利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

35 条记录 (耗时 0.029 秒)

    Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity
    1.
    发明授权
    Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity 有权

    公开(公告)号：US10421710B2

    公开(公告)日：2019-09-24

    申请号：US14559520

    申请日：2014-12-03

    申请人： Auspex Pharmaceuticals, Inc.

    发明人： Thomas G. Gant ,  Sepehr Sarshar ,  Soon Hyung Woo

    IPC分类号： C07C211/64 ,  C07B59/00 ,  C07C215/64 ,  C07C217/74 ,  C07D265/16

    摘要： Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management of psychotropic disorders, anxiety disorder, generalized anxiety disorder, depression, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, hot flashes, senile dementia, migraine, hepatopulmonary syndrome, chronic pain, nociceptive pain, neuropathic pain, painful diabetic retinopathy, bipolar depression, obstructive sleep apnea, psychiatric disorders, premenstrual dysphoric disorder, social phobia, social anxiety disorder, urinary incontinence, anorexia, bulimia nervosa, obesity, ischemia, head injury, calcium overload in brain cells, drug dependence, attention deficit hyperactivity disorder, fibromyalgia, irritable bowel syndrome, and/or premature ejaculation are described.

    SUBSTITUTED N-ARYL PYRIDINONES
    5.
    发明申请
    SUBSTITUTED N-ARYL PYRIDINONES 审中-公开
    取代的N-亚苄基吡啶

    公开(公告)号：US20150250777A1

    公开(公告)日：2015-09-10

    申请号：US14718993

    申请日：2015-05-21

    申请人： Auspex Pharmaceuticals, Inc.

    发明人： Thomas G. Gant ,  Sepehr Sarshar

    IPC分类号： A61K31/4418

    CPC分类号： A61K31/4418 ,  A61K45/06 ,  C07B59/002 ,  C07D213/64

    摘要： Disclosed herein are substituted N-Aryl pyridinone fibrotic inhibitors and/or collagen infiltration modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.

    摘要翻译： 本文公开了取代的N-芳基吡啶酮纤维化抑制剂和/或式I的胶原浸润调节剂，其制备方法，其药物组合物及其使用方法。

    Substituted Phenethylamines with Serotoninergic and/or Norepinephrinergic Activity
    7.
    发明申请
    Substituted Phenethylamines with Serotoninergic and/or Norepinephrinergic Activity 审中-公开

    公开(公告)号：US20200172469A1

    公开(公告)日：2020-06-04

    申请号：US16566197

    申请日：2019-09-10

    申请人： Auspex Pharmaceuticals, Inc.

    发明人： Thomas G. Gant ,  Sepehr Sarshar ,  Soon Hyung Woo

    IPC分类号： C07C211/64 ,  C07B59/00 ,  C07C215/64 ,  C07C217/74 ,  C07D265/16

    摘要： Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management of psychotropic disorders, anxiety disorder, generalized anxiety disorder, depression, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, hot flashes, senile dementia, migraine, hepatopulmonary syndrome, chronic pain, nociceptive pain, neuropathic pain, painful diabetic retinopathy, bipolar depression, obstructive sleep apnea, psychiatric disorders, premenstrual dysphoric disorder, social phobia, social anxiety disorder, urinary incontinence, anorexia, bulimia nervosa, obesity, ischemia, head injury, calcium overload in brain cells, drug dependence, attention deficit hyperactivity disorder, fibromyalgia, irritable bowel syndrome, and/or premature ejaculation are described.