公开(公告)号：US06571650B2

公开(公告)日：2003-06-03

申请号：US10029668

申请日：2001-10-22

申请人： Avinash Dalmia ,  Otto J. Prohaska ,  Paul G. Saviano ,  Gitesh Kumar

发明人： Avinash Dalmia ,  Otto J. Prohaska ,  Paul G. Saviano ,  Gitesh Kumar

IPC分类号： G01N112

CPC分类号： G01N1/2226 ,  G01N2001/2229 ,  G01N2001/2241

摘要： The invention relates to an apparatus and method for providing a modifiable headspace for measuring a concentration of volatile releases from a sample. The invention includes a collapsible housing for containing the air sample and a plurality of spacers between the housing and the sample surface for separating them from one another. The plurality of spacers permit the distance between the housing and the sample to be adjustable.

摘要翻译： 本发明涉及一种提供用于测量来自样品的挥发性释放浓度的可修改顶部空间的装置和方法。 本发明包括用于容纳空气样本的可折叠壳体和在壳体和样品表面之间的多个间隔件，用于将它们彼此分离。 多个间隔件允许壳体和样品之间的距离是可调节的。

公开(公告)号：US06430513B1

公开(公告)日：2002-08-06

申请号：US09479642

申请日：2000-01-07

申请人： Yongdong Wang ,  David H. Tracy ,  Paul G. Saviano ,  Alan M. Ganz ,  Koichi Nishikida ,  Gitesh Kumar

发明人： Yongdong Wang ,  David H. Tracy ,  Paul G. Saviano ,  Alan M. Ganz ,  Koichi Nishikida ,  Gitesh Kumar

IPC分类号： G01N3100

CPC分类号： A61B5/6814 ,  A61B5/14546 ,  A61B5/14553 ,  G01N21/49

摘要： Constituents such as oxy- and deoxy-hemoglobin are monitored non-invasively in an animal organ such as a brain with a spectrometric instrument by passing radiation through the organ. Concentrations are computed from the spectral intensities and from a statistical correlation model. To predetermine the correlation model, the procedures are effected for a plurality of organs of a same type with each organ having established concentrations of the selected constituents, and the correlation model is statistically determined from the concentrations and corresponding intensities. For more accuracy computations are normalized to path length which may be determined by utilizing several discrete wavelengths with RF modulations.

摘要翻译： 通过使辐射通过器官，通过光谱仪器在诸如脑的动物器官中非侵入性地监测诸如氧和血红蛋白的成分。 浓度从光谱强度和统计相关模型计算。 为了预先确定相关模型，对于具有确定的所选组分浓度的每个器官，对于多个相同类型的器官进行该程序，并且根据浓度和相应的强度统计地确定相关模型。 为了更准确的计算，归一化到可以通过利用具有RF调制的几个离散波长来确定的路径长度。

公开(公告)号：US06195574B1

公开(公告)日：2001-02-27

申请号：US09385242

申请日：1999-08-28

申请人： Gitesh Kumar ,  Joseph L. DiCesare

发明人： Gitesh Kumar ,  Joseph L. DiCesare

IPC分类号： A61B500

CPC分类号： A61B5/6814 ,  A61B5/14553

摘要： Constituents such as oxy- and deoxy-hemoglobin are monitored non-invasively in an animal organ such as a brain with a spectrometric instrument by passing radiation through the organ. An input beam has a plurality of discrete wavelengths modulated with radio frequency. Output radiation is received by a detector from which output amplitude and output phase are determined for each wavelength. Absorption coefficient is computed from the amplitude and phase, and concentrations of constituents are thereby calculated.

摘要翻译： 通过使辐射通过器官，通过光谱仪器在诸如脑的动物器官中非侵入性地监测诸如氧和血红蛋白的成分。 输入光束具有用射频调制的多个离散波长。 输出辐射由检测器接收，从每个波长确定输出幅度和输出相位。 从振幅和相位计算吸收系数，由此计算组分的浓度。