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1.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 213P1F11 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和相关蛋白质213P1F11用于治疗和检测癌症公开(公告)号：US20090181891A1
公开(公告)日：2009-07-16
申请号：US12357253
申请日：2009-01-21
申请人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
CPC分类号： C07K14/82 , A01K2217/05 , A01K2267/0331
摘要： A novel gene (designated 213P1F11) and its encoded protein, and variants thereof, are described wherein 213P1F11 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 213P1F11 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 213P1F11 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 213P1F11 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为213P1F11）及其编码的蛋白及其变体，其中213P1F11在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，213P1F11提供诊断，预后， 癌症的预防和/或治疗靶标。 213P1F11基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与213P1F11反应的抗体或T细胞可用于主动或被动免疫。
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2.发明申请NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 202P5A5 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和对照蛋白质202P5A5有用于治疗和检测癌症公开(公告)号：US20110201052A1
公开(公告)日：2011-08-18
申请号：US13021202
申请日：2011-02-04
CPC分类号： C12N5/0693 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K47/6851 , A61K2039/505 , C07K14/435 , C07K14/47 , C07K2319/00 , G01N33/57484 , Y02A50/466
摘要： A novel gene 202P5A5 and its encoded protein, and variants thereof, are described wherein 202P5A5 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 202P5A5 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 202P5A5 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 202P5A5 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因202P5A5及其编码的蛋白质及其变体，其中202P5A5在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，202P5A5提供诊断，预后，预防和/ 或癌症的治疗靶标。 202P5A5基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与202P5A5反应的抗体或T细胞可用于主动或被动免疫。
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3.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 184P1E2 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和相关蛋白质184P1E2有用的治疗和检测癌症公开(公告)号：US20110110952A1
公开(公告)日：2011-05-12
申请号：US12985245
申请日：2011-01-05
申请人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
CPC分类号： C07K14/47 , A61K38/00 , C12N9/78 , Y10T436/25
摘要： A novel gene (designated 184P1E2) and its encoded protein, and variants thereof, are described wherein 184P1E2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 184P1E2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 184P1E2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 184P1E2 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为184P1E2）及其编码的蛋白及其变体，其中184P1E2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，184P1E2提供诊断，预后， 癌症的预防和/或治疗靶标。 184P1E2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与184P1E2反应的抗体或T细胞可用于主动或被动免疫。
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4.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 184P1E2 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和相关蛋白质184P1E2有用的治疗和检测癌症公开(公告)号：US20090148854A1
公开(公告)日：2009-06-11
申请号：US12357154
申请日：2009-01-21
申请人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
IPC分类号： C12Q1/68 , G01N33/566 , G01N33/53 , C12Q1/02
CPC分类号： C07K14/47 , A61K38/00 , C12N9/78 , Y10T436/25
摘要： A novel gene (designated 184P1E2) and its encoded protein, and variants thereof, are described wherein 184P1E2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 184P1E2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 184P1E2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 184P1E2 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为184P1E2）及其编码的蛋白及其变体，其中184P1E2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，184P1E2提供诊断，预后， 癌症的预防和/或治疗靶标。 184P1E2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与184P1E2反应的抗体或T细胞可用于主动或被动免疫。
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5.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 121P1F1 USEFUL IN TREATMENT AND DETECTION OF CANCER 审中-公开核酸和相关蛋白121P1F1可用于治疗和检测癌症公开(公告)号：US20120076789A1
公开(公告)日：2012-03-29
申请号：US13243297
申请日：2011-09-23
申请人： Pia M. CHALLITA-EID , Rene S. Hubert , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Wangmao Ge , Aya Jakobovits
发明人： Pia M. CHALLITA-EID , Rene S. Hubert , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Wangmao Ge , Aya Jakobovits
CPC分类号： C07K16/30 , A61K39/00 , A61K2039/505 , C07K14/47
摘要： A novel gene (designated 121P1F1) and its encoded protein, and variants thereof, are described wherein 121P1F1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 121P1F1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 121P1F1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 121P1F1 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为121P1F1）及其编码的蛋白质及其变体，其中121P1F1在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，121P1F1提供诊断，预后， 癌症的预防和/或治疗靶标。 121P1F1基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与121P1F1反应的抗体或T细胞可用于主动或被动免疫。
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6.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 161P5C5 USEFUL IN TREATMENT AND DETECTION OF CANCER 失效核酸和相关蛋白161P5C5被用于治疗和检测癌症公开(公告)号：US20100144637A1
公开(公告)日：2010-06-10
申请号：US12646863
申请日：2009-12-23
申请人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Robert Kendall Morrison , Wangmao Ge , Aya Jakobovits
IPC分类号： A61K31/7088 , C07H21/04 , C12N15/63 , C12N5/10 , C12P21/02 , C07K14/435 , A61K38/17 , A61P35/00
CPC分类号： C07K14/4748 , A61K39/00 , Y02A50/466 , Y10T436/143333
摘要： A novel gene (designated 161P5C5) and its encoded protein, and variants thereof, are described wherein 161P5C5 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P5C5 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P5C5 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P5C5 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为161P5C5）及其编码的蛋白及其变体，其中161P5C5在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，161P5C5提供诊断，预后， 癌症的预防和/或治疗靶标。 161P5C5基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与161P5C5反应的抗体或T细胞可用于主动或被动免疫。
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公开(公告)号：US20110086437A1
公开(公告)日：2011-04-14
申请号：US12914894
申请日：2010-10-28
申请人： Arthur B. RAITANO , Pia M. CHALLITA-EID , Wangmao GE , Juan J. PEREZ-VILLAR , Steven B. KANNER , Aya JAKOBOVITS
发明人： Arthur B. RAITANO , Pia M. CHALLITA-EID , Wangmao GE , Juan J. PEREZ-VILLAR , Steven B. KANNER , Aya JAKOBOVITS
IPC分类号： G01N33/53
CPC分类号： C07K14/47 , A61K47/646 , A61K47/6851 , A61K47/6901 , A61K51/1045
摘要： A novel gene 109P1D4 and its encoded protein, and variants thereof, are described wherein 109P1D4 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 109P1D4 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 109P1D4 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 109P1D4 can be used in active or passive immunization.
摘要翻译： 描述了一种新颖的基因109P1D4及其编码的蛋白及其变体，其中109P1D4在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，109P1D4提供诊断，预后，预防和/ 或癌症的治疗靶标。 109P1D4基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与109P1D4反应的抗体或T细胞可用于主动或被动免疫。
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公开(公告)号：US20100099111A1
公开(公告)日：2010-04-22
申请号：US12643927
申请日：2009-12-21
申请人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Aya Jakobovits
发明人： Pia M. CHALLITA-EID , Arthur B. Raitano , Mary Faris , Rene S. Hubert , Karen Jane Meyrick Morrison , Aya Jakobovits
CPC分类号： C07K16/30 , A61K31/7088 , A61K39/00 , A61K51/1045 , A61K2039/505 , C07K14/47 , C07K16/18 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3061 , C07K16/3069 , C07K16/40 , C07K2317/20 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2319/30 , C12N9/16 , C12Q1/6886 , C12Q2600/158 , G01N33/57492 , Y02A50/466
摘要： Antibodies and methods of using same against products of the gene designated 161P2F10B and its encoded protein are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit a humoral or cellular immune response.
摘要翻译： 其中161P2F10B在正常成人组织中表现出组织特异性表达，其中161P2F10B及其编码蛋白的基因的产物使用的抗体和方法被描述，其在表I所列的癌症中异常表达。因此，161P2F10B提供诊断，预后 ，癌症的预防和/或治疗靶标。 161P2F10B基因或其片段或其编码的蛋白质或其片段可用于引发体液或细胞免疫应答。
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