公开(公告)号：US20020173819A1

公开(公告)日：2002-11-21

申请号：US09862174

申请日：2001-05-21

申请人： BACCHUS VASCULAR, INC.

发明人： Stephen Leeflang ,  Denlse DeMarais ,  Michael Evans

IPC分类号： A61M029/00

CPC分类号： A61B17/22 ,  A61B17/32037 ,  A61B2017/22084 ,  A61B2217/005 ,  A61B2217/007 ,  A61F2/013 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0076 ,  A61F2230/008 ,  A61F2230/0093 ,  A61F2250/0003

摘要： An apparatus includes a jet housing including an inlet and an outlet, and a nozzle within the jet housing for injecting fluid towards the outlet. A filter element is disposed on the inlet, the filter element including openings for preventing particulate larger than a predetermined size from entering the inlet. The jet housing is positioned within a blood vessel, and fluid is injected from the nozzle towards the outlet to create a vacuum at the inlet, thereby causing fluid downstream of the outlet to flow retrograde through the vessel around the jet housing into the inlet. The filter element prevents particulate from entering the inlet, thereby effectively capturing the particulate, which may be aspirated. Alternatively, a filter element is used to filter particulate during a procedure. The filter element everts from a tubular to an everted configuration for capturing particulate.

摘要翻译： 一种装置包括一个包括一个入口和一个出口的喷气式外壳，以及一个用于将流体喷射到出口的射流壳体内的喷嘴。 过滤元件设置在入口上，过滤元件包括用于防止大于预定尺寸的颗粒进入入口的开口。 射流壳体位于血管内，并且流体从喷嘴朝向出口注入以在入口处产生真空，从而使出口下游的流体逆流地流过穿过射流壳体的容器进入入口。 过滤元件防止颗粒进入入口，从而有效地捕获可被吸入的颗粒。 或者，过滤元件用于过滤颗粒物。 过滤器元件从管状件脱离到用于捕获颗粒物的脱开构造。

公开(公告)号：US20030139751A1

公开(公告)日：2003-07-24

申请号：US10278735

申请日：2002-10-21

申请人： BACCHUS VASCULAR INC.

发明人： Michael A. Evans ,  Denise Demarais ,  Dino De Cicco ,  Kelvin Ning ,  Alexander Khairkhahan ,  Tyler Jon Strang ,  Jody Maria Cimbalo ,  Stephen Leeflang

IPC分类号： A61B017/22

CPC分类号： A61B17/320758 ,  A61B17/22 ,  A61B17/22004 ,  A61B2017/00685 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2017/22084 ,  A61B2017/320716 ,  A61B2017/320766 ,  A61M25/0021 ,  A61M25/007 ,  A61M25/0075 ,  A61M25/0105 ,  A61M39/22 ,  A61M2025/1052

摘要： Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, agitate the clot and agent, and aspirate broken-up clot from the blood vessel. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.

摘要翻译： 使用具有注入溶栓剂，搅动凝块和药剂的能力的导管，以及从血管中抽出破碎的凝块来实现凝块破裂和溶解。 导管中的流阻器提供输注和/或抽吸主要集中在血管中的凝块治疗区域，同时还提供可选的输液和/或远离治疗区域的抽吸。 在一些实施例中，输注，抽吸和导丝通过共同内腔。 血栓溶解剂如tPA，链激酶或尿激酶在搅拌器与凝块接合的位置处直接释放到凝块中。 以这种方式，药剂的溶栓活性增强，并且凝块的溶解得到改善。