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公开(公告)号：US20110034677A1
公开(公告)日：2011-02-10
申请号：US12650164
申请日：2009-12-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US08580509B2
公开(公告)日：2013-11-12
申请号：US13483176
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
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公开(公告)号：US20070212702A1
公开(公告)日：2007-09-13
申请号：US11519397
申请日：2006-09-12
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Xiao-Wei Sun , Sven Perner , Lee Charles , Mark Rubin
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Xiao-Wei Sun , Sven Perner , Lee Charles , Mark Rubin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US20130040858A1
公开(公告)日：2013-02-14
申请号：US13483157
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US09284609B2
公开(公告)日：2016-03-15
申请号：US13483157
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
IPC分类号： C12P19/34 , C07H21/04 , C12Q1/68 , C12N15/113 , G01N33/574
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
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公开(公告)号：US08211645B2
公开(公告)日：2012-07-03
申请号：US12650164
申请日：2009-12-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US20080207714A1
公开(公告)日：2008-08-28
申请号：US11936871
申请日：2007-11-08
申请人： Arul Chinnaiyan , Scott Tomlins , Daniel Rhodes , Rohit Mehra
发明人： Arul Chinnaiyan , Scott Tomlins , Daniel Rhodes , Rohit Mehra
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/136 , G01N33/57415 , G01N2333/726 , G01N2800/50
摘要： The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to AGTR1 and LBP markers for breast cancer.
摘要翻译： 本发明涉及用于癌症诊断，研究和治疗的组合物和方法，包括但不限于癌症标志物。 特别地，本发明涉及用于乳腺癌的AGTR1和LBP标记物。
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公开(公告)号：US08969527B2
公开(公告)日：2015-03-03
申请号：US13483142
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
IPC分类号： C07K16/00 , C12Q1/68 , C12N15/113 , G01N33/574
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US20120296070A1
公开(公告)日：2012-11-22
申请号：US13483142
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
IPC分类号： C07K16/18
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
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公开(公告)号：US20120295809A1
公开(公告)日：2012-11-22
申请号：US13483176
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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