公开(公告)号：US09828594B2

公开(公告)日：2017-11-28

申请号：US15064269

申请日：2016-03-08

Applicant: BASF ENZYMES LLC

Inventor： Kelvin Wong ,  Jay M. Short ,  Mark J. Burk ,  Grace Desantis ,  Robert Farwell ,  Kelly Chatman

IPC: C12N9/78 ,  C12N15/00 ,  C12P21/06 ,  C12P21/04 ,  C07H21/04 ,  C12P7/42 ,  C12P13/04 ,  C12P41/00 ,  C12P13/00

CPC classification number: C12N9/78 ,  C12N15/00 ,  C12P7/42 ,  C12P13/002 ,  C12P13/04 ,  C12P41/006 ,  C12Y305/05001 ,  Y02P20/52

Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.

公开(公告)号：US09315792B2

公开(公告)日：2016-04-19

申请号：US14297989

申请日：2014-06-06

Applicant: BASF ENZYMES LLC

Inventor： Kelvin Wong ,  Jay M. Short ,  Mark J. Burk ,  Grace DeSantis ,  Robert Farwell ,  Kelly Chatman

IPC: C12N9/78 ,  C12N15/00 ,  C12P21/06 ,  C12P21/04 ,  C07H21/04 ,  C12P7/42 ,  C12P13/04 ,  C12P41/00

CPC classification number: C12N9/78 ,  C12N15/00 ,  C12P7/42 ,  C12P13/002 ,  C12P13/04 ,  C12P41/006 ,  C12Y305/05001 ,  Y02P20/52

Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.