公开(公告)号：US20230160893A1

公开(公告)日：2023-05-25

申请号：US17916993

申请日：2021-04-06

Applicant: B.R.A.H.M.S GMBH

Inventor： Stefan Ebmeyer ,  Manne Krop ,  Jutta Odarjuk

IPC: G01N33/569 ,  G01N33/74

CPC classification number: G01N33/56983 ,  G01N33/74 ,  G01N2333/165 ,  G01N2800/52 ,  G01N2800/56 ,  G01N2800/12

Abstract: The invention relates to a method for prognosing disease progression in a patient that has or is at risk of developing a severe acute respiratory syndrome (SARS), wherein the method comprises determining a level of pro-adrenomedullin (proADM) or fragment(s) thereof in a sample from the patient, wherein said level indicates the severity of SARS progression. The method is in some embodiments configured for use when a patient exhibits symptoms of a severe acute respiratory syndrome (SARS), a patient exhibits symptoms of infection with a SARS-virus, the patient is infected with a SARS-virus, such as a SARS-coronavirus, such as SARS-CoV2.

公开(公告)号：US20210405070A1

公开(公告)日：2021-12-30

申请号：US16972509

申请日：2019-06-06

Applicant: B.R.A.H.M.S GMBH

Inventor： Darius Wilson ,  Aline Pehla ,  Stefan Ebmeyer ,  Frauke Dreyer

IPC: G01N33/74

Abstract: The invention relates to a method for the diagnosis, prognosis, prediction, risk assessment and/or risk stratification of a subsequent trauma-related complication in a polytrauma patient, comprising providing a sample of said patient, wherein the sample is isolated from the patient after the polytrauma, determining a level of pro ADM or fragment(s) thereof in said sample, wherein said level of pro ADM or fragment(s) thereof correlates with the likelihood of a subsequent trauma-related complication