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公开(公告)号：US10188410B2
公开(公告)日：2019-01-29
申请号：US11971172
申请日：2008-01-08
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
摘要： In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T≤1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.
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公开(公告)号：US20110004105A1
公开(公告)日：2011-01-06
申请号：US12830145
申请日：2010-07-02
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
IPC分类号： A61B8/00
CPC分类号： A61M37/0092 , A61B17/22004 , A61B17/2202 , A61B2017/00084 , A61B2017/00088 , A61B2017/00092 , A61B2017/22008 , A61B2017/22084 , A61B2018/0041 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61N7/022 , A61N2007/0039 , A61N2007/0078
摘要： An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The ultrasound catheter system comprises a catheter having at least one ultrasonic element and a control system configured to generate power parameters that drive the at least one ultrasonic element to generate ultrasonic energy. The control system is configured to vary at least one of the power parameters and at least one physiological parameter by ramping the power parameter and the physiological parameter between two set of minimum and maximum values.
摘要翻译： 公开了一种超声波导管系统和用于在患者的脉管系统或组织内的治疗部位操作超声波导管的方法。 超声导管系统包括具有至少一个超声波元件和被配置为产生驱动该至少一个超声波元件以产生超声波能量的功率参数的控制系统的导管。 控制系统被配置为通过在两组最小值和最大值之间斜升功率参数和生理参数来改变功率参数和至少一个生理参数中的至少一个。
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公开(公告)号：US09849273B2
公开(公告)日：2017-12-26
申请号：US13454983
申请日：2012-04-24
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
CPC分类号： A61M37/0092 , A61B17/22004 , A61B17/2202 , A61B2017/00084 , A61B2017/00088 , A61B2017/00092 , A61B2017/22008 , A61B2017/22084 , A61B2018/0041 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61N7/022 , A61N2007/0039 , A61N2007/0078
摘要： An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The ultrasound catheter system comprises a catheter having at least one ultrasonic element and a control system configured to generate power parameters that drive the at least one ultrasonic element to generate ultrasonic energy. The control system is configured to vary at least one of the power parameters and at least one physiological parameter by repeatedly cycling the power parameter and the physiological parameter through two set of values.
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公开(公告)号：US20120271203A1
公开(公告)日：2012-10-25
申请号：US13454983
申请日：2012-04-24
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
CPC分类号： A61M37/0092 , A61B17/22004 , A61B17/2202 , A61B2017/00084 , A61B2017/00088 , A61B2017/00092 , A61B2017/22008 , A61B2017/22084 , A61B2018/0041 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61N7/022 , A61N2007/0039 , A61N2007/0078
摘要： An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The ultrasound catheter system comprises a catheter having at least one ultrasonic element and a control system configured to generate power parameters that drive the at least one ultrasonic element to generate ultrasonic energy. The control system is configured to vary at least one of the power parameters and at least one physiological parameter by repeatedly cycling the power parameter and the physiological parameter through two set of values.
摘要翻译： 公开了一种超声波导管系统和用于在患者的脉管系统或组织内的治疗部位操作超声波导管的方法。 超声导管系统包括具有至少一个超声波元件和被配置为产生驱动该至少一个超声波元件以产生超声波能量的功率参数的控制系统的导管。 控制系统被配置为通过两组值重复循环功率参数和生理参数来改变功率参数和至少一个生理参数中的至少一个。
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公开(公告)号：US20090018472A1
公开(公告)日：2009-01-15
申请号：US12170342
申请日：2008-07-09
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
IPC分类号： A61N7/00
CPC分类号： A61B17/2202 , A61B2017/00181 , A61B2017/00185 , A61B2017/0019 , A61B2017/00194
摘要： In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T≦1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.
摘要翻译： 在本发明的一个实施例中，将超声能量施加到患者脉管系统内的治疗部位的方法包括将超声波辐射构件定位在患者脉管系统内的治疗部位。 该方法还包括激活超声波辐射构件以在循环周期T 1 = 1秒产生超声能量的脉冲。 诸如峰值功率，脉冲宽度，脉冲重复频率和频率的声学参数或它们的任何组合可以非线性地改变。
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公开(公告)号：US20080171965A1
公开(公告)日：2008-07-17
申请号：US11971172
申请日：2008-01-08
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
CPC分类号： A61B17/2202 , A61B2017/00181 , A61B2017/00185 , A61B2017/0019 , A61B2017/00194
摘要： In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T≦1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.
摘要翻译： 在本发明的一个实施例中，将超声能量施加到患者脉管系统内的治疗部位的方法包括将超声波辐射构件定位在患者脉管系统内的治疗部位。 该方法还包括激活超声波辐射构件以在循环周期T 1 = 1秒产生超声能量的脉冲。 诸如峰值功率，脉冲宽度，脉冲重复频率和频率的声学参数或它们的任何组合可以非线性地改变。
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公开(公告)号：US10182833B2
公开(公告)日：2019-01-22
申请号：US12170342
申请日：2008-07-09
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
摘要： In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T≤1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.
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公开(公告)号：US08192391B2
公开(公告)日：2012-06-05
申请号：US12830145
申请日：2010-07-02
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
CPC分类号： A61M37/0092 , A61B17/22004 , A61B17/2202 , A61B2017/00084 , A61B2017/00088 , A61B2017/00092 , A61B2017/22008 , A61B2017/22084 , A61B2018/0041 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61N7/022 , A61N2007/0039 , A61N2007/0078
摘要： An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The method of operating an ultrasonic catheter comprises advancing a catheter with at least one ultrasonic element to a treatment site in a patient's vascular system or tissue, driving the at least one ultrasonic element to generate ultrasonic energy, delivering a therapeutic compound to the treatment site through the catheter, and varying a power parameter and a physiological parameter of the ultrasonic element by ramping the power parameter and the physiological parameter between two set of minimum and maximum values.
摘要翻译： 公开了一种超声波导管系统和用于在患者的脉管系统或组织内的治疗部位操作超声波导管的方法。 操作超声波导管的方法包括将具有至少一个超声波元件的导管推进到患者血管系统或组织中的治疗部位，驱动所述至少一个超声波元件以产生超声能量，将治疗化合物递送至治疗部位，通过 导管，并且通过在两组最小值和最大值之间递增功率参数和生理参数来改变超声波元件的功率参数和生理参数。
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9.发明申请公开(公告)号：US20100081934A1
公开(公告)日：2010-04-01
申请号：US12629775
申请日：2009-12-02
申请人： Azita Soltani , Douglas R. Hansmann
发明人： Azita Soltani , Douglas R. Hansmann
CPC分类号： A61N7/00 , A61B17/2202 , A61B2017/22001 , A61M37/0092 , A61N2007/0039 , A61N2007/0043
摘要： In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.
摘要翻译： 在本发明的一个实施方案中，治疗位于患者脉管系统内的治疗部位的血管闭塞的方法包括将超声导管定位在治疗部位。 该方法还包括在第一处理阶段期间将微泡治疗化合物从超声导管输送到血管闭塞。 该方法还包括在微泡治疗化合物的递送保持暂停期间，暂停微泡治疗化合物的递送并将超声能量从超声导管输送到第二治疗阶段期间的血管闭塞。
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10.发明申请公开(公告)号：US20050192556A1
公开(公告)日：2005-09-01
申请号：US11046208
申请日：2005-01-28
申请人： Azita Soltani , Douglas Hansmann
发明人： Azita Soltani , Douglas Hansmann
CPC分类号： A61N7/00 , A61B17/2202 , A61B2017/22001 , A61M37/0092 , A61N2007/0039 , A61N2007/0043
摘要： In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble compound and delivering ultrasonic energy from the ultrasound catheter in combination with other therapeutic compounds to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.
摘要翻译： 在本发明的一个实施方案中，治疗位于患者脉管系统内的治疗部位的血管闭塞的方法包括将超声导管定位在治疗部位。 该方法还包括在第一处理阶段期间将微泡治疗化合物从超声导管输送到血管闭塞。 该方法还包括在微泡治疗化合物的递送保持暂停期间，暂停微泡化合物的递送并将超声能量从其他治疗化合物与超声导管输送到第二治疗阶段期间的血管闭塞。
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