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公开(公告)号：US11457816B2
公开(公告)日：2022-10-04
申请号：US16447937
申请日：2019-06-20
申请人： Avava, Inc.
摘要： A system includes a focus optic configured to converge an electromagnetic radiation (EMR) beam to a focal region located along an optical axis. The system also includes a detector configured to detect a signal radiation emanating from a predetermined location along the optical axis. The system additionally includes a controller configured to adjust a parameter of the EMR beam based in part on the signal radiation detected by the detector. The system also includes a window located a predetermined depth away from the focal region, between the focal region and the focus optic along the optical axis, wherein the window is configured to make contact with a surface of a tissue.
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公开(公告)号：US20190314085A1
公开(公告)日：2019-10-17
申请号：US16381736
申请日：2019-04-11
申请人： Avava, Inc.
摘要： A method includes generating a plurality of primary beams from a laser beam, and generating, from a primary beam one or more secondary beams. The method also includes focusing the first secondary beam to a first focal region in the target tissue and the second secondary beam to a second focal region in the target tissue. The first focal region and the second focal region can be located at different depths in the target tissue.
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公开(公告)号：US11344358B2
公开(公告)日：2022-05-31
申请号：US16444496
申请日：2019-06-18
申请人： Avava, Inc.
摘要： A method includes depositing within a predetermined region of a target tissue with a plurality of dopant particles. The method also includes focusing a laser beam to a focal region that overlaps with at least a portion of the predetermined region. The focal region includes at least a first dopant particle of the plurality of dopant particles. The method further includes adjusting a first parameter of the laser beam to generate plasma within a plasma volume comprising the first dopant particle.
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公开(公告)号：US20210212568A1
公开(公告)日：2021-07-15
申请号：US17214168
申请日：2021-03-26
申请人： Avava, Inc.
摘要： A system includes a focus optic configured to converge an electromagnetic radiation (EMR) beam to a focal region located along an optical axis. The system also includes a detector configured to detect a signal radiation emanating from a predetermined location along the optical axis. The system additionally includes a controller configured to adjust a parameter of the EMR beam based in part on the signal radiation detected by the detector. The system also includes a window located a predetermined depth away from the focal region, between the focal region and the focus optic along the optical axis, wherein the window is configured to make contact with a surface of a tissue.
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公开(公告)号：US20210045809A1
公开(公告)日：2021-02-18
申请号：US17089290
申请日：2020-11-04
申请人： Avava, Inc.
IPC分类号： A61B18/20
摘要： A cooling element includes a frame including one or more datums. The cooling element also includes a first window including a first proximal surface and a first distal surface. The first window is sealed to the frame. The cooling element further includes a second window sealed to the frame. The second window includes a second proximal surface and a second distal surface. The second window is configured to contact a target tissue or a tissue adjacent to the target tissue via the second distal surface. The cooing element also includes a coolant chamber located between the first distal surface of the first window and the second proximal surface of the second window and configured to receive a coolant. The first window, the second window and the coolant chamber are configured to receive and electromagnetic radiation (EMR), and transmit a portion of the received EMR to the target tissue.
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公开(公告)号：US20200205896A1
公开(公告)日：2020-07-02
申请号：US16814340
申请日：2020-03-10
申请人： Avava, Inc.
IPC分类号： A61B18/20
摘要： A cooling element includes a frame including one or more datums. The cooling element also includes a first window including a first proximal surface and a first distal surface. The first window is sealed to the frame. The cooling element further includes a second window sealed to the frame. The second window includes a second proximal surface and a second distal surface. The second window is configured to contact a target tissue or a tissue adjacent to the target tissue via the second distal surface. The cooing element also includes a coolant chamber located between the first distal surface of the first window and the second proximal surface of the second window and configured to receive a coolant. The first window, the second window and the coolant chamber are configured to receive and electromagnetic radiation (EMR), and transmit a portion of the received EMR to the target tissue.
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公开(公告)号：US20190388149A1
公开(公告)日：2019-12-26
申请号：US16447176
申请日：2019-06-20
申请人： Avava, Inc.
摘要： An optical system includes an array of optical elements configured to receive a primary laser beam and generate a plurality of sub-beams. The array of optical elements includes a plurality of optical elements that are configured to simultaneously focus the plurality of sub-beams to a plurality of focal regions in a target tissue. A pitch of the array of optical elements ranges from about 1 mm to about 3 mm. A numerical aperture of one or more optical elements of the plurality of optical element ranges from about 0.3 to about 1. A first sub-beam of the plurality sub-beams is configured to generate plasma in a first focal region of the plurality of focal regions.
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公开(公告)号：US20190187461A1
公开(公告)日：2019-06-20
申请号：US16219801
申请日：2018-12-13
申请人： Avava, Inc.
CPC分类号： G02B26/128 , G06K7/10613 , H01S3/11
摘要： An electromagnetic beam scanning system and corresponding method of use is provided. The system includes a motor, a reciprocating mechanism, and a focus optic. The motor is configured to generate a rotational movement. The reciprocating mechanism is operatively coupled with the motor and configured to convert the rotational movement to a reciprocating movement including a plurality of strokes along a first scanned axis. The reciprocating movement has a constant speed over a portion of at least one stroke of the plurality of strokes. The focus optic is operatively coupled to the reciprocating mechanism such that the focus optic moves experiences the reciprocating movement of the reciprocating mechanism. The focus optic is configured to focus an electromagnetic radiation (EMR) beam incident upon the focus optic to a focus along an optical axis substantially orthogonal to the first scanned axis.
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公开(公告)号：US20240131354A1
公开(公告)日：2024-04-25
申请号：US18400365
申请日：2023-12-29
申请人： Avava, Inc.
CPC分类号： A61N5/0616 , A61M35/003 , A61N2005/007
摘要： According to some embodiments, a system for fractionally treating tissue includes: an electromagnetic radiation (EMR) source configured to generate an EMR beam having a transverse ring energy profile; an optic configured to converge the EMR beam to a focal region located within a tissue; and, a window assembly located down-beam from the optic configured to cool the tissue when placed in contact with an outer surface of the tissue.
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公开(公告)号：US11691216B2
公开(公告)日：2023-07-04
申请号：US16445194
申请日：2019-06-18
申请人： Avava, Inc.
IPC分类号： B23K26/064 , B23K26/03 , B23K26/062 , B23K103/00
CPC分类号： B23K26/064 , B23K26/032 , B23K26/062 , B23K2103/50
摘要： A method includes depositing a plurality of dopant particles within a predetermined region of a transparent material. The method also includes focusing a laser beam along an optical axis to a focal region that overlaps with at least a portion of the predetermined region. The focal region can irradiate at least a first dopant particle of the plurality of dopant particles. The method further includes adjusting a parameter of the laser beam to generate a plasma configured to form an inclusion within the transparent material. The method additionally includes scanning the focal region along a path within the transparent material to elongate the inclusion generally along the path.
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