或片材在组装阀门的整个步骤中相对于彼此牢固地保持在适当的位置。 此外，本发明的方法包括在整个阀门组装过程中保持固定装置和心包膜材料的一致的对准，并利用使加工组件易于组装和处理的特征。 本发明的某些方面可以用于建立可重复的缝合和切割技术，以创建用于瓣叶的图案形状，建立针迹长度以及确定针迹的确切位置。

    Methods and apparatuses for assembly of a pericardial prosthetic heart valve
    4.
    发明授权
    Methods and apparatuses for assembly of a pericardial prosthetic heart valve 有权
    用于组装心包假体心脏瓣膜的方法和装置

    公开(公告)号：US08312825B2

    公开(公告)日：2012-11-20

    申请号：US12424742

    申请日：2009-04-16

    申请人： Arin N. Holecek ,  Carolyn Majkrzak ,  Janice L. Shay ,  Carol E. Eberhardt ,  David L. Kulcinski

    发明人： Arin N. Holecek ,  Carolyn Majkrzak ,  Janice L. Shay ,  Carol E. Eberhardt ,  David L. Kulcinski

    IPC分类号： D05B39/00 ,  A61F2/24

    CPC分类号： A61F2/2415 ,  A61F2220/0075 ,  Y10T29/53552

    摘要： A method of assembling a prosthetic valve using sheets of material, such as pericardium material, polymer or bioengineered film, or other material. The method provides an accurate and repeatable system of making pericardial valves in which sheets or pieces of material are held securely in place relative to each other throughout the steps of assembling the valve. In addition, methods of the present invention include maintaining consistent alignment of the fixtures and pericardium material throughout the valve assembly process and utilize features that make the tooling components easy to assemble and handle. Certain aspects of the invention can be used to help establish a repeatable sewing and cutting technique for creating a pattern shape for valve leaflets, establishing stitch lengths, and determining the exact placement of stitches.

    摘要翻译： 使用诸如心包材料，聚合物或生物工程薄膜或其他材料的材料片组装人造瓣膜的方法。 该方法提供精确和可重复的制造心包瓣膜的系统，其中片材或片材在组装阀门的整个步骤中相对于彼此牢固地保持在适当的位置。 此外，本发明的方法包括在整个阀门组装过程中保持固定装置和心包膜材料的一致的对准，并利用使加工组件易于组装和处理的特征。 本发明的某些方面可以用于建立可重复的缝合和切割技术，以创建用于瓣叶的图案形状，建立针迹长度以及确定针迹的确切位置。

    Stents for prosthetic heart valves
    9.
    发明授权
    Stents for prosthetic heart valves 有权
    假体心脏瓣膜支架

    公开(公告)号：US08628566B2

    公开(公告)日：2014-01-14

    申请号：US12358980

    申请日：2009-01-23

    申请人： Carol E. Eberhardt ,  Charles Tabor ,  Carolyn Majkrzak ,  Timothy R. Ryan ,  Melissa Denton ,  Maria Botrous ,  Janice L. Shay

    发明人： Carol E. Eberhardt ,  Charles Tabor ,  Carolyn Majkrzak ,  Timothy R. Ryan ,  Melissa Denton ,  Maria Botrous ,  Janice L. Shay

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2418 ,  A61F2220/0075

    摘要： A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the tubular body portion.

    摘要翻译： 一种支架式阀，包括支架结构，该支架结构包括大体上管状的主体部分，该主体部分具有第一端部，第二端部，内部区域，纵向轴线以及大致平行于纵向轴线围绕主体部分的周边延伸的多个垂直线 ，其中所述多个垂直导线包括多个连合线和位于相邻合金线之间的至少一个结构线，以及多个V形线结构，其具有第一端，第二端和在所述第一和第二端之间的峰 其中，每个V形结构的第一端从第一垂直线延伸，并且每个V形结构的第二端从与所述第一垂直导线相邻的第二垂直导线延伸，其中每个V形结构被定向 使得其峰值相对于主体部分的第一和第二端面向相同的方向，以及阀结构，其包括附接到ste的多个传单 nt结构在管状体部分内。

    Stents for Prosthetic Heart Valves
    10.
    发明申请
    Stents for Prosthetic Heart Valves 有权
    假体心脏瓣膜支架

    公开(公告)号：US20090292350A1

    公开(公告)日：2009-11-26

    申请号：US12358980

    申请日：2009-01-23

    申请人： Carol E. Eberhardt ,  Charles Tabor ,  Carolyn Majkrzak ,  Timothy R. Ryan ,  Melissa Denton ,  Maria Botrous ,  Janice L. Shay

    发明人： Carol E. Eberhardt ,  Charles Tabor ,  Carolyn Majkrzak ,  Timothy R. Ryan ,  Melissa Denton ,  Maria Botrous ,  Janice L. Shay

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2418 ,  A61F2220/0075

    摘要： A stented valve including a stent structure including a generally tubular body portion having a first end, a second end, an interior area, a longitudinal axis, and a plurality of vertical wires extending generally parallel to the longitudinal axis around a periphery of the body portion, wherein the plurality of vertical wires includes multiple commissure wires and at least one structural wire positioned between adjacent commissure wires, and a plurality of V-shaped wire structures having a first end, a second end, and a peak between the first and second ends, wherein a first end of each V-shaped structure extends from a first vertical wire and a second end of each V-shaped structure extends from a second vertical wire that is adjacent to the first vertical wire, wherein each V-shaped structure is oriented so that its peak is facing in the same direction relative to the first and second ends of the body portion, and a valve structure including a plurality of leaflets attached to the stent structure within the tubular body portion.

    摘要翻译： 一种支架式阀，包括支架结构，该支架结构包括大体上管状的主体部分，该主体部分具有第一端部，第二端部，内部区域，纵向轴线以及大致平行于纵向轴线围绕主体部分的周边延伸的多个垂直线 ，其中所述多个垂直导线包括多个连合线和位于相邻合金线之间的至少一个结构线，以及多个V形线结构，其具有第一端，第二端和在所述第一和第二端之间的峰 其中，每个V形结构的第一端从第一垂直线延伸，并且每个V形结构的第二端从与所述第一垂直线相邻的第二垂直线延伸，其中每个V形结构被定向 使得其峰值相对于主体部分的第一和第二端面向相同的方向，以及阀结构，其包括附接到ste的多个传单 nt结构在管状体部分内。