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1.发明授权Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-2 and uses thereof 失效编码肿瘤排斥抗原前体MAGE-2的分离的核酸分子及其用途公开(公告)号：US06552180B1
公开(公告)日：2003-04-22
申请号：US09579197
申请日：2000-05-26
IPC分类号： C07H2104
CPC分类号： C07K16/30 , A61K38/00 , A61K39/00 , C07K14/4748
摘要： Isolated nucleic acid molecules are described, which have complements that hybridize to a nucleic acid molecule referred to as MAGE-2. The isolated nucleic acid molecules are expressed in some melanoma cells, as well as other types of cancer cells. The invention also relates to nucleic acid molecules which encode fragments of the proteins encoded by these nucleic acid molecules, and nucleic acid molecules which encode the ultimate product, the so-called tumor rejection antigens.
摘要翻译： 描述了分离的核酸分子，其具有与被称为MAGE-2的核酸分子杂交的互补序列。 分离的核酸分子在一些黑素瘤细胞以及其它类型的癌细胞中表达。 本发明还涉及编码由这些核酸分子编码的蛋白质的片段的核酸分子和编码最终产物的核酸分子，所谓的肿瘤排斥抗原。
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2.发明授权Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-8 and uses thereof 失效编码肿瘤排斥抗原前体MAGE-8的分离的核酸分子及其用途公开(公告)号：US06498021B1
公开(公告)日：2002-12-24
申请号：US09583850
申请日：2000-05-31
申请人： Béatrice Guagler
发明人： Béatrice Guagler
IPC分类号： C12P2106
CPC分类号： C07K16/30 , A61K38/00 , A61K39/00 , C07K14/4748
摘要： The invention relates to nucleic acid molecules which code for the tumor rejection antigen precursor MAGE-8. Also disclosed are vectors, cell lines, and so forth, which utilize the nucleic acid molecule, and optionally, molecules coding for human leukocyte antigen HLA-A1. Use of these materials in therapeutic and diagnostic contexts are also a part of the invention.
摘要翻译： 本发明涉及编码肿瘤排斥抗原前体MAGE-8的核酸分子。 还公开了利用核酸分子和任选的编码人白细胞抗原HLA-A1的分子的载体，细胞系等。 在治疗和诊断环境中使用这些材料也是本发明的一部分。
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3.发明授权Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-6 and uses thereof 失效编码肿瘤排斥抗原前体MAGE-6的分离的核酸分子及其用途公开(公告)号：US06946289B1
公开(公告)日：2005-09-20
申请号：US09583848
申请日：2000-05-31
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , C07K16/30
摘要： The invention relates to nucleic acid molecules which code for the tumor rejection antigen precursor MAGE-6. Also disclosed are vectors, cell lines, and so forth, which utilize the nucleic acid molecule, and optionally, molecules coding for human leukocyte antigen HLA-A1. Use of these materials in therapeutic and diagnostic contexts are also a part of the invention.
摘要翻译： 本发明涉及编码肿瘤排斥抗原前体MAGE-6的核酸分子。 还公开了利用核酸分子和任选的编码人白细胞抗原HLA-A1的分子的载体，细胞系等。 在治疗和诊断环境中使用这些材料也是本发明的一部分。
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公开(公告)号：US07495074B2
公开(公告)日：2009-02-24
申请号：US11253240
申请日：2005-10-17
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , C07K16/30
摘要： The invention relates to nucleic acid molecules which code for the tumor rejection antigen precursor MAGE-3. Also disclosed are vectors, cell lines, and so forth, which utilize the nucleic acid molecule, and optionally, molecules coding for human leukocyte antigen HLA-A1. Uses of these materials in therapeutic and diagnostic contexts are also a part of the invention.
摘要翻译： 本发明涉及编码肿瘤排斥抗原前体MAGE-3的核酸分子。 还公开了利用核酸分子和任选的编码人白细胞抗原HLA-A1的分子的载体，细胞系等。 这些材料在治疗和诊断环境中的使用也是本发明的一部分。
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5.发明授权Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-4 and 41 and uses thereof 失效编码肿瘤排斥抗原前体MAGE-4和41的分离的核酸分子及其用途公开(公告)号：US07199231B1
公开(公告)日：2007-04-03
申请号：US09579543
申请日：2000-05-26
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , C07K16/30
摘要： The invention relates to nucleic acid molecules which code for the tumor rejection antigen precursor MAGE-4 and 41. Also disclosed are vectors, cell lines, and so forth, which utilize the nucleic acid molecule, and optionally, molecules coding for human leukocyte antigen HLA-A1. Use of these materials in therapeutic and diagnostic contexts are also a part of the invention.
摘要翻译： 本发明涉及编码肿瘤排斥抗原前体MAGE-4和41的核酸分子。还公开了利用核酸分子和任选地编码人白细胞抗原HLA的分子的载体，细胞系等 -A1 在治疗和诊断环境中使用这些材料也是本发明的一部分。
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公开(公告)号：US06599699B1
公开(公告)日：2003-07-29
申请号：US09312464
申请日：1999-05-17
IPC分类号： C12Q168
CPC分类号： C07K16/30 , A61K38/00 , A61K39/00 , C07K14/4748
摘要： The invention relates to nucleic acid molecules which code for the tumor rejection antigen precursor MAGE-3. Also disclosed are vectors, cell lines, and so forth, which utilize the nucleic acid molecule, and optionally, molecules coding for human leukocyte antigen HLA-A1. Uses of these materials in therapeutic and diagnostic contexts are also a part of the invention.
摘要翻译： 本发明涉及编码肿瘤排斥抗原前体MAGE-3的核酸分子。 还公开了利用核酸分子和任选的编码人白细胞抗原HLA-A1的分子的载体，细胞系等。 这些材料在治疗和诊断环境中的使用也是本发明的一部分。
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